Department of Epidemiology

MS


December 22, 2023

Reliability of IgG serum antibodies, the electronic health record, and self-report in estimating urogenital and extragenital Chlamydia trachomatis infections in men who have sex with men

Few studies have examined the systemic antibody response in extragenital Chlamydia trachomatis (CT) infections. We estimate seroprevalence of IgG serum antibodies to CT among a cohort of men who have sex with men (MSM) with and without current infections stratified by anatomic site. We also examine the reliability of IgG serum antibodies, the electronic health…


Cofactors of neonatal mortality and hospitalization in western Kenya

Although global neonatal mortality has been declining over the past several decades, it remains a major contributor to infant and childhood mortality rates. Determining the biological, psychosocial, and behavioral cofactors of neonatal mortality and hospitalization can help identify high-risk populations and behaviors associated with adverse neonatal health outcomes and will be relevant to research and…


Factors associated with costly and potentially burdensome hospital care among patients with dementia and respiratory failure

Understanding contributors to costly and potentially burdensome hospital care for critically ill patients with dementia is of interest to healthcare systems and may facilitate efforts to ensure care is concordant with patients’ goals. We conducted an electronic health record (EHR)-based retrospective cohort study of 298 adults with dementia identified using International Classification of Diseases codes….


Patterns of acute kidney injury and functional outcome scores in pediatric patients hospitalized with acute respiratory failure

Acute kidney injury (AKI) is diagnosed in up to 30% of children admitted to pediatric intensive care units (PICU) and is strongly associated with morbidity and mortality. In recent years, there has been an increased focus on patient-centered outcomes and quality of life among survivors of AKI. One study of pediatric sepsis patients with AKI…


December 21, 2023

Historical redlining and survival among children, adolescents, and young adults with cancer diagnosed between 2007-2019 in Seattle/Tacoma

Historic redlining has been associated with inferior survival in adult-onset cancers, however whether there is an association in pediatric, adolescent, and young-adult-onset cancers is unknown. Methods: Cancer cases among individuals living in Seattle and Tacoma between 2007-2019 were identified via Cancer Surveillance System. Case redlining status was determined using Home Owner Loans Corporation (HOLC) data…


Outcomes of Kidney Transplantation Among Undocumented Immigrants in the United States

Kidney transplantation is the optimal treatment for end-stage kidney disease (ESKD), but undocumented immigrants in the United States are often excluded from health insurance coverage necessary to undergo kidney transplantation. Arguments in favor of such policies are based on concern that undocumented immigrants face increased risk for graft loss, but transplant outcomes in this population…


Association Between Isolation Source, Clonal Composition, and Antibiotic Resistance Genes in Escherichia coli Samples Collected in Washington State

The growing prevalence of antimicrobial resistance (AMR) represents a significant global health problem. AMR is caused by the overuse of antibiotics in humans, animals, and the environment, making it necessary to apply a One Health approach to address the problem. Methods: We used whole genome sequencing (WGS) data from 1,449 Escherichia coli (E. coli) isolates…


Did California’s 2020 Medi-Cal Expansion Improve Health Insurance Coverage and Mental Health Outcomes Among Young Adults Without US Citizenship? A Population-based, Quasi-Experimental Study

In 2020, California became one of the first states to expand Medicaid (Medi-Cal) to low-income young adults, irrespective of US citizenship. The primary aim of this study was to assess whether California’s 2020 Young Adult Medi-Cal expansion improved healthcare access and mental health outcomes among low-income (<200% Federal Poverty Line) young adults aged 18-25 who…


Prioritizing Out-of-Care Case Investigations in King County, Washington

Health departments need to investigate cases of people with HIV who appear to be out of care but often have insufficient resources to investigate all cases and need a way to prioritize investigations. Methods: In this retrospective cohort analysis, we used classification and regression tree (CART) methodology to develop and validate a decision algorithm for…


Can Artificial Intelligence based Automated CT Brain Interpretation Software help Early Clinical Decision Making for Stroke Patients in Real World Resource Limited Settings with Non-Specialist Physicians? An Interrupted Time Series Study from Tezpur, Assam, India

We evaluated the impact of an AI (Artificial Intelligence) based software for automated interpretation of CT brain through a retrospective interrupted time series study at a rural hospital in Tezpur, India, that is managed by non-specialist physicians and supported by teleradiology services. We compared the diagnostic accuracy of the software to detect an abnormality against…



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