Indi Trehan

Adjunct Associate Professor, Epidemiology
Associate Professor, Pediatrics - Emergency Medicine
Adjunct Associate Professor, Global Health


BS University of California (Berkeley),



My major academic interests are in the development of a better understanding of the pathophysiology underlying chronic and acute childhood malnutrition, improving the diagnosis and treatment of malnourished children, and improvements in the diagnosis and management of tropical infectious diseases. The majority of my research experience in these domains has come in the conduct of large clinical trials in rural Malawi as well as in smaller hospital-based cohort studies to complement my clinical experience caring for children and adults in austere settings around the world. I serve as an advisor and consultant to UNICEF, Action Against Hunger, Médecins Sans Frontières, the Alliance for International Medical Action, and Friends Without a Border.

My clinical work abroad has spanned numerous countries and settings, including emergency care in Haiti, directing an Ebola Treatment Centre in Sierra Leone, and primary care in a Rohingya refugee camp in Bangladesh, but I am most passionate about training of local health care providers in evidence-based cost-effective care that maximizes survival and human potential. I took an academic sabbatical to manage clinical operations in rural Liberia for Partners in Health and then as the Medical Director and Executive Director of Lao Friends Hospital for Children in 2017-2019, before moving to Seattle in January 2020.

Research Interests

Child and Adolescent Health (incl. Pediatrics)
Child Mortality
Clinical Mentoring
Community Health Workers
Diarrheal Diseases
Education and Training
Emergency Medicine
Health Systems Strengthening and Human Resources Development
Infectious Diseases
Neglected Diseases, Tropical Medicine (incl. Parasites)
Nutrition, Clean Water, and Food Security
Trop. Med (incl. Parasites)

Recent Publications (PubMed)

A Predictive Model for Thiamine Responsive Disorders Among Infants and Young Children: Results from a Prospective Cohort Study in Lao People's Democratic Republic.
(2024 May)
J Pediatr 268(): 113961
Smith TJ, Arnold CD, Fischer PR, Trehan I, Hiffler L, Sitthideth D, Stein-Wexler R, Yeh J, Jones KS, Hampel D, Tancredi DJ, Schick MA, McBeth CN, Tan X, Allen LH, Sayasone S, Kounnavong S, Hess SY

Conflicts in Gaza and around the world create a perfect storm for infectious disease outbreaks.
PLOS Glob Public Health 4(2): e0002927
Kearney JE, Thiel N, El-Taher A, Akhter S, Townes DA, Trehan I, Pottinger PS

Effect of amoxicillin on the gut microbiome of children with severe acute malnutrition in Madarounfa, Niger: a retrospective metagenomic analysis of a placebo-controlled trial.
(2023 Nov)
Lancet Microbe 4(11): e931-e942
Schwartz DJ, Langdon A, Sun X, Langendorf C, Berthé F, Grais RF, Trehan I, Isanaka S, Dantas G

Emergency care interventions for paediatric severe acute respiratory infections in low- and middle-income countries: A systematic review and narrative synthesis.
(2023 Jun 9)
J Glob Health 13(): 04065
Relan P, Garbern SC, O'Reilly G, Bills CB, Schultz M, Kivlehan S, Trehan I, Becker TK

Sedation and Analgesia for Reduction of Pediatric Ileocolic Intussusception.
(2023 Jun 1)
JAMA Netw Open 6(6): e2317200
Poonai N, Cohen DM, MacDowell D, Mistry RD, Mintegi S, Craig S, Roland D, Miller M, Shavit I, Paediatric Emergency Research Networks (PERN) PAINT Study Group, Wang Y, Nager A, Heyming T, Burns R, Trehan I, Lipshaw M, Sulton C, Li J, Ojo A, Kelly S, Thornton M, Caperell K, Amoni I, Abrams A, Duong M, Wassem M, Davis A, Gravel J, Doyon Trottier E, Bar Am N, Thompson G, Sabhaney V, Meckler G, Jain R, Ali S, Bressan S, Zangardi T, Villa G, Giacalone M, Seiler M, Sahyoun C, Romano F, Bognar Z, Hajosi-Kalcakosz S, Amir L, Hachimi-Idrissi S, Pucuka Z, Zviedre A, Zeltina E, Phillips N, Borland M, O'Brien S, Marchant J, Kochar A, George S, Pennington V, Lyttle M, Browning J, McLoughlin A, Hartshorn S, Urooj C, Johnston L, Walton E, Subrahmanyam Puthucode D, Peacock P, Conroy J, Marañon R, Garcia S, Cahís N, Cámara-Otegui A, Gomez A, Carbonero M, Angelats-Romero C, Yock-Corrales A, Hualde G, Spigariol F, Donas A, Gübeli Linné C, Rocchi A, Pedrazzini A, Cozzi G, Barbi D, Baggio L, La Fauci G, Mauro A, Steimle M, Buonsenso D, Ugalde I, Nieva G, Harper C, Sforzi I, Jain S

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