Ulrike Peters

Research Professor, Epidemiology



PhD Nutrition, University of Kiel (Germany), 1998
MPH Epidemiology, University of North Carolina, 1999



Fred Hutchinson Cancer Research Center
Box 358080
1100 Fairview Ave N,M4-B402
PO Box 1024
Seattle, WA 98109

Research Interests

My research interest centers on the genetic and molecular epidemiology of common complex diseases, including cancer, obesity, type 2 diabetes, and cardiovascular diseases, as well as intermediate traits, including inflammation and metabolic measurements. Within well characterized and diverse study populations, we are studying the impact of common and rare genetic variants across the entire genome, as well as interactions between genetic variants and environmental factors (such as diet, exercise, smoking and aspirin use). We are increasingly bringing in functional genomic data to inform gene-environment interactions as well as rare variant testing. In addition, we are conducting a large-scale study to integrate the tumor and host genome to investigate associations of germline genetic, environmental risk factors and survival in relation to colorectal cancer subtypes defined by existing tumor characteristics as well as novel somatic mutations in colorectal cancer. A further interest of us is the translation of our findings into public health practice and clinical care. Accordingly, we have developed comprehensive risk prediction models that can personalize screening decisions.

Recent Publications (PubMed)

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids.
(2021 Sep 14)
Oncotarget 12(19): 1863-1877
Devall M, Dampier CH, Eaton S, Ali MW, Díez-Obrero V, Moratalla-Navarro F, Bryant J, Jennelle LT, Moreno V, Powell SM, Peters U, Casey G

Correction to: Multi-ethnic genome-wide association analyses of white blood cell and platelet traits in the Population Architecture using Genomics and Epidemiology (PAGE) Study.
(2021 Sep 13)
BMC Genomics 22(1): 656
Hu Y, Bien SA, Nishimura KK, Haessler J, Hodonsky CJ, Baldassari AR, Highland HM, Wang Z, Preuss M, Sitlani CM, Wojcik GL, Tao R, Graff M, Huckins LM, Sun Q, Chen MH, Mousas A, Auer PL, Lettre G, Blood Cell Consortium., Tang W, Qi L, Thyagarajan B, Buyske S, Fornage M, Hindorff LA, Li Y, Lin D, Reiner AP, North KE, Loos RJF, Raffield LM, Peters U, Avery CL, Kooperberg C

Bacterial translocation and microgap formation at a novel conical indexed implant abutment system for single crowns.
(2021 Aug 16)
Clin Oral Investig
Gehrke P, Burg S, Peters U, Beikler T, Fischer C, Rupp F, Schweizer E, Weigl P, Sader R, Smeets R, Schäfer S

Transcriptome-wide in vitro effects of aspirin on patient-derived normal colon organoids.
(2021 Aug 13)
Cancer Prev Res (Phila)
Devall MA, Drew DA, Dampier CH, Plummer SJ, Eaton S, Bryant J, Díez-Obrero V, Mo J, Kedrin D, Zerjav DC, Takacsi-Nagy O, Jennelle LT, Ali MW, Yilmaz OH, Moreno V, Powell SM, Chan AT, Peters U, Casey G

Association Between Smoking and Molecular Subtypes of Colorectal Cancer.
(2021 Aug)
JNCI Cancer Spectr 5(4): pkab056
Wang X, Amitay E, Harrison TA, Banbury BL, Berndt SI, Brenner H, Buchanan DD, Campbell PT, Cao Y, Chan AT, Chang-Claude J, Gallinger SJ, Giannakis M, Giles GG, Gunter MJ, Hopper JL, Jenkins MA, Lin Y, Moreno V, Nishihara R, Newcomb PA, Ogino S, Phipps AI, Sakoda LC, Schoen RE, Slattery ML, Song M, Sun W, Thibodeau SN, Toland AE, Van Guelpen B, Woods MO, Hsu L, Hoffmeister M, Peters U

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