Faculty

Ulrike Peters

Research Professor, Epidemiology

206-667-2450
upeters@fredhutch.org

Education

PhD Nutrition, University of Kiel (Germany), 1998
MPH Epidemiology, University of North Carolina, 1999

Contact

206-667-2450
upeters@fredhutch.org

Fred Hutchinson Cancer Research Center
Box 358080
1100 Fairview Ave N,M4-B402
PO Box 1024
Seattle, WA 98109

Research Interests

My research interest centers on the genetic and molecular epidemiology of common complex diseases, including cancer, obesity, type 2 diabetes, and cardiovascular diseases, as well as intermediate traits, including inflammation and metabolic measurements. Within well characterized and diverse study populations, we are studying the impact of common and rare genetic variants across the entire genome, as well as interactions between genetic variants and environmental factors (such as diet, exercise, smoking and aspirin use). We are increasingly bringing in functional genomic data to inform gene-environment interactions as well as rare variant testing. In addition, we are conducting a large-scale study to integrate the tumor and host genome to investigate associations of germline genetic, environmental risk factors and survival in relation to colorectal cancer subtypes defined by existing tumor characteristics as well as novel somatic mutations in colorectal cancer. A further interest of us is the translation of our findings into public health practice and clinical care. Accordingly, we have developed comprehensive risk prediction models that can personalize screening decisions.

Recent Publications (PubMed)

Body Mass Index and Molecular Subtypes of Colorectal Cancer.
(2022 Nov 29)
J Natl Cancer Inst
Murphy N, Newton CC, Song M, Papadimitriou N, Hoffmeister M, Phipps AI, Harrison TA, Newcomb PA, Aglago EK, Berndt SI, Brenner H, Buchanan DD, Cao Y, Chan AT, Chen X, Cheng I, Chang-Claude J, Dimou N, Drew D, Farris AB, French AJ, Gallinger S, Georgeson P, Giannakis M, Giles GG, Gruber SB, Harlid S, Hsu L, Huang WY, Jenkins MA, Laskar RS, Le Marchand L, Limburg P, Lin Y, Mandic M, Nowak JA, Obón-Santacana M, Ogino S, Qu C, Sakoda LC, Schoen RE, Southey MC, Stadler ZK, Steinfelder RS, Sun W, Thibodeau SN, Toland AE, Trinh QM, Tsilidis KK, Ugai T, Van Guelpen B, Wang X, Woods MO, Zaidi SH, Gunter MJ, Peters U, Campbell PT

Interactions between folate intake and genetic predictors of gene expression levels associated with colorectal cancer risk.
(2022 Nov 7)
Sci Rep 12(1): 18852
Haas CB, Su YR, Petersen P, Wang X, Bien SA, Lin Y, Albanes D, Weinstein SJ, Jenkins MA, Figueiredo JC, Newcomb PA, Casey G, Le Marchand L, Campbell PT, Moreno V, Potter JD, Sakoda LC, Slattery ML, Chan AT, Li L, Giles GG, Milne RL, Gruber SB, Rennert G, Woods MO, Gallinger SJ, Berndt S, Hayes RB, Huang WY, Wolk A, White E, Nan H, Nassir R, Lindor NM, Lewinger JP, Kim AE, Conti D, Gauderman WJ, Buchanan DD, Peters U, Hsu L

T cell-inflamed gene expression profile is associated with favorable disease-specific survival in non-hypermutated microsatellite-stable colorectal cancer patients.
(2022 Nov 7)
Cancer Med
Yin H, Harrison TA, Thomas SS, Sather CL, Koehne AL, Malen RC, Reedy AM, Wurscher MA, Hsu L, Phipps AI, Zaidi SHE, Newcomb PA, Peters U, Huyghe JR

Cultivation of Cryopreserved Human Dental Pulp Stem Cells-A New Approach to Maintaining Dental Pulp Tissue.
(2022 Sep 29)
Int J Mol Sci 23(19):
Wang W, Yan M, Aarabi G, Peters U, Freytag M, Gosau M, Smeets R, Beikler T

Transcriptomic Response to Calcium in Normal Colon Organoids is Impacted by Colon Location and Sex.
(2022 Oct 4)
Cancer Prev Res (Phila) 15(10): 679-688
Devall MAM, Dampier CH, Eaton S, Ali MW, Plummer SJ, Bryant J, Gauderman WJ, Peters U, Powell SM, Casey G

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