Faculty

Ulrike Peters

Research Professor, Epidemiology

206-667-2450
upeters@fhcrc.org

Education

PhD Nutrition, University of Kiel (Germany), 1998
MPH Epidemiology, University of North Carolina, 1999

Contact

206-667-2450
upeters@fhcrc.org

Fred Hutchinson Cancer Research Center
Box 358080
1100 Fairview Ave N,M4-B402
PO Box 1024
Seattle, WA 98109

Research Interests

My research interest centers on the genetic and molecular epidemiology of common complex diseases, including cancer, obesity, type 2 diabetes, and cardiovascular diseases, as well as intermediate traits, including inflammation and metabolic measurements. Within well characterized and diverse study populations, we are studying the impact of common and rare genetic variants across the entire genome, as well as interactions between genetic variants and environmental factors (such as diet, exercise, smoking and aspirin use). We are increasingly bringing in functional genomic data to inform gene-environment interactions as well as rare variant testing. In addition, we are conducting a large-scale study to integrate the tumor and host genome to investigate associations of germline genetic, environmental risk factors and survival in relation to colorectal cancer subtypes defined by existing tumor characteristics as well as novel somatic mutations in colorectal cancer. A further interest of us is the translation of our findings into public health practice and clinical care. Accordingly, we have developed comprehensive risk prediction models that can personalize screening decisions.

Recent Publications (PubMed)

Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis.
(2022 Jan 20)
J Natl Cancer Inst
Murphy N, Song M, Papadimitriou N, Carreras-Torres R, Langenberg C, Martin RM, Tsilidis KK, Barroso I, Chen J, Frayling T, Bull CJ, Vincent EE, Cotterchio M, Gruber SB, Pai RK, Newcomb PA, Perez-Cornago A, van Duijnhoven FJB, Van Guelpen B, Vodicka P, Wolk A, Wu AH, Peters U, Chan AT, Gunter MJ

Hemochromatosis risk genotype is not associated with colorectal cancer or age at its diagnosis.
(2020 Oct 22)
HGG Adv 1(1): 100010
Jarvik GP, Wang X, Fontanillas P, Kim E, Chanprasert S, Gordon AS, Bastarache L, Kowdley KV, Harrison T, Rosenthal EA, Stanaway IB, Bézieau S, Weinstein SJ, Newcomb PA, Casey G, Platz EA, Visvanathan K, Le Marchand L, Ulrich CM, Hardikar S, Li CI, van Duijnhoven FJB, Gsur A, Campbell PT, Moreno V, Vodička P, Brenner H, Chang-Claude J, Hoffmeister M, Slattery ML, Gunter MJ, Aglago EK, Castellví-Bel S, Kweon SS, Chan AT, Li L, Zheng W, Bishop DT, Giles GG, Rennert G, Offit K, Keku TO, Woods MO, Hampe J, Van Guelpen B, Gallinger SJ, de la Chapelle A, Hampel H, Berndt SI, Tangen CM, Lindblom A, Wolk A, Burnett-Hartman A, Wu AH, White E, 23andMe Research Team., Gruber SB, Jenkins MA, Mountain J, Peters U, Crosslin DR

Associating sleep problems with advanced cancer diagnosis, and immune checkpoint treatment outcomes: a pilot study.
(2022 Jan 16)
Support Care Cancer
Sillah A, Peters U, Watson NF, Tykodi SS, Hall ET, Silverman A, Malen RC, Thompson JA, Lee SM, Bhatia S, Veatch J, Warner J, Thornton T, Phipps AI

Risk Stratification for Early-Onset Colorectal Cancer Using a Combination of Genetic and Environmental Risk Scores: An International Multi-Center Study.
(2022 Jan 13)
J Natl Cancer Inst
Archambault AN, Jeon J, Lin Y, Thomas M, Harrison TA, Bishop DT, Brenner H, Casey G, Chan AT, Chang-Claude J, Figueiredo JC, Gallinger S, Gruber SB, Gunter MJ, Guo F, Hoffmeister M, Jenkins MA, Keku TO, Le Marchand L, Li L, Moreno V, Newcomb PA, Pai R, Parfrey PS, Rennert G, Sakoda LC, Lee JK, Slattery ML, Song M, Ko Win A, Woods MO, Murphy N, Campbell PT, Su YR, Lansdorp-Vogelaar I, Peterse EF, Cao Y, Zeleniuch-Jacquotte A, Liang PS, Du M, Corley DA, Hsu L, Peters U, Hayes RB

A Statistical Method for Association Analysis of Cell Type Compositions.
(2021 Dec)
Stat Biosci 13(3): 373-385
Huang L, Little P, Huyghe JR, Shi Q, Harrison TA, Yothers G, George TJ, Peters U, Chan AT, Newcomb PA, Sun W

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