Faculty

Ulrike Peters

Research Professor, Epidemiology

206-667-2450

Education

PhD Nutrition, University of Kiel (Germany), 1998
MPH Epidemiology, University of North Carolina, 1999

Contact

206-667-2450

Fred Hutch Cancer Center
Box 358080
1100 Fairview Ave N,M4-B402
PO Box 1024
Seattle, WA 98109

Research Areas

Research Interests

My research interest centers on the genetic and molecular epidemiology of common complex diseases, including cancer, obesity, type 2 diabetes, and cardiovascular diseases, as well as intermediate traits, including inflammation and metabolic measurements. Within well characterized and diverse study populations, we are studying the impact of common and rare genetic variants across the entire genome, as well as interactions between genetic variants and environmental factors (such as diet, exercise, smoking and aspirin use). We are increasingly bringing in functional genomic data to inform gene-environment interactions as well as rare variant testing. In addition, we are conducting a large-scale study to integrate the tumor and host genome to investigate associations of germline genetic, environmental risk factors and survival in relation to colorectal cancer subtypes defined by existing tumor characteristics as well as novel somatic mutations in colorectal cancer. A further interest of us is the translation of our findings into public health practice and clinical care. Accordingly, we have developed comprehensive risk prediction models that can personalize screening decisions.

Recent Publications (PubMed)

Investigating the association between anthropometry and colorectal cancer survival: a two-sample Mendelian randomization analysis.
(2025 Oct 14)
Int J Epidemiol 54(6):
Kanellopoulou A, Bouras E, Chan AT, Marchand LL, Wolk A, Wu AH, Gunter MJ, Nimptsch K, Haycock P, Lewis SJ, Martin RM, Zuber V, Phipps AI, Peters U, Van Duijnhoven FJB, Tsilidis KK
T-cell Subset Features and Distributions Evolve Across the Colorectal Precancer-Cancer Spectrum.
(2025 Nov 12)
Cancer Immunol Res
Takashima Y, Dias Costa A, Akimoto N, Ugai T, Bell P, Väyrynen JP, Hornick JL, Mino-Kenudson M, Zhong Y, Ugai S, Haruki K, Yao Q, Matsuda K, Higashioka M, Buchanan DD, Phipps AI, Peters U, Giannakis M, Song M, Chan AT, Fuchs CS, Nowak JA, Ogino S
Different diabetes types and pancreatic ductal adenocarcinoma: a Mendelian randomization and pathway/gene-set analysis.
(2025 Nov 9)
J Natl Cancer Inst
Zhang T, Hua X, Mohindroo C, Wang X, Dutta D, Liu J, Katta S, Li SA, Wang J, Antwi SO, Arslan AA, Beane Freeman LE, Bracci PM, Canzian F, Du M, Gallinger S, Goodman PJ, Katzke V, Kooperberg C, Le Marchand L, Neale RE, Patel AV, Perdomo S, Shu XO, Visvanathan K, Van Den Eeden SK, White E, Zheng W, Albanes D, Andreotti G, Bamlet WR, Brennan P, Buring JE, Chanock SJ, Chen Y, Darst B, Ferrari P, Giovannucci EL, Goggins M, Haiman C, Hassan M, Holly EA, Hung RJ, Jones MR, Kraft P, Kurtz RC, Malats N, Moore SC, Ng K, Oberg AL, Orlow I, Peters U, Porta M, Rabe KG, Rothman N, Sánchez MJ, Sesso HD, Silverman DT, Southey MC, Um CY, Yarmolinsky J, Yu H, Yuan C, Zhong J, Wolpin BM, Risch HA, Amundadottir LT, Klein AP, Yu K, Zhang H, Stolzenberg-Solomon RZ
Multiple polygenic score approach in colorectal cancer risk prediction.
(2025 Oct 30)
Sci Rep 15(1): 38006
Jiang SJ, Thomas M, Rosenthal EA, Phipps AI, Sakoda LC, van Duijnhoven FJB, Pellatt AJ, Avery CL, Berndt SI, Bishop DT, Castellví-Bel S, Chan AT, Grant RC, Gignoux C, Gsur A, Gunter MJ, Haiman CA, Hoffmeister M, Jarvik GP, Jenkins MA, Keku TO, Küry S, Lee JK, Marchand LL, Moreno V, Newcomb PA, Newton CC, Ogino S, Palmer JR, Pearlman R, Qu C, Schoen RE, Um CY, Van Guelpen B, Visvanathan K, Vymetalkova V, White E, Woods MO, Platz EA, Brenner H, Corley DA, Vogelaar IL, Hsu L, Peters U
Using gene-environment interactions to explore pathways for colorectal cancer risk.
(2025 Nov)
EBioMedicine 121(): 105964
Bouras E, Yu R, Kim AE, Markozannes G, Murphy N, Albanes D, Anderson LN, Barry EL, Berndt SI, Bishop DT, Brenner H, Burnett-Hartman A, Campbell PT, Carreras-Torres R, Chan AT, Cheng I, Devall MA, Diez-Obrero V, Dimou N, Drew DA, Gruber SB, Gsur A, Hoffmeister M, Hsu L, Huyghe JR, Kawaguchi E, Keku TO, Kundaje A, Küry S, Le Marchand L, Lewinger JP, Li L, Lynch BM, Moreno V, Morrison JL, Newton CC, Obón-Santacana M, Palmer JR, Papadimitriou N, Pellatt AJ, Peoples AR, Pharoah PDP, Platz EA, Qu C, Ruiz-Narvaez E, Mendez JS, Schoen RE, Stern MC, Thomas CE, Tian Y, Um CY, Visvanathan K, Vodicka P, Vymetalkova V, White E, Wolk A, Woods MO, Wu AH, Gunter MJ, Gauderman WJ, Peters U, Evangelou M, Tsilidis KK
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