Holly R Harris
Affiliate Associate Professor, Epidemiology
Affiliate Associate Professor, Obstetrics and Gynecology
206-667-2712
hharris@fredhutch.org
Education
ScD Harvard T.H. Chan,
MPH University of Southern California, 2005
BA Macalester College, 2000
Contact
206-667-2712
hharris@fredhutch.org
Box M4-B859
Program in Epidemiology, Division of Public Health Sciences
1100 Fairview Avenue North
Seattle, WA 98109
Research Areas
Research Interests
I am broadly interested in the impact of lifestyle, nutrition, and genetic factors on women’s health. Specifically, I have focused on ovarian and breast cancer, as well as on hormonally related conditions that have shared reproductive risk factors with these diseases, including endometriosis and uterine fibroids. Much of my research to date has focused on understanding the role of the potentially modifiable risk factors of diet and lifestyle on the risk of these conditions. A more recent facet of my research is to explore the interrelatedness of these conditions and their shared risk factors. As ovarian cancer is rare, I am particularly interested in identifying women, such as those with endometriosis, who may be at higher risk because these women may benefit from screening modalities for ovarian cancer which are currently not appropriate for population-based use. Identification of women at high risk for ovarian cancer and breast cancer is also important as it allows for targeted prevention strategies and can guide clinical decisions regarding frequency of screening and chemoprevention strategies for both of these cancers. Finally, understanding the influence of genetic factors, both alone or as a part of gene-environment interactions may facilitate prevention and help identify women most at risk for ovarian and breast cancer.
Recent Publications (PubMed)
(2026 Apr 1)
JAMA Netw Open 9(4): e268641
Williamson MR, Whitsel EA, Smith RL, Collins JM, Stewart JD, Jung SY, Harris HR, Feiler MO, Manson JE, Qi L, Schwartz GG
(2026 Apr 1)
Nat Commun
Zwimpfer TA, Fereday S, Pandey A, Ariyaratne D, Jayawardana MW, Twomey L, Laumont CM, Kennedy CJ, Bolithon A, Meagher NS, Milne K, Hamilton P, Alsop J, Antoniou AC, Au-Yeung G, Beckmann MW, Berrington de Gonzalez A, Bisinotto C, Blome F, Bodelon C, Boros J, Brand AH, Carney ME, Cazorla-Jiménez A, Chiu DS, Christie EL, Chudecka-Głaz A, Coulson P, Cushing-Haugen KL, Cybulski C, Darcy KM, David C, Davidson T, Ekici AB, Elishaev E, Emons J, Engler T, Farrell R, Fischer A, García-Closas M, Gentry-Maharaj A, Ghatage P, Glasspool R, Harter P, Hartkopf AD, Hartmann A, Heikaus S, Hernandez BY, Hettiaratchi A, Heublein S, Huntsman DG, Jimenez-Linan M, Jones ME, Kang E, Kaznowska E, Kluz T, Kommoss FKF, Konecny G, Kruitwagen RFPM, Kwon J, Lambrechts D, Lee CH, Lester J, Leung SCY, Leung Y, Linder A, Lissowska J, Loverix L, Lubiński J, Mateoiu C, McNeish IA, Moubarak M, Nelson GS, Nevins N, Olawaiye AB, Olbrecht S, Orsulic S, Osorio A, Quinn CM, Mohan GR, Ray-Coquard I, Rodríguez-Antona C, Roxburgh P, Ruebner M, Salfinger SG, Samra S, Schoemaker MJ, Sinn HP, Sonke GS, Steele L, Stewart CJR, Talhouk A, Tan A, Tarney CM, Taylor SE, Van de Vijver KK, van der Aa MA, Van Gorp T, Van Nieuwenhuysen E, Van-Wagensveld L, Wahner-Hendrickson AE, Walter C, Wang C, Welz J, Wentzensen N, Wilkens LR, Winham SJ, Winterhoff B, Anglesio MS, Berchuck A, Candido Dos Reis FJ, Cohen PA, Conrads TP, Crowe P, Doherty JA, Fasching PA, Fortner RT, García MJ, Gayther SA, Goodman MT, Gronwald J, Harris HR, Heitz F, Horlings HM, Karlan BY, Kelemen LE, Larry Maxwell G, Menon U, Modugno F, Neuhausen SL, Schildkraut JM, Staebler A, Sundfeldt K, Swerdlow AJ, Vergote I, Wu AH, Brenton JD, Pharoah PDP, Pearce CL, Pike MC, Goode EL, Ramus SJ, Köbel M, Nelson BH, DeFazio A, Friedlander ML, Bowtell DDL, Garsed DW
(2026 Mar 20)
Obesity (Silver Spring)
Blew RM, Ziller SG, Odegaard AO, Caan BJ, Chen Z, Roe DJ, Manson JE, Rohan TE, Felix AS, Harris HR, Luo J, Lane DS, Bea JW
(2026 Feb 18)
Int J Epidemiol 55(2):
Hurwitz LM, O'Brien KM, Townsend MK, Reid BM, Fridley BL, Fan W, Schabath MB, Bodelon C, Chan AT, Fortner RT, Håkansson N, Harris HR, Lacey JV Jr, Liao LM, Merritt MA, Patel AV, Poynter JN, Robien K, Sandler DP, Wentzensen N, Wolk A, Zheng W, Tworoger SS, Trabert B
(2026 Jan 8)
Fertil Steril
Thornburgh S, Farland LV, Harris HR, Sonneville KR, Neblett MF 2nd, Field AE, Chavarro JE, Missmer SA, Gaskins AJ
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