Faculty

Holly Harris

Affiliate Assistant Professor, Epidemiology

206-667-2712
hharris@fredhutch.org

Education

ScD Harvard T.H. Chan,
MPH University of Southern California, 2005
BA Macalester College, 2000

Contact

206-667-2712
hharris@fredhutch.org

Fred Hutchinson Cancer Research Center
Box M4-B859
Program in Epidemiology, Division of Public Health Sciences
1100 Fairview Avenue North
Seattle, WA 98109

Research Interests

I am broadly interested in the impact of lifestyle, nutrition, and genetic factors on women’s health. Specifically, I have focused on ovarian and breast cancer, as well as on hormonally related conditions that have shared reproductive risk factors with these diseases, including endometriosis and uterine fibroids. Much of my research to date has focused on understanding the role of the potentially modifiable risk factors of diet and lifestyle on the risk of these conditions. A more recent facet of my research is to explore the interrelatedness of these conditions and their shared risk factors. As ovarian cancer is rare, I am particularly interested in identifying women, such as those with endometriosis, who may be at higher risk because these women may benefit from screening modalities for ovarian cancer which are currently not appropriate for population-based use. Identification of women at high risk for ovarian cancer and breast cancer is also important as it allows for targeted prevention strategies and can guide clinical decisions regarding frequency of screening and chemoprevention strategies for both of these cancers. Finally, understanding the influence of genetic factors, both alone or as a part of gene-environment interactions may facilitate prevention and help identify women most at risk for ovarian and breast cancer.

Recent Publications (PubMed)

Pesticide residue intake from fruit and vegetable consumption and risk of laparoscopically-confirmed endometriosis.
(2022 May 19)
F S Sci
Garzia NA, Cushing-Haugen K, Chiu YH, Sandoval-Insausti H, Chavarro JE, Missmer SA, Harris HR

Glycemic Index, Glycemic Load, Fiber, and Gluten Intake and Risk of Laparoscopically-Confirmed Endometriosis in Premenopausal Women.
(2022 May 12)
J Nutr
Schwartz NRM, Afeiche MC, Terry KL, Farland LV, Chavarro JE, Missmer SA, Harris HR

Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk.
(2022 May)
Eur J Hum Genet 30(5): 630-631
Dareng EO, Tyrer JP, Barnes DR, Jones MR, Yang X, Aben KKH, Adank MA, Agata S, Andrulis IL, Anton-Culver H, Antonenkova NN, Aravantinos G, Arun BK, Augustinsson A, Balmaña J, Bandera EV, Barkardottir RB, Barrowdale D, Beckmann MW, Beeghly-Fadiel A, Benitez J, Bermisheva M, Bernardini MQ, Bjorge L, Black A, Bogdanova NV, Bonanni B, Borg A, Brenton JD, Budzilowska A, Butzow R, Buys SS, Cai H, Caligo MA, Campbell I, Cannioto R, Cassingham H, Chang-Claude J, Chanock SJ, Chen K, Chiew YE, Chung WK, Claes KBM, Colonna S, GEMO Study Collaborators., GC-HBOC Study Collaborators., EMBRACE Collaborators., Cook LS, Couch FJ, Daly MB, Dao F, Davies E, de la Hoya M, de Putter R, Dennis J, DePersia A, Devilee P, Diez O, Ding YC, Doherty JA, Domchek SM, Dörk T, du Bois A, Dürst M, Eccles DM, Eliassen HA, Engel C, Evans GD, Fasching PA, Flanagan JM, Fortner RT, Machackova E, Friedman E, Ganz PA, Garber J, Gensini F, Giles GG, Glendon G, Godwin AK, Goodman MT, Greene MH, Gronwald J, OPAL Study Group., AOCS Group., Hahnen E, Haiman CA, Håkansson N, Hamann U, Hansen TVO, Harris HR, Hartman M, Heitz F, Hildebrandt MAT, Høgdall E, Høgdall CK, Hopper JL, Huang RY, Huff C, Hulick PJ, Huntsman DG, Imyanitov EN, KConFab Investigators., HEBON Investigators., Isaacs C, Jakubowska A, James PA, Janavicius R, Jensen A, Johannsson OT, John EM, Jones ME, Kang D, Karlan BY, Karnezis A, Kelemen LE, Khusnutdinova E, Kiemeney LA, Kim BG, Kjaer SK, Komenaka I, Kupryjanczyk J, Kurian AW, Kwong A, Lambrechts D, Larson MC, Lazaro C, Le ND, Leslie G, Lester J, Lesueur F, Levine DA, Li L, Li J, Loud JT, Lu KH, Lubiński J, Mai PL, Manoukian S, Marks JR, Matsuno RK, Matsuo K, May T, McGuffog L, McLaughlin JR, McNeish IA, Mebirouk N, Menon U, Miller A, Milne RL, Minlikeeva A, Modugno F, Montagna M, Moysich KB, Munro E, Nathanson KL, Neuhausen SL, Nevanlinna H, Yie JNY, Nielsen HR, Nielsen FC, Nikitina-Zake L, Odunsi K, Offit K, Olah E, Olbrecht S, Olopade OI, Olson SH, Olsson H, Osorio A, Papi L, Park SK, Parsons MT, Pathak H, Pedersen IS, Peixoto A, Pejovic T, Perez-Segura P, Permuth JB, Peshkin B, Peterlongo P, Piskorz A, Prokofyeva D, Radice P, Rantala J, Riggan MJ, Risch HA, Rodriguez-Antona C, Ross E, Rossing MA, Runnebaum I, Sandler DP, Santamariña M, Soucy P, Schmutzler RK, Setiawan VW, Shan K, Sieh W, Simard J, Singer CF, Sokolenko AP, Song H, Southey MC, Steed H, Stoppa-Lyonnet D, Sutphen R, Swerdlow AJ, Tan YY, Teixeira MR, Teo SH, Terry KL, Terry MB, OCAC Consortium., CIMBA Consortium., Thomassen M, Thompson PJ, Thomsen LCV, Thull DL, Tischkowitz M, Titus L, Toland AE, Torres D, Trabert B, Travis R, Tung N, Tworoger SS, Valen E, van Altena AM, van der Hout AH, Van Nieuwenhuysen E, van Rensburg EJ, Vega A, Edwards DV, Vierkant RA, Wang F, Wappenschmidt B, Webb PM, Weinberg CR, Weitzel JN, Wentzensen N, White E, Whittemore AS, Winham SJ, Wolk A, Woo YL, Wu AH, Yan L, Yannoukakos D, Zavaglia KM, Zheng W, Ziogas A, Zorn KK, Kleibl Z, Easton D, Lawrenson K, DeFazio A, Sellers TA, Ramus SJ, Pearce CL, Monteiro AN, Cunningham J, Goode EL, Schildkraut JM, Berchuck A, Chenevix-Trench G, Gayther SA, Antoniou AC, Pharoah PDP

The epidemiology of uterine fibroids: Where do we go from here?
(2022 Apr)
Fertil Steril 117(4): 841-842
Harris HR, Petrick JL, Rosenberg L

The impact of the COVID-19 pandemic on older women in the Women's Health Initiative.
(2022 Mar 3)
J Gerontol A Biol Sci Med Sci
VoPham T, Harris HR, Tinker LF, Manson JAE, Meliker JR, Wassertheil-Smoller S, Shadyab AH, Saquib N, Anderson GL, Shumaker SA

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