Faculty

Holly R Harris

Affiliate Associate Professor, Epidemiology

206-667-2712

Education

ScD Harvard T.H. Chan,
MPH University of Southern California, 2005
BA Macalester College, 2000

Contact

206-667-2712

Fred Hutchinson Cancer Research Center
Box M4-B859
Program in Epidemiology, Division of Public Health Sciences
1100 Fairview Avenue North
Seattle, WA 98109

Research Interests

I am broadly interested in the impact of lifestyle, nutrition, and genetic factors on women’s health. Specifically, I have focused on ovarian and breast cancer, as well as on hormonally related conditions that have shared reproductive risk factors with these diseases, including endometriosis and uterine fibroids. Much of my research to date has focused on understanding the role of the potentially modifiable risk factors of diet and lifestyle on the risk of these conditions. A more recent facet of my research is to explore the interrelatedness of these conditions and their shared risk factors. As ovarian cancer is rare, I am particularly interested in identifying women, such as those with endometriosis, who may be at higher risk because these women may benefit from screening modalities for ovarian cancer which are currently not appropriate for population-based use. Identification of women at high risk for ovarian cancer and breast cancer is also important as it allows for targeted prevention strategies and can guide clinical decisions regarding frequency of screening and chemoprevention strategies for both of these cancers. Finally, understanding the influence of genetic factors, both alone or as a part of gene-environment interactions may facilitate prevention and help identify women most at risk for ovarian and breast cancer.

Recent Publications (PubMed)

Early-Life Exposures and Odds of Adenomyosis: A Population-Based Case-Control Study.
(2025 Jan 7)
Paediatr Perinat Epidemiol
Hall MS, Harris HR, As-Sanie S, Upson K

Endometriosis and Ovarian Cancer.
(2024 Dec 24)
JAMA 332(24): 2116-2117
Terry KL, Harris HR, Missmer SA

Immunological and molecular features of the tumor microenvironment of long-term survivors of ovarian cancer.
(2024 Oct 29)
J Clin Invest 134(24):
Nelson BH, Hamilton P, Phung MT, Milne K, Harris B, Thornton S, Stevens D, Kalaria S, Singh K, Laumont CM, Moss E, Alimujiang A, Meagher NS, Bolithon A, Fereday S, Kennedy CJ, Hendley J, Ariyaratne D, Alsop K, Traficante N, Goode EL, Karnezis A, Shen H, Richardson J, McKinnonDeurloo C, Chase A, Grout B, Doherty JA, Harris HR, Cushing-Haugen KL, Anglesio M, Heinze K, Huntsman D, Talhouk A, Hanley GE, Alsop J, Jimenez-Linan M, Pharoah PD, Boros J, Brand AH, Harnett PR, Sharma R, Hecht JL, Sasamoto N, Terry KL, Karlan B, Lester J, Carney ME, Goodman MT, Hernandez BY, Wilkens LR, Behrens S, Turzanski Fortner R, Fasching PA, Bisinotto C, Candido Dos Reis FJ, Ghatage P, Köbel M, Elishaev E, Modugno F, Cook L, Le N, Gentry-Maharaj A, Menon U, García MJ, Rodriguez-Antona C, Farrington K, Kelemen LE, Kommoss S, Staebler A, Garsed DW, Brenton JD, Piskorz AM, Bowtell DD, DeFazio A, Ramus SJ, Pike MC, Pearce CL

History of Infertility and Risk of Endometrial Cancer in the Women's Health Initiative.
(2024 Dec 2)
Cancer Epidemiol Biomarkers Prev 33(12): 1683-1689
Harris HR, Saboda K, Thomson CA, Saquib N, Shadyab AH, Schnatz PF, Robles-Morales R, Qi L, Roe DJ, Farland LV

Menopausal Hormone Therapy and Ovarian and Endometrial Cancers: Long-Term Follow-Up of the Women's Health Initiative Randomized Trials.
(2024 Oct 20)
J Clin Oncol 42(30): 3537-3549
Chlebowski RT, Aragaki AK, Pan K, Haque R, Rohan TE, Song M, Wactawski-Wende J, Lane DS, Harris HR, Strickler H, Kauntiz AM, Runowicz CD

Show complete publication list

In the News

No news articles at this time.