Department of Epidemiology

MS


December 21, 2023

Historical redlining and survival among children, adolescents, and young adults with cancer diagnosed between 2007-2019 in Seattle/Tacoma

Historic redlining has been associated with inferior survival in adult-onset cancers, however whether there is an association in pediatric, adolescent, and young-adult-onset cancers is unknown. Methods: Cancer cases among individuals living in Seattle and Tacoma between 2007-2019 were identified via Cancer Surveillance System. Case redlining status was determined using Home Owner Loans Corporation (HOLC) data…


Outcomes of Kidney Transplantation Among Undocumented Immigrants in the United States

Kidney transplantation is the optimal treatment for end-stage kidney disease (ESKD), but undocumented immigrants in the United States are often excluded from health insurance coverage necessary to undergo kidney transplantation. Arguments in favor of such policies are based on concern that undocumented immigrants face increased risk for graft loss, but transplant outcomes in this population…


Association Between Isolation Source, Clonal Composition, and Antibiotic Resistance Genes in Escherichia coli Samples Collected in Washington State

The growing prevalence of antimicrobial resistance (AMR) represents a significant global health problem. AMR is caused by the overuse of antibiotics in humans, animals, and the environment, making it necessary to apply a One Health approach to address the problem. Methods: We used whole genome sequencing (WGS) data from 1,449 Escherichia coli (E. coli) isolates…


Did California’s 2020 Medi-Cal Expansion Improve Health Insurance Coverage and Mental Health Outcomes Among Young Adults Without US Citizenship? A Population-based, Quasi-Experimental Study

In 2020, California became one of the first states to expand Medicaid (Medi-Cal) to low-income young adults, irrespective of US citizenship. The primary aim of this study was to assess whether California’s 2020 Young Adult Medi-Cal expansion improved healthcare access and mental health outcomes among low-income (<200% Federal Poverty Line) young adults aged 18-25 who…


Prioritizing Out-of-Care Case Investigations in King County, Washington

Health departments need to investigate cases of people with HIV who appear to be out of care but often have insufficient resources to investigate all cases and need a way to prioritize investigations. Methods: In this retrospective cohort analysis, we used classification and regression tree (CART) methodology to develop and validate a decision algorithm for…


Can Artificial Intelligence based Automated CT Brain Interpretation Software help Early Clinical Decision Making for Stroke Patients in Real World Resource Limited Settings with Non-Specialist Physicians? An Interrupted Time Series Study from Tezpur, Assam, India

We evaluated the impact of an AI (Artificial Intelligence) based software for automated interpretation of CT brain through a retrospective interrupted time series study at a rural hospital in Tezpur, India, that is managed by non-specialist physicians and supported by teleradiology services. We compared the diagnostic accuracy of the software to detect an abnormality against…


Hemoptysis and serious outcomes in cystic fibrosis

Hemoptysis is a common and important complication in persons with cystic fibrosis (PwCF). Despite this, there is limited literature on the impact of hemoptysis on contemporary cystic fibrosis (CF) outcomes. We sought to evaluate whether hemoptysis increases risk of lung transplant or death without transplant in PwCF. We reviewed a dataset of PwCF ages 12…


Predictors of Disease Activity in Juvenile Idiopathic Arthritis at 12 and 24 Months After Diagnosis

Identification of characteristics associated with risk of active disease in Juvenile Idiopathic Arthritis (JIA) could inform treatment strategies early in the disease state. This study evaluates JIA disease activity outcomes and patient characteristics associated with active disease at 12- and 24-months post diagnosis from a single large US center. Methods: Disease activity status at 12-…


Association Between Prediagnostic Cigarette Smoking and Colorectal Cancer Survival by Molecular Subtypes and Age-onset Status.

In the United States, colorectal cancer (CRC) remains the third most commonly diagnosed malignancy in both men and women, and approximately 36% of CRC patients die within the first five years after diagnosis. Several factors are known to affect the survival of CRC patients, including smoking history; however, it is unclear whether previously-observed associations between…


December 21, 2022

Heart Rate Variability and Autonomic Function: A Study of Adolescents with Chronic Abdominal Pain and Healthy Adolescents

Background: Chronic abdominal pain is often accompanied by autonomic dysfunction. It is hypothesized that dysregulation of the autonomic nervous system (ANS) results in poorer physiological modulation to physical and psychological stress in the context of persistent pain. Research in adults with chronic pain conditions identified decreased parasympathetic activation using heart rate variability (HRV), as a…



Previous page Next page