MS
December 26, 2023
Associations Between Structural and Social Determinants of Health with Pediatric Surgical Site Infections
Determine if disparities exist in surgical site infections (SSI) for pediatric patients from minoritized language and racial and ethnic groups, and for those with a public insurance payor. Design, Setting, and Participants: This single-center cohort study retrospectively examined outcomes of patients undergoing eligible inpatient and outpatient surgical procedures from October 1, 2015 to September 30,…
Predictors of Mortality and Discharge Location for Patients Supported by Venoarterial Extracorporeal Membrane Oxygenation
Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a form of advanced life support that is increasingly used to treat cardiac or pulmonary failure, however morbidity and mortality for patients supported by VA-ECMO remains high. Elucidation of predictors of mortality and discharge location for survivors may aid clinicians, patients, and families in prognostication for patients supported by…
KRAS Codon 12 and Codon 13 Mutations in Relation to Overall Survival among Colorectal Cancer Patients: A Systematic Review and Meta-Analysis
Oncogenic mutations in KRAS codon 12 and codon 13 within exon 2 are frequently occurring mutations in colorectal cancer (CRC). However, the existing published data on the association of KRAS codon 12 and codon 13 mutations on the survival of CRC patients remains inconclusive. To address this, we conducted a systematic PubMed search and meta-analysis….
Pregnancy and cervical cancer: a retrospective study of the associations of age at first pregnancy and parity with non-invasive and invasive cervical lesions among HIV-negative women in Senegal
Cervical cancer is the leading cause of cancer-related deaths in Senegal. Senegal’s cervical cancer prevention strategy has prioritized vaccinating young girls with human papillomaviruses (HPV) vaccines, but not screening of older women. There is limited knowledge about the roles of age at first pregnancy (AFP) and parity in developing cervical intra-epithelial lesions (CIN) and invasive…
December 22, 2023
Reliability of IgG serum antibodies, the electronic health record, and self-report in estimating urogenital and extragenital Chlamydia trachomatis infections in men who have sex with men
Few studies have examined the systemic antibody response in extragenital Chlamydia trachomatis (CT) infections. We estimate seroprevalence of IgG serum antibodies to CT among a cohort of men who have sex with men (MSM) with and without current infections stratified by anatomic site. We also examine the reliability of IgG serum antibodies, the electronic health…
Cofactors of neonatal mortality and hospitalization in western Kenya
Although global neonatal mortality has been declining over the past several decades, it remains a major contributor to infant and childhood mortality rates. Determining the biological, psychosocial, and behavioral cofactors of neonatal mortality and hospitalization can help identify high-risk populations and behaviors associated with adverse neonatal health outcomes and will be relevant to research and…
Factors associated with costly and potentially burdensome hospital care among patients with dementia and respiratory failure
Understanding contributors to costly and potentially burdensome hospital care for critically ill patients with dementia is of interest to healthcare systems and may facilitate efforts to ensure care is concordant with patients’ goals. We conducted an electronic health record (EHR)-based retrospective cohort study of 298 adults with dementia identified using International Classification of Diseases codes….
Patterns of acute kidney injury and functional outcome scores in pediatric patients hospitalized with acute respiratory failure
Acute kidney injury (AKI) is diagnosed in up to 30% of children admitted to pediatric intensive care units (PICU) and is strongly associated with morbidity and mortality. In recent years, there has been an increased focus on patient-centered outcomes and quality of life among survivors of AKI. One study of pediatric sepsis patients with AKI…
December 21, 2023
Historical redlining and survival among children, adolescents, and young adults with cancer diagnosed between 2007-2019 in Seattle/Tacoma
Historic redlining has been associated with inferior survival in adult-onset cancers, however whether there is an association in pediatric, adolescent, and young-adult-onset cancers is unknown. Methods: Cancer cases among individuals living in Seattle and Tacoma between 2007-2019 were identified via Cancer Surveillance System. Case redlining status was determined using Home Owner Loans Corporation (HOLC) data…
Outcomes of Kidney Transplantation Among Undocumented Immigrants in the United States
Kidney transplantation is the optimal treatment for end-stage kidney disease (ESKD), but undocumented immigrants in the United States are often excluded from health insurance coverage necessary to undergo kidney transplantation. Arguments in favor of such policies are based on concern that undocumented immigrants face increased risk for graft loss, but transplant outcomes in this population…
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