Department of Epidemiology

MPH


January 14, 2021

Evaluating Measures of HIV Risk Perception with a Mixed Method Approach Among Adolescent Girls and Young Women Using PrEP in Kenya

Introduction: Pre-exposure prophylaxis (PrEP) for HIV prevention is a promising HIV prevention option for young African women. The evidence of effective PrEP use in this population group is mixed, and has been tied to poor adherence. Discordance between assessed HIV risk and the actual experience of risk may underlie the dissonance observed between epidemiologic risk,…


Prenatal Exposure to Ambient Air Pollution, Gestational Weight Gain, and Offspring Birth Weight

Background. Ankylosing spondylitis (AS) patients have elevated cardiovascular (CV) morbidity and mortality compared to general population comparators of the same age and sex. Although obesity is an important and modifiable CV risk factor, there are few prospective studies addressing the impact of higher body mass index (BMI) on clinical outcomes in AS. The aim of…


Adverse Childhood Experiences and Systemic Inflammation in Adults in the United States

Background and significance: Adverse childhood experiences (ACEs) are associated with poor behavioral and physical health outcomes in adulthood. Though not fully elucidated, systemic inflammation is one mechanism through which ACEs are thought to affect health outcomes in adulthood. The objective of this study was to assess the relationship between ACEs and systemic inflammation and if…


Validity of Self-reported HPV Vaccination History in 18-26 Year Old Men Who Have Sex with Men, 2016-2018

Background Since 2011, human papillomavirus (HPV) vaccination has been recommended for men who have sex with men (MSM) through age 26 to prevent infection with the HPV types most commonly associated with cancer. Accurate estimates of HPV vaccine coverage are needed to monitor coverage and impact of HPV vaccine over time. We assessed the validity…


Social Support Regarding Abortion Decision and Mental Health Outcomes at Time of Seeking Abortion Services

Background: While the relationship between social support and mental health in the general population is well established, little is known about the role of social support, particularly decision support, in the mental health of people seeking abortion services. The objective of this study was to investigate the association between social support regarding abortion decision and…


Correlates of HIV status non-disclosure by pregnant women living with HIV to their male partners in Uganda: a cross-sectional study

Background: HIV status disclosure by pregnant women living with HIV (PWLHIV) to their male partners is associated with improved maternal and infant outcomes. Understanding relationship factors associated with non-disclosure of HIV status by PWLHIV to their partners can inform the design of interventions to facilitate status disclosure. Methods: We conducted a cross-sectional study using enrollment…


Local-level Association of Social Deprivation and Serious Injuries in Washington State: An Ecological Cross-sectional Study

Background Injuries, a major source of morbidity and mortality, are associated with social determinants of health. To inform strategic prioritization and targeting of injury prevention resources, there is a need to better understand the relationship between specific community-level factors and serious injuries. Methods We conducted an ecological cross-sectional study in ZIP Code Tabulation Areas (ZCTAs)…


January 12, 2021

Non-gonococcal urethritis and its relationship to three novel bacterial vaginosis (BV) associated bacteria

Objective: Non-gonococcal urethritis (NGU) is the most common urethral syndrome in the United States, yet up to 50% of cases are of unknown etiology. Bacterial-vaginosis associated bacteria (BVAB), highly predictive of BV in cisgender women, have been detected in cisgender men and may explain some cases of NGU. We sought to determine the frequency and…


An evaluation of the performance characteristics of World Health Organization syndromic management for C. trachomatis and N. gonorrhoeae infections among female sex workers in Mombasa, Kenya

Abstract An evaluation of the performance characteristics of World Health Organization syndromic management for C. trachomatis and N. gonorrhoeae infections among female sex workers in Mombasa, Kenya Gregory Zane Chair of the Supervisory Committee: Dr. Jennifer Balkus Department of Epidemiology Objectives: To assess the performance characteristics of the World Health Organization’s (WHO) syndromic surveillance algorithms…


Weight gain following antiretroviral therapy (ART) initiation in ART-naive people living with HIV in the current treatment era

Objectives We evaluated weight change among people living with HIV (PLWH) initiating antiretroviral therapy (ART) in the current treatment era. Methods Between 2012-2019, in 8 Centers for AIDS Research Network of Integrated Clinical Systems (CNICS) sites, we identified 3232 ART-naïve PLWH starting 3-drug ART, including efavirenz (EFV), rilpivirine (RPV), atazanavir (ATV), darunavir (DRV), raltegravir (RAL),…



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