Graduate
November 18, 2020
Following a Firearm Injury: Recidivism and Behavior Change
Firearm injuries remain an important and understudied public health problem. Besides the high cost of injury care, loss of work, potential need for long term care and emotional trauma for the individual injured, firearm injuries pose unique harm to the larger community as well. Individuals with a history of firearm injury are at substantially higher…
Early childhood diarrhea and growth among HIV-exposed, uninfected infants in Kenya
BACKGROUND Diarrhea and poor linear growth are leading causes of childhood morbidity and mortality in low- and middle- income countries. While global childhood mortality has been significantly reduced in the past decades, further reductions will likely require a better understanding of the causes of and relationship between diarrhea and linear growth in vulnerable populations. The…
What’s PrEP?: Examining Factors Associated with PrEP Peer Navigator Acceptability among Black and Latinx MSM in Western Washington
B ackground: HIV PrEP (pre-exposure prophylaxis) is underutilized among Black and Latinx men who have sex with men (MSM). We aimed to estimate interest in peer navigation for PrEP services among minority MSM in Western Washington. Methods: HIV-negative participants aged ≥16 identifying as Black or Latinx MSM completed a REDCap survey in English or Spanish….
Evaluating risk factors and synergistic effects of two common HIV-1 coinfections: schistosomiasis and trichomoniasis
INTRODUCTION HIV-1 coinfections have long been suspected of catalyzing the HIV-1 epidemic by increasing HIV-1 transmission or acquisition risk. The geographical distribution of coinfections may explain why some regions have been more heavily impacted by HIV-1. The primary objective of this dissertation was to expand our understanding of two common HIV-1 coinfections that have been…
A Concurrent and Longitudinal Analysis of Teacher Support, Stressful Life Events, and Depressive Symptoms in Early Adolescence
Introduction: Depression is a major public health issue globally and is associated with a variety of undesirable outcomes. This analysis examines the concurrent and prospective associations between teacher social support and depressive symptoms in middle school-aged youth and the ways that this association may depend on stressful life events and sex, as informed by the…
The role of individual and community level social and cultural connectedness in modifying the effect of childhood adversity on anxiety and depression in American Indian college students
BACKGROUND While causes of anxiety and depression are multifactorial, chronic and acute stress experiences play an important role. Adverse Childhood Experiences (ACEs), are sources of childhood stress for which a dose-response relationship with anxiety and depression symptoms across the lifespan has been well established. American Indian and Alaskan Natives (AIANs) experience significantly more ACEs compared…
Effects of Washington’s opioid prescribing rules for chronic, non-cancer pain management on opioid overdose mortality and pharmaceutical opioid distribution: 1999-2017
Background Since the 1990s, the opioid crisis has affected individuals and communities across the United States. National and statewide comprehensive efforts to address the problem include policies to prevent opioid addiction, identify opioid-addicted individuals, and provide effective treatment. In Washington state, in response to rising prescription opioid-related overdose deaths, the legislature passed the Engrossed Substitute…
Assessment of Repeat HIV Testing and Utilization of HIV Self-Testing to Increase Repeat Testing Amongst Pregnant and Postpartum Women in Kisumu County, Kenya
University of Washington Abstract Assessment of Repeat HIV Testing and Utilization of HIV Self-Testing to Increase Repeat Testing Amongst Pregnant and Postpartum Women in Kisumu County, Kenya Patrick Oyaro Owiti Chair of the Supervisory Committee: Jared Baeten, Department of Epidemiology Repeat HIV testing of pregnant and postpartum women is key to prevention of mother-to-child transmission…
Plasma Amyloid, Inflammatory Markers, and Risk of Dementia in the Ginkgo Evaluation of Memory Study
Most individuals with dementia have mixed neurodegenerative and vascular pathologies that may interact to accelerate cognitive decline. Prior studies have shown that two vascular inflammatory markers (pentraxin 3 and serum amyloid P) and plasma amyloid are associated with dementia, though results have been inconsistent. Using weighted Cox proportional hazards regression, we evaluated the joint associations…
Antidepressant medication continuation during pregnancy and perinatal outcomes, including gestational weight gain, gestational diabetes, and birth weight
BACKGROUND Every year, approximately 7–8% of pregnant women in the US (~300,000 women) use antidepressants. Use of certain antidepressants in non-pregnant populations has been associated with weight loss, whereas others have been associated with weight gain; in pregnant women, the association of antidepressant use and gestational weight gain has not been thoroughly investigated. Some studies…
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