Faculty

Debby W. Tsuang

Adjunct Professor, Epidemiology
Professor, Psychiatry and Behavioral Sciences
Adjunct Professor, Medicine - Medical Genetics

206-277-1333

Education

MD University of Iowa, 1988

Contact

206-277-1333

Veterans Administration Puget Sound Health Care System
VAPSHCS (116-6E)
1660 S. Columbian Way
Mail Stop: GRECC-182
Seattle, WA 98108

Research Interests

  • Clinical-neuropathology of dementing disorders
  • Psychosis in dementia genetics
  • Endophenotypes of schizophrenia

Recent Publications (PubMed)

Medication-Wide Association Study of Alzheimer's Disease and Related Dementias: Identifying Drug Candidates from Electronic Health Records through Explainable AI.
(2026 Jun 3)
medRxiv
Shao Y, Yin Y, Cheng Y, McGeary JE, Taveira TH, Tsuang DW, Logue MW, Ayandeh S, Ahmed A, Zamrini E, Zeng-Treitler Q

A Genome-wide Association Study of Alzheimer's Disease and Dementia in a Large Multi-ancestry Military Cohort Identifies Many New Dementia-Associated Loci.
(2026 May 7)
medRxiv
Sherva R, Bayly H, Zhang R, Harrington K, Mez J, Miller MW, Tsuang D, Wolf E, Zeng Q, Le Guen Y, Tejeda M, VA Million Veteran Program, MVP Cognitive Decline and Dementia During Aging Working Group, Gaziano JM, Panizzon MS, Hauger RL, Merritt VC, Farrer LA, Logue MW

Can objective measures of physical activity and sleep serve as early predictors of dementia among individuals with cognitive impairment?
(2025 Dec 15)
medRxiv
Orr VL, Brown K, Wilson K, Dean P, Hu SC, Levendowski D, Seto E, Shutes-David A, Payne S, Cho Y, Tsuang DW

CSF α-Synuclein Seed Amplification Assays and Alzheimer Disease Biomarkers in Dementia With Lewy Bodies: Presentation and Progression.
(2025 Dec 23)
Neurology 105(12): e214346
Coughlin DG, Jain L, Khrestian M, Bozoki AC, Galvin JE, Irwin DJ, Lippa CF, Litvan I, Pillai JA, Tousi B, Lopez OL, Berman S, Tsuang DW, Zabetian CP, Fleisher JE, Taylor AS, Leverenz JB, Bekris LM, Galasko D, Dementia With Lewy Bodies Consortium

Machine learning-based risk scores are associated with conversion to dementia in Veterans.
(2025 Nov)
J Alzheimers Dis 108(2): 873-882
Brown K, Shutes-David A, Wilson K, Shao Y, Logue M, Zeng QT, Tsuang DW

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