Nona Sotoodehnia

Adjunct Professor, Epidemiology
Professor, Medicine - Cardiology
John Laughlin Endowed Professorship in Cardiovascular Research, Medicine - Cardiology



MPH Harvard School of Public Health, 1996
MD Harvard Medical School, 1996
BS Massachusetts Institute of Technology, 1991



Box 359748


Dr. Sotoodehnia, the John and Cookie Laughlin Endowed Professor in Cardiology, is co-director of the Cardiovascular Health Research Unit. She is a general cardiologist at Harborview Medical Center.

She conducts research on the genomics and epidemiology of cardiovascular diseases and risk factors. Her research focus includes cardiac arrhythmias and sudden cardiac arrest, diabetes and coronary heart disease. She and her group are leading efforts in precision medicine, examining drug-gene interactions, risk prediction and drug safety. Her work investigates gender and ethnic differences in cardiovascular risk and outcomes. In addition, she has a long interest in international health and is helping lead efforts in cardiovascular treatments in Nepal.

Research Interests

  • Preventive cardiology
  • Arrhythmias including sudden cardiac death and atrial fibrillation
  • Coronary heart disease
  • Precision medicine
  • International health
  • Diabetes and gender 
  • Ethnic differences in cardiovascular risk and outcomes

Recent Publications (PubMed)

Plasma proteins associated with plant-based diets: Results from the Atherosclerosis Risk in Communities (ARIC) study and Framingham Heart Study (FHS).
(2024 Jul 14)
Clin Nutr 43(8): 1929-1940
Kim H, Chen J, Prescott B, Walker ME, Grams ME, Yu B, Vasan RS, Floyd JS, Sotoodehnia N, Smith NL, Arking DE, Coresh J, Rebholz CM

Predicting Out-of-Hospital Cardiac Arrest in the General Population Using Electronic Health Records.
(2024 Jul 9)
Circulation 150(2): 102-110
Perry J, Brody JA, Fong C, Sunshine JE, O'Reilly-Shah VN, Sayre MR, Rea TD, Simon N, Shojaie A, Sotoodehnia N, Chatterjee NA

The Gut Microbial Metabolite Trimethylamine N -oxide, Incident CKD, and Kidney Function Decline.
(2024 Jun 1)
J Am Soc Nephrol 35(6): 749-760
Wang M, Tang WHW, Li XS, de Oliveira Otto MC, Lee Y, Lemaitre RN, Fretts A, Nemet I, Sotoodehnia N, Sitlani CM, Budoff M, DiDonato JA, Wang Z, Bansal N, Shlipak MG, Psaty BM, Siscovick DS, Sarnak MJ, Mozaffarian D, Hazen SL

Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations.
(2024 Dec)
Epigenetics 19(1): 2333668
Lundin JI, Peters U, Hu Y, Ammous F, Avery CL, Benjamin EJ, Bis JC, Brody JA, Carlson C, Cushman M, Gignoux C, Guo X, Haessler J, Haiman C, Joehanes R, Kasela S, Kenny E, Lapalainien T, Levy D, Liu C, Liu Y, Loos RJF, Lu A, Matise T, North KE, Park SL, Ratliff SM, Reiner A, Rich SS, Rotter JI, Smith JA, Sotoodehnia N, Tracy R, Van den Berg D, Xu H, Ye T, Zhao W, Raffield LM, Kooperberg C, PAGE Study

Ankle-Brachial Index and Risk of Sudden Cardiac Death in the Community: The ARIC Study.
(2024 Mar 19)
J Am Heart Assoc 13(6): e032008
Suzuki T, Zhu X, Adabag S, Matsushita K, Butler KR, Griswold ME, Alonso A, Rosamond W, Sotoodehnia N, Mosley TH

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