Faculty

Nona Sotoodehnia

Adjunct Professor, Epidemiology
Professor, Medicine - Cardiology
John Laughlin Endowed Professorship in Cardiovascular Research, Medicine - Cardiology

206-287-2777
nsotoo@uw.edu

Education

MPH Harvard School of Public Health, 1996
MD Harvard Medical School, 1996
BS Massachusetts Institute of Technology, 1991

Contact

206-287-2777
nsotoo@uw.edu

Box 359748
WA

Bio

Dr. Sotoodehnia, the John and Cookie Laughlin Endowed Professor in Cardiology, is co-director of the Cardiovascular Health Research Unit. She is a general cardiologist at Harborview Medical Center.

She conducts research on the genomics and epidemiology of cardiovascular diseases and risk factors. Her research focus includes cardiac arrhythmias and sudden cardiac arrest, diabetes and coronary heart disease. She and her group are leading efforts in precision medicine, examining drug-gene interactions, risk prediction and drug safety. Her work investigates gender and ethnic differences in cardiovascular risk and outcomes. In addition, she has a long interest in international health and is helping lead efforts in cardiovascular treatments in Nepal.

Research Interests

  • Preventive cardiology
  • Arrhythmias including sudden cardiac death and atrial fibrillation
  • Coronary heart disease
  • Precision medicine
  • International health
  • Diabetes and gender 
  • Ethnic differences in cardiovascular risk and outcomes

Recent Publications (PubMed)

Plasma Ceramides and Sphingomyelins and Sudden Cardiac Death in the Cardiovascular Health Study.
(2023 Nov 1)
JAMA Netw Open 6(11): e2343854
Bockus LB, Jensen PN, Fretts AM, Hoofnagle AN, McKnight B, Sitlani CM, Siscovick DS, King IB, Psaty BM, Sotoodehnia N, Lemaitre RN

Polygenic Risk Score Associates With Atherosclerotic Plaque Characteristics at Autopsy.
(2023 Nov 2)
Arterioscler Thromb Vasc Biol
Cornelissen A, Gadhoke NV, Ryan K, Hodonsky CJ, Mitchell R, Bihlmeyer N, Duong T, Chen Z, Dikongue A, Sakamoto A, Sato Y, Kawakami R, Mori M, Kawai K, Fernandez R, Ghosh SKB, Braumann R, Abebe B, Kutys R, Kutyna M, Romero ME, Kolodgie FD, Miller CL, Hong CC, Grove ML, Brody JA, Sotoodehnia N, Arking DE, Schunkert H, Mitchell BD, Guo L, Virmani R, Finn AV

Research opportunities for the primary prevention and management of acute rheumatic fever and rheumatic heart disease: a National Heart, Lung, and Blood Institute workshop report.
(2023 Oct)
BMJ Glob Health 8(Suppl 9):
Rwebembera J, Cannon JW, Sanyahumbi A, Sotoodehnia N, Taubert K, Yilgwan CS, Bukhman G, Masterson M, Bruno FP, Bowen A, Dale JB, Engel ME, Beaton A, Van Beneden C

Research priorities for the secondary prevention and management of acute rheumatic fever and rheumatic heart disease: a National Heart, Lung, and Blood Institute workshop report.
(2023 Oct)
BMJ Glob Health 8(Suppl 9):
Karthikeyan G, Watkins D, Bukhman G, Cunningham MW, Haller J, Masterson M, Mensah GA, Mocumbi A, Muhamed B, Okello E, Sotoodehnia N, Machipisa T, Ralph A, Wyber R, Beaton A

The functional impact of rare variation across the regulatory cascade.
(2023 Oct 11)
Cell Genom 3(10): 100401
Li T, Ferraro N, Strober BJ, Aguet F, Kasela S, Arvanitis M, Ni B, Wiel L, Hershberg E, Ardlie K, Arking DE, Beer RL, Brody J, Blackwell TW, Clish C, Gabriel S, Gerszten R, Guo X, Gupta N, Johnson WC, Lappalainen T, Lin HJ, Liu Y, Nickerson DA, Papanicolaou G, Pritchard JK, Qasba P, Shojaie A, Smith J, Sotoodehnia N, Taylor KD, Tracy RP, Van Den Berg D, Wheeler MT, Rich SS, Rotter JI, Battle A, Montgomery SB

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