Faculty

Alexander Reiner

Research Professor, Epidemiology

206-667-2710

Education

MD Internal Medicine, Johns Hopkins University, 1984
MSc Epidemiology, University of Washington, 2001

Contact

206-667-2710

Fred Hutch Cancer Center
Box 358080
WHI Clinical Coordinating Ctr / Public Health Sciences
M3-A4
Seattle, WA

Research Interests

Genetic epidemiology of atherosclerotic, thrombotic and cardiovascular disease; population biology; genomics

Recent Publications (PubMed)

Co-occurring clonal hematopoiesis exhibits strong selection and high leukemia risk.
(2026 May 21)
Nat Commun
Barnao KM, Hubbard AK, Chan ICC, Zhou W, Jakubek YA, Genovese G, Wong WSW, Kelly RL, Young CD, Brown DW, Huang WY, Freedman ND, Jones K, Hutchinson A, Hicks B, Tran D, Arnett D, Barnes KC, Bis JC, Boerwinkle E, Brody JA, Carson AP, Chasman DI, Cho MH, Desai P, Doyle MF, Fornage M, Guo X, Heard-Costa N, Irvin MR, Johnson AD, Kardia SLR, Kooperberg C, Levy D, Lewis JP, Li Y, Loos RJF, Mack TM, Mathias RA, Mitchell BD, North KE, Pankratz N, Peyser PA, Preuss MH, Psaty BM, Raffield LM, Redline S, Rich SS, Rotter JI, Silverman EK, Smith AV, Smith JA, Stilp A, Cao Y, Scheet P, Reiner AP, Bick AG, Chanock SJ, Auer PL, Bolton KL, Machiela MJ

Protein Biomarkers of Infertility Implicate Inflammation and Cell Growth/Remodeling Pathways.
(2026 May 8)
JACC Adv
Flores MN, Zhao Y, Li L, Spacht WA, Kooperberg C, Manson JE, Eaton CB, Reiner AP, Honigberg MC, Lau ES

An efficient LASSO framework for admixture-aware polygenic scores.
(2026 May 18)
HGG Adv 7(3): 100628
Ockerman F, Chen BD, Sun Q, Kharitonova EV, Chen C, Zhou LY, Loos RJF, Kooperberg C, Peters U, Haessler J, Reiner AP, Jung SY, Manson JE, Nassir R, North KE, Buyske S, Haiman CA, Conti DV, Wilkens LR, Lange EM, Cox NJ, Cao H, Raffield LM, Li Y, Tao R

Plasma proteomics link menopause timing to brain aging and dementia risk.
(2026 May 4)
Res Sq
Alexander MW, Wood B, See-Hwee Oh H, Bot VA, Borger J, Galbiati F, Walker KA, Resnick SM, Ochs-Balcom HM, Wyss-Coray T, Kooperberg C, Reiner AP, Jacobs EG, Rabin JS, Casaletto KB, Saloner R

Plasma metabolomic profiles associated with cardiovascular disease in type 2 diabetes from the Trans-Omics for Precision Medicine (TOPMed) program.
(2026 Apr 26)
Atherosclerosis 417(): 120758
Zhang Y, Nguyen NQH, Hanson PA, Sevilla-Gonzalez M, Haessler J, Sarnowski C, Yao J, Yu B, Jamshidi A, Boerwinkle E, Brown MR, Chen ZZ, Ida Chen YD, Clish C, DiCorpo D, Durda P, Gerszten R, Goodarzi MO, Guo X, Heard-Costa NL, Johnson WC, Kooperberg C, Pankow JS, Post WS, Reiner AP, Rich SS, Rotter JI, de Vries PS, Wood AC, Taylor KD, Manning AK, Dupuis J, Meigs JB, Liu CT

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