Faculty
Education
MD Internal Medicine, Johns Hopkins University, 1984
MSc Epidemiology, University of Washington, 2001
Contact
206-667-2710
apreiner@uw.edu
Fred Hutch Cancer Center
Box 358080
WHI Clinical Coordinating Ctr / Public Health Sciences
M3-A4
Seattle, WA
Box 358080
WHI Clinical Coordinating Ctr / Public Health Sciences
M3-A4
Seattle, WA
Research Areas
Research Interests
Genetic epidemiology of atherosclerotic, thrombotic and cardiovascular disease; population biology; genomics
Recent Publications (PubMed)
Clonal Hematopoiesis and Risk of Stroke: Evidence From Over 800 000 Individuals Across 3 Cohorts.
(2026 Apr 8)
Stroke
Zhao K, Pershad Y, Xue L, Vlasschaert C, Corty RW, Heimlich JB, Kooperberg C, Reiner AP, Bick AG
(2026 Apr 8)
Stroke
Zhao K, Pershad Y, Xue L, Vlasschaert C, Corty RW, Heimlich JB, Kooperberg C, Reiner AP, Bick AG
Multi-ancestry transcriptome prediction with functionally informed variants in TOPMed MESA improves performance of transcriptome-wide association studies.
(2026 Apr 2)
Am J Hum Genet 113(4): 828-841
Hu X, Araujo DS, Khunsriraksakul C, Wang L, Sun Q, Wen J, Zhou L, Ekunwe L, Lange LA, Lange EM, Montgomery SB, Reiner AP, Aguet F, Ardlie KG, Lappalainen T, Gignoux CR, Burchard EG, Taylor KD, Guo X, Rotter JI, Rich SS, Cornell E, Durda P, Tracy RP, Liu Y, Johnson WC, Papanicolaou GP, Perera MA, Cho MH, Liu DJ, Raffield LM, Li Y, TOPMed Multi-Omics Working Group, Wheeler HE, Im HK, Manichaikul A
(2026 Apr 2)
Am J Hum Genet 113(4): 828-841
Hu X, Araujo DS, Khunsriraksakul C, Wang L, Sun Q, Wen J, Zhou L, Ekunwe L, Lange LA, Lange EM, Montgomery SB, Reiner AP, Aguet F, Ardlie KG, Lappalainen T, Gignoux CR, Burchard EG, Taylor KD, Guo X, Rotter JI, Rich SS, Cornell E, Durda P, Tracy RP, Liu Y, Johnson WC, Papanicolaou GP, Perera MA, Cho MH, Liu DJ, Raffield LM, Li Y, TOPMed Multi-Omics Working Group, Wheeler HE, Im HK, Manichaikul A
Local ancestry modulates gene expression: shifting our understanding of genetic regulation and disease association within and across populations.
(2026 Mar 18)
medRxiv
Chen HH, Cai Y, Graff M, Zhu W, Petty LE, Highland HM, Roshani R, Polikowsky HG, Lorenz AS, Frankel E, Landman JM, Anwar MY, Franson EE, Haessler J, Avery CL, Young KL, Fernandez-Rhodes L, Reiner AP, Peters U, Gordon-Larsen P, Gamazon ER, Pereira AC, Kooperberg C, Huff CD, Fisher-Hoch SP, McCormick JB, North KE, Below JE
(2026 Mar 18)
medRxiv
Chen HH, Cai Y, Graff M, Zhu W, Petty LE, Highland HM, Roshani R, Polikowsky HG, Lorenz AS, Frankel E, Landman JM, Anwar MY, Franson EE, Haessler J, Avery CL, Young KL, Fernandez-Rhodes L, Reiner AP, Peters U, Gordon-Larsen P, Gamazon ER, Pereira AC, Kooperberg C, Huff CD, Fisher-Hoch SP, McCormick JB, North KE, Below JE
An integrated germline and somatic genomic model for coronary artery disease.
(2026 Mar 26)
Nat Commun
Yang X, Kim MS, Zhu X, Uddin MM, Nakao T, Cho SMJ, Koyama S, Xu T, Reeskamp LF, Zhang R, Liu Z, A Y, de Vries PS, Vasan RS, Boerwinkle E, Morrison AC, Psaty BM, Tracy RP, Heckbert SR, Cho MH, Yun JH, Palmer ND, Bowden DW, Murabito JM, Levy D, Heard-Costa NL, O'Connor GT, Becker LC, Kral BG, Yanek LR, Raffield LM, Hidalgo B, Rotter JI, Rich SS, Taylor KD, Post WS, Kooperberg C, Reiner AP, Mitchell BD, Kardia SLR, Smith JA, Peyser PA, Bielak LF, Yon DK, Won HH, Arnett DK, Smith AV, Gabriel SB, Ellinor PT, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Natarajan P, Wang M, Fahed AC
(2026 Mar 26)
Nat Commun
Yang X, Kim MS, Zhu X, Uddin MM, Nakao T, Cho SMJ, Koyama S, Xu T, Reeskamp LF, Zhang R, Liu Z, A Y, de Vries PS, Vasan RS, Boerwinkle E, Morrison AC, Psaty BM, Tracy RP, Heckbert SR, Cho MH, Yun JH, Palmer ND, Bowden DW, Murabito JM, Levy D, Heard-Costa NL, O'Connor GT, Becker LC, Kral BG, Yanek LR, Raffield LM, Hidalgo B, Rotter JI, Rich SS, Taylor KD, Post WS, Kooperberg C, Reiner AP, Mitchell BD, Kardia SLR, Smith JA, Peyser PA, Bielak LF, Yon DK, Won HH, Arnett DK, Smith AV, Gabriel SB, Ellinor PT, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Natarajan P, Wang M, Fahed AC
Plasma Proteins Associated With Psychosocial Factors and Heart Disease: The Jackson Heart Study.
(2026 May)
Arterioscler Thromb Vasc Biol 46(5): e324125
O'Brien SN, Gillman MG, Green MD, Cruz DE, Floyd JS, Hankinson S, Katz DH, Liu X, Odden MC, Psaty BM, Reiner AP, Rotter JI, Rich SS, Gerszten RE, Shah A, Sims M, Tahir UA, Tinker LF, Wood AC, Yu B, Zannas AS, Raffield LM, Glover LM
(2026 May)
Arterioscler Thromb Vasc Biol 46(5): e324125
O'Brien SN, Gillman MG, Green MD, Cruz DE, Floyd JS, Hankinson S, Katz DH, Liu X, Odden MC, Psaty BM, Reiner AP, Rotter JI, Rich SS, Gerszten RE, Shah A, Sims M, Tahir UA, Tinker LF, Wood AC, Yu B, Zannas AS, Raffield LM, Glover LM
Show complete publication list
In the News
SPH researchers take part in largest-ever genetic study of stroke
SPH News, 04/02/2018
SPH News, 04/02/2018
Study Links Sickle Cell Gene to Kidney Disease Risk
SPH News, 11/21/2014
SPH News, 11/21/2014
Sickle Cell Gene Linked to Chronic Kidney Disease
Journal of the American Medical Association, 11/13/2014
Journal of the American Medical Association, 11/13/2014
Discovery of 'broken gene' could advance heart disease research
My Northwest, 06/20/2014
My Northwest, 06/20/2014
Discovery of 'Broken Gene' Could Advance Heart Disease Research
MyNorthwest.com, 06/19/2014
MyNorthwest.com, 06/19/2014
Genetic Risk Factor Found for Inflammation in African-American Women
American Journal of Human Genetics, 09/07/2012
American Journal of Human Genetics, 09/07/2012
The cholesterol-inflammation connection
CNN.com, 10/20/2008
CNN.com, 10/20/2008