Epigenome-wide association study of nuclear DNA methylation in relation to mitochondrial heteroplasmy.
(2025 Dec 2)
Nat Commun
Lai M, Kim K, Zheng Y, Castellani CA, Ratliff SM, Wang M, Liu X, Haessler J, Huan T, Bonsu K, Newcomb C, McKessy K, Bielak LF, Zhao W, Joehanes R, Ma J, Guo X, Manson JE, Grove ML, Bressler J, Taylor KD, Lappalainen T, Kasela S, Blackwell TW, Lake NJ, Faul JD, Ferrier KR, Ekker SC, Hou L, Kooperberg C, Reiner AP, Zhang K, Peyser PA, Fornage M, Boerwinkle E, Raffield LM, Carson AP, Rich SS, Liu Y, Levy D, Rotter JI, Smith JA, Arking DE, Liu C, NHLBI Trans-Omics for Precision Medicine (TOPMed) mtDNA Working Group

Human plasma proteomic profile of clonal hematopoiesis.
(2025 Nov 27)
Nat Commun
Yu Z, Vromman A, Nguyen NQH, Schuermans A, Li L, Rentz T, Nakao T, Vellarikkal SK, Uddin MM, Niroula A, Griffin G, Honigberg MC, Lin AE, Gibson CJ, Katz DH, Tahir UA, Fang S, Dron JS, Pan M, Haidermota S, Ganesh S, Antoine T, Weinstock J, Austin TR, Vasan RS, Peloso GM, Hornsby W, Ganz P, Manson JE, Haring B, Kooperberg C, Reiner AP, Bis JC, Psaty BM, Min YI, Correa A, Lange LA, Post WS, Rotter JI, Rich SS, Wilson JG, Ebert BL, Yu B, Ballantyne CM, Coresh J, Sankaran VG, Bick AG, Jaiswal S, Gerszten RE, NHLBI Trans-Omics for Precision Medicine, Libby P, Gupta RM, Natarajan P

Plasma p-tau217 and incident mild cognitive impairment and dementia in older women: 25-year prospective study in The Women's Health Initiative Memory Study.
(2025 Nov 11)
medRxiv
Shadyab AH, Zhang B, LaCroix AZ, Mielke MM, Resnick SM, Nguyen S, Ferrucci L, Libermann TA, Ngo L, Casanova R, Reiner AP, Li D, Nievergelt CM, Maihofer AX, Manson JE, McEvoy LK

Association between neutrophil to lymphocyte ratio and Alzheimer's disease in large biobank cohorts.
(2025 Dec)
J Alzheimers Dis 108(3): 1302-1311
Drzymalla E, Avery C, Palta P, Reiner AP, Sun Q, Raffield LM

Clonal hematopoiesis of indeterminate potential and the risk of cognitive impairment in the Women's Health Initiative Memory Study.
(2025 Oct)
Alzheimers Dement 21(10): e70737
Jakubek YA, Smith AP, Leng XI, Hall ME, Ezzat D, Pershad Y, Collins JM, Uddin MM, Fardo DW, Natarajan P, Bick AG, Kitzman JO, Honigberg MC, Hayden KM, Manson JE, Jaiswal S, Whitsel EA, Reiner AP