Faculty

Alexander Reiner

Research Professor, Epidemiology

206-667-2710

Education

MD Internal Medicine, Johns Hopkins University, 1984
MSc Epidemiology, University of Washington, 2001

Contact

206-667-2710

Fred Hutch Cancer Center
Box 358080
WHI Clinical Coordinating Ctr / Public Health Sciences
M3-A4
Seattle, WA

Research Interests

Genetic epidemiology of atherosclerotic, thrombotic and cardiovascular disease; population biology; genomics

Recent Publications (PubMed)

Clonal hematopoiesis of indeterminate potential and the risk of cognitive impairment in the Women's Health Initiative Memory Study.
(2025 Oct)
Alzheimers Dement 21(10): e70737
Jakubek YA, Smith AP, Leng XI, Hall ME, Ezzat D, Pershad Y, Collins JM, Uddin MM, Fardo DW, Natarajan P, Bick AG, Kitzman JO, Honigberg MC, Hayden KM, Manson JE, Jaiswal S, Whitsel EA, Reiner AP

Association of genetic scores related to insulin resistance with neurological outcomes in ancestrally diverse cohorts from the Trans-Omics for Precision Medicine (TOPMed) program.
(2025 Sep 24)
Commun Biol 8(1): 1352
Sarnowski C, Zhang Y, Ammous F, Shade LMP, DiCorpo D, Jian X, Arnett DK, Austin TR, Beiser A, Bis JC, Blangero J, Boerwinkle E, Bressler J, Curran JE, DeCarli CS, Doddapaneni H, Dupuis J, Fardo DW, Florez JC, Gabriel S, Gibbs RA, Glahn DC, Gupta N, González HM, González KA, Hatzikotoulas K, Hayden KM, Heckbert SR, Hidalgo B, Huerta-Chagoya A, Hughes TM, Kardia SLR, Kooperberg CL, Launer LJ, Longstreth WT Jr, T2DGGI consortium, MAGIC consortium, Mandla R, Mathias RA, Morris AP, Mosley TH, Nasrallah IM, Nyquist P, Psaty BM, Qi Q, Raffield LM, Rayner NW, Reiner AP, Satizabal CL, Selvin E, Sevilla-Gonzalez MDR, Smith AV, Smith JA, Smith K, Snively BM, Southam L, Sofer T, Suzuki K, Taylor HJ, Udler MS, Viaud-Martinez KA, Wassertheil-Smoller S, Wood AC, Yanek LR, Yin X, Manning AK, Rotter JI, Rich SS, Meigs JB, Fornage M, Seshadri S, Morrison AC, TOPMed Diabetes working group, and the TOPMed Neurocognitive working group

Genetic architecture and analysis practices of circulating metabolites in the NHLBI Trans-Omics for Precision Medicine Program.
(2025 Sep 18)
Am J Hum Genet
Wang N, Ockerman FP, Zhou LY, Grove ML, Alkis T, Barnard J, Bowler RP, Clish CB, Chung S, Drzymalla E, Evans AM, Franceschini N, Gerszten RE, Gillman MG, Hutton SR, Kelly RS, Kooperberg C, Larson MG, Lasky-Su J, Meyers DA, Woodruff PG, Reiner AP, Rich SS, Rotter JI, Silverman EK, Vasan RS, Weiss ST, Wong KE, Wood AC, Wu L, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Yarden R, Blackwell TW, Smith AV, Chen H, Raffield LM, Yu B

An Efficient Lasso Framework for Admixture-Aware Polygenic Scores.
(2025 Aug 27)
bioRxiv
Ockerman F, Chen B, Sun Q, Kharitonova EV, Chen W, Zhou LY, Loos RJF, Kooperberg C, Peters U, Haessler J, Reiner A, Jung SY, Manson JE, Nassir R, North KE, Buyske S, Haiman CA, Conti DV, Wilkens LR, Lange EM, Cox NJ, Cao H, Raffield LM, Li Y, Tao R

Whole-genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia.
(2025 Aug 30)
HGG Adv 7(1): 100499
Li R, Gagliano Taliun SA, Liao K, Flickinger M, Sobell JL, Genovese G, Locke AE, Chiu RR, LeFaive J, Wang J, Martins T, Chapman S, Neumann A, Handsaker RE, Arnett DK, Barnes KC, Boerwinkle E, Braff D, Cade BE, Fornage M, Gibbs RA, Hoth KF, Hou L, Kooperberg C, Loos RJF, Metcalf GA, Montgomery CG, Morrison AC, Qin ZS, Redline S, Reiner AP, Rich SS, Rotter JI, Taylor KD, Viaud-Martinez KA, National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium, Genomic Psychiatry Cohort Investigators, Bigdeli TB, Gabriel S, Zollner S, Smith AV, Abecasis G, McCarroll SA, Pato MT, Pato CN, Boehnke M, Knowles J, Kang HM, Ophoff RA, Ernst J, Scott LJ

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