Faculty

Polly Newcomb

Research Professor, Epidemiology

206-667-3476
pnewcomb@fhcrc.org

Education

PhD Epidemiology, University of Washington, 1986
MPH Epidemiology, University of Washington, 1982

Contact

206-667-3476
pnewcomb@fhcrc.org

Fred Hutchinson Cancer Research Center
Box 358080 (M4-B402)
1100 Fairview Avenue N., M4-B402
Seattle, WA 98109

Research Areas

Research Interests

My interests are the identification of modifiable risk factors for common cancers--colorectal, breast, and endometrium. Increasingly, my work has focused on better characterizing individuals at risk because of the joint presentation of environmental and genetic factors. Over the past 20 years, I have conducted several large population based case-control studies of cancer etiology. Cases enrolled in these studies now form the basis for cohorts to examine factors associated with survivorship. I am also interested in the observational evaluations of screening efficacy.

Recent Publications (PubMed)

Does margin width impact breast cancer recurrence rates in women with breast conserving surgery for ductal carcinoma in situ?
(2021 Jun 15)
Breast Cancer Res Treat
Livingston-Rosanoff D, Trentham-Dietz A, Hampton JM, Newcomb PA, Wilke LG

Risk of Breast Cancer Among Carriers of Pathogenic Variants in Breast Cancer Predisposition Genes Varies by Polygenic Risk Score.
(2021 Jun 8)
J Clin Oncol
Gao C, Polley EC, Hart SN, Huang H, Hu C, Gnanaolivu R, Lilyquist J, Boddicker NJ, Na J, Ambrosone CB, Auer PL, Bernstein L, Burnside ES, Eliassen AH, Gaudet MM, Haiman C, Hunter DJ, Jacobs EJ, John EM, Lindström S, Ma H, Neuhausen SL, Newcomb PA, O'Brien KM, Olson JE, Ong IM, Patel AV, Palmer JR, Sandler DP, Tamimi R, Taylor JA, Teras LR, Trentham-Dietz A, Vachon CM, Weinberg CR, Yao S, Weitzel JN, Goldgar DE, Domchek SM, Nathanson KL, Couch FJ, Kraft P

Colorectal Cancer Anatomical Site and Sleep Quality.
(2021 May 25)
Cancers (Basel) 13(11):
Ton M, Watson NF, Sillah A, Malen RC, Labadie JD, Reedy AM, Cohen SA, Burnett-Hartman AN, Newcomb PA, Phipps AI

Nongenetic Determinants of Risk for Early-Onset Colorectal Cancer.
(2021 Jun)
JNCI Cancer Spectr 5(3): pkab029
Archambault AN, Lin Y, Jeon J, Harrison TA, Bishop DT, Brenner H, Casey G, Chan AT, Chang-Claude J, Figueiredo JC, Gallinger S, Gruber SB, Gunter MJ, Hoffmeister M, Jenkins MA, Keku TO, Marchand LL, Li L, Moreno V, Newcomb PA, Pai R, Parfrey PS, Rennert G, Sakoda LC, Sandler RS, Slattery ML, Song M, Win AK, Woods MO, Murphy N, Campbell PT, Su YR, Zeleniuch-Jacquotte A, Liang PS, Du M, Hsu L, Peters U, Hayes RB

Genetically Predicted Circulating C-Reactive Protein Concentration and Colorectal Cancer Survival: A Mendelian Randomization Consortium Study.
(2021 May 10)
Cancer Epidemiol Biomarkers Prev
Hua X, Dai JY, Lindström S, Harrison TA, Lin Y, Alberts SR, Alwers E, Berndt SI, Brenner H, Buchanan DD, Campbell PT, Casey G, Chang-Claude J, Gallinger S, Giles GG, Goldberg RM, Gunter MJ, Hoffmeister M, Jenkins MA, Joshi AD, Ma W, Milne RL, Murphy N, Pai RK, Sakoda LC, Schoen RE, Shi Q, Slattery ML, Song M, White E, Marchand LL, Chan AT, Peters U, Newcomb PA

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