Faculty

Lisa E. Manhart

Professor, Epidemiology
Adjunct Professor, Global Health


Education

PhD Epidemiology, University of Washington, 2002
MPH International Health & Development, Tulane University, 1994
BA French, Indiana University, 1982

Contact


Office 1313
Center for AIDS and STD
Harborview Medical Center, Box 359931
325 9th Avenue
Seattle, WA 98104
University of Washington
Office F-358C
Box 357236
Department of Epidemiology, School of Public Health
WA

Research Areas

Research Interests

Dr. Manhart’s research interests are in sexually transmitted infections (STI) and human immunodeficiency virus (HIV). Her primary research involves defining the clinical epidemiology of emerging STI pathogens, with a focus on Mycoplasma genitalium. She led the MEGA trial evaluating the efficacy of standard therapies against M. genitalium, and is currently leading two cohort studies of men with urethritis to explore the role of the male urethral microbiome in genital tract disease. Current projects also include studies of the psychosocial implications of STI and HIV-infection, including stigma and mental health, and studies to define the social context of STI risk.

Recent Publications (PubMed)

Sequential sex practices and the likelihood of bacterial sexually transmitted infections and urethritis in men who have sex with women.
(2026 Jun 23)
Sex Transm Dis
Waters MB, Chambers LC, Manhart LE, Romano SS, Wagner AD, Menza TW, Khosropour CM
Prevalence, Duration, and Severity of Rectal Symptoms Among Men Who Have Sex With Men With Rectal Sexually Transmitted Infections.
(2026 May)
Open Forum Infect Dis 13(5): ofag276
Zhang S, Barbee LA, Soge OO, Golden MR, Manhart LE, Khosropour CM
The Natural History of Mycoplasma genitalium in the Pharynx and Rectum in a Cohort of Men Who Have Sex With Men: Prevalence, Incidence, Duration, and Symptoms.
(2026 Jun 16)
J Infect Dis 233(6): 1091-1099
Barbee LA, Zhang S, Golden MR, Khosropour CM, Soge OO, Manhart LE
Dynamics of Gender Identity With STI Diagnoses and Behavioral Outcomes Among Seattle Sexual Health Clinic Attendees, 2016-2023.
(2026 Mar 1)
Sex Transm Dis 53(3): 141-146
Lang JC, Cannon CA, Manhart LE, Berzkalns A, Kerani RP
Study Design Matters: Using a Rigorous Analytic Design to Examine the Association Between Rectal Douching and Incident Rectal Gonorrhea and Chlamydia.
(2026 Jan 1)
Sex Transm Dis 53(1): 36-41
Chrzanowski E, Barbee LA, Manhart LE, Khosropour CM
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