Faculty

Kathleen E Malone

Research Professor, Epidemiology

206-667-4632

Education

PhD Epidemiology, University of Washington, 1993
MPH Epidemiology, Yale University, 1984
BSW Social Work, Temple University, 1978

Contact

206-667-4632

Fred Hutch Cancer Center
Box 358080 M4-C308
Division of Public Health Sciences
1100 Fairview Ave N, Arnold Building
PO Box 19024, Mailstop: M4-C308
Seattle, WA 98109

Bio

Dr. Malone is also the Head of the Program in Epidemiology at the Fred Hutchinson Cancer Research Center in Seattle, Washington.

Research Areas

Research Interests

My research focuses on breast cancer and involves three emphasis areas: etiology, genetics, and outcomes after breast cancer. Cancer survivorship has become a major focus and in this regard, I have conducted several population-based studies of the personal, lifestyle, medical, and tumor-based determinants of breast cancer recurrence and mortality. I have also led/co-led studies of second primary breast cancer in relation to treatment for the first primary, germline genetics and mammographic density. Currently, I am leading a new study of the molecular features of first and second primary breast cancers with dual foci on second primary risk prediction and the concordance of molecular features in paired tumors. We also have a current study examining risk factors for the four most common second primary cancers after breast cancer. Collectively, this research aims to develop tools for identifying those at high risk of adverse outcomes after breast cancer and to identify potential preventive strategies.

Recent Publications (PubMed)

Breast Cancer Susceptibility Gene Sequence Variations and Development of Contralateral Breast Cancer.
(2024 Dec 2)
JAMA Netw Open 7(12): e2452158
Reiner AS, Watt GP, Malone KE, Lynch CF, John EM, Knight JA, Woods M, Liang X, Tischkowitz M, Conti DV, Robson ME, Mellemkjær L, Teraoka SN, Concannon P, Bernstein JL
Statin use after cancer diagnosis and survival among patients with cancer.
(2025 Apr)
Cancer Causes Control 36(4): 443-455
Guo H, Malone KE, Heckbert SR, Li CI
Metabolic Syndrome and Risks of Breast Cancer Outcomes for Luminal, Triple-Negative, and HER2-Overexpressing Subtypes.
(2025 Jan 9)
Cancer Epidemiol Biomarkers Prev 34(1): 117-124
Loroña NC, Othus M, Malone KE, Linden HM, Tang MC, Li CI
Reply to "Critical analysis of the study from Reiner et al. on agreement of medical record abstraction and self-report of breast cancer treatment".
(2024 Dec 1)
Cancer 130(23): 4151-4152
Reiner AS, Knight JA, John EM, Lynch CF, Malone KE, Liang X, Woods M, Root JC, Bernstein JL
Agreement of medical record abstraction and self-report of breast cancer treatment with an extended recall window.
(2025 Jan 1)
Cancer 131(1): e35459
Reiner AS, Knight JA, John EM, Lynch CF, Malone KE, Liang X, Woods M, Root JC, Bernstein JL
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