Kathleen E Malone

Research Professor, Epidemiology



PhD Epidemiology, University of Washington, 1993
MPH Epidemiology, Yale University, 1984
BSW Social Work, Temple University, 1978



Fred Hutchinson Cancer Research Center
Box 358080 M4-C308
Division of Public Health Sciences
1100 Fairview Ave N, Arnold Building
PO Box 19024, Mailstop: M4-C308
Seattle, WA 98109


Dr. Malone is also the Head of the Program in Epidemiology at the Fred Hutchinson Cancer Research Center in Seattle, Washington.

Research Areas

Research Interests

My research focuses on breast cancer and involves three emphasis areas: etiology, genetics, and outcomes after breast cancer. Cancer survivorship has become a major focus and in this regard, I have conducted several population-based studies of the personal, lifestyle, medical, and tumor-based determinants of breast cancer recurrence and mortality. I have also led/co-led studies of second primary breast cancer in relation to treatment for the first primary, germline genetics and mammographic density. Currently, I am leading a new study of the molecular features of first and second primary breast cancers with dual foci on second primary risk prediction and the concordance of molecular features in paired tumors. We also have a current study examining risk factors for the four most common second primary cancers after breast cancer. Collectively, this research aims to develop tools for identifying those at high risk of adverse outcomes after breast cancer and to identify potential preventive strategies.

Recent Publications (PubMed)

Trends in Radiation Dose to the Contralateral Breast During Breast Cancer Radiation Therapy.
(2023 Aug 16)
Radiat Res
Watt GP, Smith SA, Howell RM, Pérez-Andújar A, Reiner AS, Cerviño L, McCormick B, Hess D, Knight JA, Malone KE, John EM, Bernstein L, Lynch CF, Mellemkjær L, Shore RE, Liang X, Woods M, Boice JD, Dauer LT, Bernstein JL

Alcohol consumption, smoking, and invasive breast cancer risk after ductal carcinoma in situ.
(2022 Jun)
Breast Cancer Res Treat 193(2): 477-484
Jordahl KM, Malone KE, Baglia ML, Flanagan MR, Tang MC, Porter PL, Li CI

Association of contralateral breast cancer risk with mammographic density defined at higher-than-conventional intensity thresholds.
(2022 Oct 15)
Int J Cancer 151(8): 1304-1309
Watt GP, Knight JA, Nguyen TL, Reiner AS, Malone KE, John EM, Lynch CF, Brooks JD, Woods M, Liang X, Bernstein L, Pike MC, Hopper JL, Bernstein JL

Association between antidepressant use and second breast cancer event after ductal carcinoma in situ diagnosis: a nested case-control study.
(2022 Apr)
Cancer Causes Control 33(4): 593-600
Mansi ET, Malone KE, Tang MT, Loroña NC, Li CI

Mammographic texture features associated with contralateral breast cancer in the WECARE Study.
(2021 Nov 29)
NPJ Breast Cancer 7(1): 146
Watt GP, Knight JA, Lin C, Lynch CF, Malone KE, John EM, Bernstein L, Brooks JD, Reiner AS, Liang X, Woods M, Nguyen TL, Hopper JL, Pike MC, Bernstein JL

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