Faculty

Sara Lindstroem

Associate Professor, Epidemiology

206-221-3148

Education

MSc Engineering Physics, Umea University, 2004
PhD Genetic Epidemiology, Umea University, 2007

Contact

206-221-3148

University of Washington
Box 351619
Department of Epidemiology
Hans Rosling Center for Population Health, 874A
Seattle, WA 98195
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Bio

Pronouns: she/her/hers

Dr. Lindstroem (Lindstrom/Lindström) is a genetic epidemiologist who seeks to understand the genetic contribution to complex disease with an emphasis on cancer. She works at the intersection of statistical genetics and genetic epidemiology, where she always seeks to apply novel statistical methods on large-scale -omics data. By leveraging large-scale population-based studies, she studies how our genes and environment affect our risk of developing disease. She leads multiple international efforts to study genetic risk factors for cancer and mammographic density (R01CA194393, R01CA244670), and she is studying the genetics underlying a range of outcomes in people living with HIV (R01DA047045). Dr. Lindstroem also teaches PHG511 “Genetic Epidemiology”, EPI583 “Epidemiology Seminars”, and co-teaches the “Genetic Epidemiology” module as part of the UW Summer Institute of Statistical Genetics (SISG).

Research Interests

My research focuses on understanding the genetic contribution to common complex diseases, with a primary emphasis on cancer and linked traits. By leveraging long-running large population-based studies, I investigate how our genetics and environment affect our risk of developing disease.

Current research projects include studying the shared genetic origin between common cancers and the genetics underlying childhood obesity, breast tissue composition and venous thromboembolism. I am also interested in finding approaches to incorporate information about the functional characteristics of the genome in my studies. Finally, I am involved in several large-scale international collaborations that study the genetics underlying breast and prostate cancer.

Recent Publications (PubMed)

NON-ADDITIVE EFFECTS OF COMMON GENETIC VARIANTS HAVE A NEGLIGENT CONTRIBUTION TO CANCER HERITABILITY.
(2024 Jul 17)
Cancer Epidemiol Biomarkers Prev
Hammermeister Suger A, Harrison TA, Henning B, Turman C, Kraft P, Lindström S

Last general practitioner consultation during the final month of life: a national medical record review of suicides in Sweden.
(2024 Jul 15)
BMC Prim Care 25(1): 256
Öberg NP, Lindström SP, Bergqvist E, Ehnvall A, Sellin T, Stefenson A, Sunnqvist C, Waern M, Westrin Å

Disentangling the relationships of body mass index and circulating sex hormone concentrations in mammographic density using Mendelian randomization.
(2024 Jul)
Breast Cancer Res Treat 206(2): 295-305
Haas CB, Chen H, Harrison T, Fan S, Gago-Dominguez M, Castelao JE, Bolla MK, Wang Q, Dennis J, Michailidou K, Dunning AM, Easton DF, Antoniou AC, Hall P, Czene K, Andrulis IL, Mulligan AM, Milne RL, Fasching PA, Haeberle L, Garcia-Closas M, Ahearn T, Gierach GL, Haiman C, Maskarinec G, Couch FJ, Olson JE, John EM, Chenevix-Trench G, Berrington de Gonzalez A, Jones M, Stone J, Murphy R, Aronson KJ, Wernli KJ, Hsu L, Vachon C, Tamimi RM, Lindström S

Genetic Risk, Health-Associated Lifestyle, and Risk of Early-onset Total Cancer and Breast Cancer.
(2024 Apr 6)
medRxiv
Zhang Y, Lindström S, Kraft P, Liu Y

Identifying patterns of reported findings on long-term cardiac complications of COVID-19: a systematic review and meta-analysis.
(2023 Nov 28)
BMC Med 21(1): 468
Guo B, Zhao C, He MZ, Senter C, Zhou Z, Peng J, Li S, Fitzpatrick AL, Lindström S, Stebbins RC, Noppert GA, Li C

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