Faculty

Christopher I-Fu Li

Research Professor, Epidemiology

206-667-7444

Education

MD Medicine, University of California (San Francisco), 2000
PhD Epidemiology, University of Washington, 2003
MPH Epidemiology, University of Washington, 2000

Contact

206-667-7444

Fred Hutchinson Cancer Research Center
Box 358080
1100 Fairview Ave N., M4-C308
P.O. 19024
Seattle, WA 98109
View Website »

Research Interests

Dr. Li is a cancer epidemiologist based at the Fred Hutchinson Cancer Research Center with research projects spanning cancer early detection/screening, etiology, and survivorship. He has significant expertise in cancer epidemiology and substantial experience in the design, leadership, and completion of multidisciplinary studies of cancer. Current research projects include: 1. A large population-based study of different molecular subtypes of breast cancer aimed at elucidating their risk factors and identifying novel subtype-specific tumor markers useful for predicting risk of disease recurrence (DOD Collaborative Innovator Award); 2. A nested case-control study of women with DCIS who did and did not go on to develop a second breast cancer aimed at developing novel epidemiologic, clinical, and molecular approaches for guiding clinical decision making for DCIS patients (R01); 3. Discovering and validating novel blood-based markers useful for the early detection of breast, colorectal, and ovarian cancers (U01); 4. Characterizing risk factors for second primary breast, lung, colorectal, and endometrial cancers among breast cancer survivors (R01); and 5. Discovering and validating novel biomarkers useful for assessing risk of recurrence among colorectal cancer survivors (R01 and U01). Selected leaderships activities include: 1. Serving as the co-PI of the Cancer Surveillance System (CSS), the Seattle-Puget Sound Surveillance, Epidemiology and End Results (SEER) cancer registry, 2. Chairing the DOD Breast Cancer Research Program’s Integration Panel (FY 2017), and 3. Co-chairing the 2017 AACR Conference on the Science of Cancer Health Disparities.

Recent Publications (PubMed)

Incidence Rate Trends of Breast Cancer Overall and by Molecular Subtype by Race and Ethnicity and Age.
(2025 Jan 2)
JAMA Netw Open 8(1): e2456142
Li NHY, Li CI

Refining breast cancer genetic risk and biology through multi-ancestry fine-mapping analyses of 192 risk regions.
(2025 Jan)
Nat Genet 57(1): 80-87
Jia G, Chen Z, Ping J, Cai Q, Tao R, Li C, Bauer JA, Xie Y, Ambs S, Barnard ME, Chen Y, Choi JY, Gao YT, Garcia-Closas M, Gu J, Hu JJ, Iwasaki M, John EM, Kweon SS, Li CI, Matsuda K, Matsuo K, Nathanson KL, Nemesure B, Olopade OI, Pal T, Park SK, Park B, Press MF, Sanderson M, Sandler DP, Shen CY, Troester MA, Yao S, Zheng Y, Ahearn T, Brewster AM, Falusi A, Hennis AJM, Ito H, Kubo M, Lee ES, Makumbi T, Ndom P, Noh DY, O'Brien KM, Ojengbede O, Olshan AF, Park MH, Reid S, Yamaji T, Zirpoli G, Butler EN, Huang M, Low SK, Obafunwa J, Weinberg CR, Zhang H, Zhao H, Cote ML, Ambrosone CB, Huo D, Li B, Kang D, Palmer JR, Shu XO, Haiman CA, Guo X, Long J, Zheng W

Statin use after cancer diagnosis and survival among patients with cancer.
(2024 Dec 25)
Cancer Causes Control
Guo H, Malone KE, Heckbert SR, Li CI

ROSIE: AI generation of multiplex immunofluorescence staining from histopathology images.
(2024 Nov 18)
bioRxiv
Wu E, Bieniosek M, Wu Z, Thakkar N, Charville GW, Makky A, Schürch C, Huyghe JR, Peters U, Li CI, Li L, Giba H, Behera V, Raman A, Trevino AE, Mayer AT, Zou J

Associations Between Dietary Patterns and Quality of Life in a Longitudinal Cohort of Colorectal Cancer Survivors.
(2024 Nov 12)
Nutrients 16(22):
Smith KS, Gudenkauf LM, Hoogland AI, Li X, Hoobler R, Playdon MC, Gigic B, Small BJ, Gonzalez BD, Oswald LB, Byrd DA, Greathouse KL, Ulrich CM, Li CI, Shibata D, Toriola AT, Peoples AR, Siegel EM, Figueiredo JC, Jim HSL, Crowder SL

Show complete publication list