Faculty

Christopher I-Fu Li

Research Professor, Epidemiology

206-667-7444

Education

MD Medicine, University of California (San Francisco), 2000
PhD Epidemiology, University of Washington, 2003
MPH Epidemiology, University of Washington, 2000

Contact

206-667-7444

Fred Hutch Cancer Center
Box 358080
1100 Fairview Ave N., M4-C308
P.O. 19024
Seattle, WA 98109
View Website »

Research Interests

Dr. Li is a cancer epidemiologist based at the Fred Hutchinson Cancer Research Center with research projects spanning cancer early detection/screening, etiology, and survivorship. He has significant expertise in cancer epidemiology and substantial experience in the design, leadership, and completion of multidisciplinary studies of cancer. Current research projects include: 1. A large population-based study of different molecular subtypes of breast cancer aimed at elucidating their risk factors and identifying novel subtype-specific tumor markers useful for predicting risk of disease recurrence (DOD Collaborative Innovator Award); 2. A nested case-control study of women with DCIS who did and did not go on to develop a second breast cancer aimed at developing novel epidemiologic, clinical, and molecular approaches for guiding clinical decision making for DCIS patients (R01); 3. Discovering and validating novel blood-based markers useful for the early detection of breast, colorectal, and ovarian cancers (U01); 4. Characterizing risk factors for second primary breast, lung, colorectal, and endometrial cancers among breast cancer survivors (R01); and 5. Discovering and validating novel biomarkers useful for assessing risk of recurrence among colorectal cancer survivors (R01 and U01). Selected leaderships activities include: 1. Serving as the co-PI of the Cancer Surveillance System (CSS), the Seattle-Puget Sound Surveillance, Epidemiology and End Results (SEER) cancer registry, 2. Chairing the DOD Breast Cancer Research Program’s Integration Panel (FY 2017), and 3. Co-chairing the 2017 AACR Conference on the Science of Cancer Health Disparities.

Recent Publications (PubMed)

Investigating the relationship of plasma microRNAs and colorectal cancer risk using genetic evidence.
(2025 Oct 2)
BMC Med 23(1): 532
Bouras E, Papagiannopoulos CK, Mustafa R, Sobieski D, Schmit SL, Wu AH, Brenner H, Li CI, Chan AT, Pellatt AJ, Zheng W, Keku TO, Moreno V, Um CY, Van Guelpen B, Phipps AI, Pai RK, Lewis SJ, Martin RM, Gunter MJ, Peters U, Dehghan A, Tsilidis KK

Obesity promotes conserved inflammatory and metabolic transcriptional programs in colon tumors: Evidence from mouse models and the ColoCare Study patient cohort.
(2025 Sep 23)
Am J Clin Nutr
Glenny EM, Lin T, Bandera VM, Mirminachi B, Khumukcham SS, Gigic B, Warby CA, Aksonova O, Coleman MF, Carpanese A, Busch C, Himbert C, Ose J, Nix DA, Boucher K, Schirmacher P, Strehli I, Hardikar S, Cohan JN, Jedrzkiewicz J, Brobeil A, Schneider MA, Kahlert C, Siegel EM, Byrd DA, Toriola AT, Shibata D, Li CI, Figueiredo JC, Tan AC, Roper J, Ulrich CM, Hursting SD

Associations of Biomarkers of Systemic Inflammation, Angiogenesis, and Cell-to-Cell Adhesion With Tumor Budding Among Early-Onset and Later-Onset Colorectal Cancer Patients.
(2025 Sep)
Cancer Med 14(18): e71267
Hausmann O, Schobert PP, Ose J, Himbert C, Pletneva M, Jedrzkiewicz J, Nguyen A, Lin T, Warby CA, Hardikar S, Peoples AR, Strehli I, Huang LC, Cohan JN, Pickron B, Scaife C, Li CI, Grady WM, Shibata D, Toriola AT, Schneider M, Figueiredo JC, Siegel EM, Gigic B, Herzig S, Ilozumba MN, Ulrich CM

Gaps in care across the cancer screening continuum for cervical, colorectal and lung cancer.
(2025 Sep 10)
J Natl Cancer Inst
Haas JS, Todd KW, Mclerran D, Tiro JA, Vachani A, Kobrin S, Saia C, Sugg Skinner C, Zheng Y, Chubak J, Corley DA, Greenlee RT, Halm EA, Li CI

Pre-surgery gut microbial diversity and abundance are associated with post-surgery onset of cachexia in colorectal cancer patients: the ColoCare Study.
(2025 Sep 4)
Cancer Causes Control
Ilozumba MN, Gomez MF, Lin T, Himbert C, Round JL, Zac Stephens W, Warby CA, Hardikar S, Li CI, Figueiredo JC, Damerell V, Fillmore GC, Pickron B, Toriola AT, Shibata D, Holowatyj AN, Kahlert C, Sankar K, Siegel EM, Jedrzkiewicz J, Gigic B, Byrd DA, Ose J, Ulrich CM

Show complete publication list