Faculty

Sylvia Lacourse

Adjunct Assistant Professor, Epidemiology
Assistant Professor, Medicine - Allergy and Infectious Dis.
Assistant Professor, Global Health

206-616-5978
sylvial2@uw.edu

Education

MD University of Louisville, 2007
BA Environmental Science, University of California (Santa Barbara), 1995

Contact

206-616-5978
sylvial2@uw.edu

Box 359931
325 9th Avenue
Seattle, WA 98104

Bio

Dr. LaCourse’s research focuses on improved tuberculosis prevention, screening, and detection with a focus on people with HIV, including pregnant people and children. She leads clinical cohorts of pregnant people and children evaluating diagnostics for latent and active TB infection as well as interventional studies evaluating TB prevention therapy including among HIV-exposed uninfected children and pregnant people with HIV. Active areas of research include evaluation of non-sputum based TB diagnostics as well as the role of pregnancy and HIV in TB susceptibility. An additional area of scientific focus is SAR-CoV-2 antibody responses in pregnant people and their infants.

Dr. LaCourse is a GWACh (Global Women, Adolescent, and Child health) scientific lead, Kenya Research and Training Center (KRTC) faculty member, Tuberculosis Research & Training Center (TRTC) leadership committee member, and TB ECHO (Extension for Community Healthcare Outcomes) faculty, and co-leads the Development core of the recently awarded NIH Seattle TB Research Advancement Center (SEA-TRAC). She is committed to the inclusion of children and pregnant women in HIV/TB research as an IMPAACT (International Maternal Pediatric Adolescent AIDS Clinical Trials Network) TB Scientific Committee mentored junior investigator, and International Union Against TB and Lung Disease Maternal Child Health Working Group Scientific Co-Lead.

She is an attending physician at the Madison HIV clinic and infectious diseases, general medicine, and HIV inpatient services at the University of Washington and Harborview Medical Centers.

Recent Publications (PubMed)

Tuberculosis preventative therapy initiation and completion among adolescents and young adults with HIV in Kenya.
(2023 Jan 31)
J Acquir Immune Defic Syndr
Black DA, LaCourse SM, Njuguna IN, Beima-Sofie KM, Mburu CW, Mugo C, Itindi JAY, Onyango AD, Richardson BA, Wamalwa DC, John-Stewart GC

Tuberculosis Infection in Pregnant People: Current Practices and Research Priorities.
(2022 Dec 6)
Pathogens 11(12):
Mathad JS, Yadav S, Vaidyanathan A, Gupta A, LaCourse SM

Development of a Clinical Prediction Score Including Monocyte-to-Lymphocyte Ratio to Inform Tuberculosis Treatment Among Children With HIV: A Multicountry Study.
(2022 Nov)
Open Forum Infect Dis 9(11): ofac548
Malik AA, Gandhi NR, Marcy O, Walters E, Tejiokem M, Chau GD, Omer SB, Lash TL, Becerra MC, Njuguna IN, LaCourse SM, Maleche-Obimbo E, Wamalwa D, John-Stewart GC, Cranmer LM

Adverse pregnancy outcomes after in vitro fertilization due to undiagnosed urogenital tuberculosis and proposed screening algorithm for patients from tuberculosis-endemic countries.
(2022 Sep)
F S Rep 3(3): 285-291
McLaughlin SE, Vora SB, Church EC, Spitters C, Thyer A, LaCourse S, Herndon CN

Brief Report: Performance of Tuberculosis Symptom Screening Among Hospitalized ART-Naive Children With HIV in Kenya.
(2022 Nov 1)
J Acquir Immune Defic Syndr 91(3): 280-284
Cranmer LM, Njuguna IN, LaCourse SM, Figueroa J, Gillespie S, Maleche-Obimbo E, Otieno V, Mugo C, Okinyi H, Benki-Nugent S, Pavlinac PB, Malik AA, Gandhi NR, Richardson BA, Stern J, Wamalwa DC, John-Stewart GC

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