Faculty

Sylvia M LaCourse

Adjunct Associate Professor, Epidemiology
Associate Professor, Medicine - Allergy and Infectious Dis.
Associate Professor, Global Health
Robert W. Anderson Endowed Chair in Medicine, Medicine - Allergy and Infectious Dis.

206-616-5978

Education

MD University of Louisville, 2007
BA Environmental Science, University of California (Santa Barbara), 1995

Contact

206-616-5978

Box 359931
325 9th Avenue
Seattle, WA 98104

Bio

Dr. LaCourse’s research focuses on improved tuberculosis prevention, screening, and detection with a focus on people with HIV, including pregnant people and children. She leads clinical cohorts of pregnant people and children evaluating diagnostics for latent and active TB infection as well as interventional studies evaluating TB prevention therapy including among HIV-exposed uninfected children and pregnant people with HIV. Active areas of research include evaluation of non-sputum based TB diagnostics as well as the role of pregnancy and HIV in TB susceptibility. An additional area of scientific focus is SAR-CoV-2 antibody responses in pregnant people and their infants.

Dr. LaCourse is a GWACh (Global Women, Adolescent, and Child health) scientific lead, Kenya Research and Training Center (KRTC) faculty member, Tuberculosis Research & Training Center (TRTC) leadership committee member, and TB ECHO (Extension for Community Healthcare Outcomes) faculty, and co-leads the Development core of the recently awarded NIH Seattle TB Research Advancement Center (SEA-TRAC). She is committed to the inclusion of children and pregnant women in HIV/TB research as an IMPAACT (International Maternal Pediatric Adolescent AIDS Clinical Trials Network) TB Scientific Committee mentored junior investigator, and International Union Against TB and Lung Disease Maternal Child Health Working Group Scientific Co-Lead.

She is an attending physician at the Madison HIV clinic and infectious diseases, general medicine, and HIV inpatient services at the University of Washington and Harborview Medical Centers.

Recent Publications (PubMed)

Hybrid immunity to SARS-CoV-2 during pregnancy provides more durable infant antibody responses compared to natural infection or vaccination alone.
(2024 Jan 29)
J Infect Dis
LaCourse SM, Wetzler EA, Aurelio MC, Escudero JN, Selke SS, Greninger AL, Goecker EA, Barnes SR, Arnould IS, Pérez-Osorio AC, Richardson BA, Kachikis A, Englund JA, Drake AL

Hybrid immunity to SARS-CoV-2 during pregnancy provides more durable infant antibody responses compared to natural infection alone.
(2023 Dec 21)
J Infect Dis
LaCourse SM, Wetzler EA, Aurelio MC, Escudero JN, Selke SS, Greninger AL, Goecker EA, Barnes SR, Arnould IS, Pérez-Osorio AC, Richardson BA, Kachikis A, Englund JA, Drake AL

Notes from the Field: Undiagnosed Tuberculosis During Pregnancy Resulting in a Neonatal Death - United States, 2021.
(2023 Dec 8)
MMWR Morb Mortal Wkly Rep 72(49): 1331-1332
Miele K, Rock RB, LaCourse SM, Ashkin D, Armitige LY, Pomputius W, Goswami ND

Effect of TB-HIV co-treatment on clinical and growth outcomes among hospitalized children newly initiating antiretroviral therapy.
(2023 Nov 28)
AIDS
Cherkos AS, Cranmer LM, Njuguna I, LaCourse SM, Mugo C, Moraa H, Maleche-Obimbo E, Enquobahrie DA, Richardson BA, Wamalwa D, John-Stewart G

Maternal HIV Status and Risk of Infant Mycobacterium Tuberculosis Infection as Measured by Tuberculin Skin Test.
(2023 Nov 22)
Pediatr Infect Dis J
Mecha J, Escudero JN, Richardson BA, Maleche-Obimbo E, Matemo D, Kinuthia J, John-Stewart G, LaCourse SM

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