Faculty

Walter A Kukull

Professor, Epidemiology

206-543-4560

Education

PhD Epidemiology, University of Washington, 1983
MS Psychology, Western Washington University, 1974

Contact

206-543-4560

Box 357236
Dept. of Epidemiology
1959 NE Pacific Street
Health Sciences, F-261G
Seattle, WA 98195
National Alzheimer's Coordinating Center
Box 354983
4311 11th Avenue NE #300
Seattle, WA 98105
View Website »

Research Interests

Dr Kukull's research is principally in the neurodegenerative, vascular and other conditions causing dementia and cognitive impairment. These conditions include Alzheimer's disease, Parkinson's/Lewy body disease, frontotemporal lobar degeneration, and cerebrovascular disease. Since 1999, as Director and PI of the National Alzheimer's Coordinating Center [U01AG016976], he is closely tied to the ~30 Alzheimer's Disease Centers nationwide, funded by National Institute on Aging. In addition to NACC work, he is an investigator with a number of other NIH grants.

Recent Publications (PubMed)

Evaluating the association of APOE genotype and cognitive resilience in SuperAgers.
(2025 Jan 7)
medRxiv
Durant A, Mukherjee S, Lee ML, Choi SE, Scollard P, Klinedinst BS, Trittschuh EH, Mez J, Farrer LA, Gifford KA, Cruchaga C, Hassenstab J, Naj AC, Wang LS, Johnson SC, Engelman CD, Kukull WA, Keene CD, Saykin AJ, Cuccaro ML, Kunkle BW, Pericak-Vance MA, Martin ER, Bennett DA, Barnes LL, Schneider JA, Bush WS, Haines JL, Mayeux R, Vardarajan BN, Albert MS, Thompson PM, Jefferson AL, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Alzheimer’s Disease Genetics Consortium (ADGC), The Alzheimer’s Disease Sequencing Project (ADSP), Crane PK, Dumitrescu L, Archer DB, Hohman TJ, Gaynor LS

Lewy body co-pathology in Alzheimer's disease and primary age-related tauopathy contributes to differential neuropathological, cognitive, and brain atrophy patterns.
(2025 Jan)
Alzheimers Dement 21(1): e14191
Almeida FC, Santos A, Jesus T, Coelho A, Quintas-Neves M, Gauthreaux K, Mock CN, Kukull WA, Crary JF, Oliveira TG

Sex and APOE ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease.
(2025 Jan)
Alzheimers Dement 21(1): e14343
Peterson A, Sathe A, Zaras D, Yang Y, Durant A, Deters KD, Shashikumar N, Pechman KR, Kim ME, Gao C, Mohd Khairi N, Li Z, Yao T, Huo Y, Dumitrescu L, Gifford KA, Wilson JE, Cambronero FE, Risacher SL, Beason-Held LL, An Y, Arfanakis K, Erus G, Davatzikos C, Tosun D, Toga AW, Thompson PM, Mormino EC, Habes M, Wang D, Zhang P, Schilling K, Alzheimer's Disease Neuroimaging Initiative (ADNI), BIOCARD Study Team, Alzheimer's Disease Sequencing Project (ADSP), Albert M, Kukull W, Biber SA, Landman BA, Johnson SC, Schneider J, Barnes LL, Bennett DA, Jefferson AL, Resnick SM, Saykin AJ, Hohman TJ, Archer DB

X-chromosome-wide association study for Alzheimer's disease.
(2024 Dec 4)
Mol Psychiatry
Le Borgne J, Gomez L, Heikkinen S, Amin N, Ahmad S, Choi SH, Bis J, Grenier-Boley B, Rodriguez OG, Kleineidam L, Young J, Tripathi KP, Wang L, Varma A, Campos-Martin R, van der Lee S, Damotte V, de Rojas I, Palmal S, EADB, GR@ACE, DEGESCO, EADI, GERAD, DemGene, FinnGen, ADGC, CHARGE, Lipton R, Reiman E, McKee A, De Jager P, Bush W, Small S, Levey A, Saykin A, Foroud T, Albert M, Hyman B, Petersen R, Younkin S, Sano M, Wisniewski T, Vassar R, Schneider J, Henderson V, Roberson E, DeCarli C, LaFerla F, Brewer J, Swerdlow R, Van Eldik L, Hamilton-Nelson K, Paulson H, Naj A, Lopez O, Chui H, Crane P, Grabowski T, Kukull W, Asthana S, Craft S, Strittmatter S, Cruchaga C, Leverenz J, Goate A, Kamboh MI, George-Hyslop PS, Valladares O, Kuzma A, Cantwell L, Riemenschneider M, Morris J, Slifer S, Dalmasso C, Castillo A, Küçükali F, Peters O, Schneider A, Dichgans M, Rujescu D, Scherbaum N, Deckert J, Riedel-Heller S, Hausner L, Molina-Porcel L, Düzel E, Grimmer T, Wiltfang J, Heilmann-Heimbach S, Moebus S, Tegos T, Scarmeas N, Dols-Icardo O, Moreno F, Pérez-Tur J, Bullido MJ, Pastor P, Sánchez-Valle R, Álvarez V, Boada M, García-González P, Puerta R, Mir P, Real LM, Piñol-Ripoll G, García-Alberca JM, Royo JL, Rodriguez-Rodriguez E, Soininen H, de Mendonça A, Mehrabian S, Traykov L, Hort J, Vyhnalek M, Thomassen JQ, Pijnenburg YAL, Holstege H, van Swieten J, Ramakers I, Verhey F, Scheltens P, Graff C, Papenberg G, Giedraitis V, Boland A, Deleuze JF, Nicolas G, Dufouil C, Pasquier F, Hanon O, Debette S, Grünblatt E, Popp J, Ghidoni R, Galimberti D, Arosio B, Mecocci P, Solfrizzi V, Parnetti L, Squassina A, Tremolizzo L, Borroni B, Nacmias B, Spallazzi M, Seripa D, Rainero I, Daniele A, Bossù P, Masullo C, Rossi G, Jessen F, Fernandez V, Kehoe PG, Frikke-Schmidt R, Tsolaki M, Sánchez-Juan P, Sleegers K, Ingelsson M, Haines J, Farrer L, Mayeux R, Wang LS, Sims R, DeStefano A, Schellenberg GD, Seshadri S, Amouyel P, Williams J, van der Flier W, Ramirez A, Pericak-Vance M, Andreassen OA, Van Duijn C, Hiltunen M, Ruiz A, Dupuis J, Martin E, Lambert JC, Kunkle B, Bellenguez C

The Consortium for Clarity in ADRD Research Through Imaging (CLARiTI).
(2025 Jan)
Alzheimers Dement 21(1): e14383
Mormino EC, Biber SA, Rahman-Filipiak A, Arfanakis K, Clark L, Dage JL, Detre JA, Dickerson BC, Donohue MC, Kecskemeti S, Hohman TJ, Jagust WJ, Keene DC, Kukull W, Levendovszky SR, Rosen H, Thompson PM, Villemagne VL, Wolk DA, Okonkwo OC, Rabinvovici GD, Rivera-Mindt M, Foroud T, Johnson SC

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