Faculty
Education
PhD Epidemiology, University of Washington, 1983
MS Psychology, Western Washington University, 1974
Contact
Box 357236
Dept. of Epidemiology
1959 NE Pacific Street
Health Sciences, F-261G
Seattle, WA 98195
Dept. of Epidemiology
1959 NE Pacific Street
Health Sciences, F-261G
Seattle, WA 98195
National Alzheimer's Coordinating Center
Box 354983
4311 11th Avenue NE #300
Seattle, WA 98105
Box 354983
4311 11th Avenue NE #300
Seattle, WA 98105
Research Areas
Research Interests
Dr Kukull's research is principally in the neurodegenerative, vascular and other conditions causing dementia and cognitive impairment. These conditions include Alzheimer's disease, Parkinson's/Lewy body disease, frontotemporal lobar degeneration, and cerebrovascular disease. Since 1999, as Director and PI of the National Alzheimer's Coordinating Center [U01AG016976], he is closely tied to the ~30 Alzheimer's Disease Centers nationwide, funded by National Institute on Aging. In addition to NACC work, he is an investigator with a number of other NIH grants.
Recent Publications (PubMed)
GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia.
(2024 Nov)
Nat Genet 56(11): 2407-2421
Shade LMP, Katsumata Y, Abner EL, Aung KZ, Claas SA, Qiao Q, Heberle BA, Brandon JA, Page ML, Hohman TJ, Mukherjee S, Mayeux RP, Farrer LA, Schellenberg GD, Haines JL, Kukull WA, Nho K, Saykin AJ, Bennett DA, Schneider JA, National Alzheimer’s Coordinating Center, Ebbert MTW, Nelson PT, Fardo DW
(2024 Nov)
Nat Genet 56(11): 2407-2421
Shade LMP, Katsumata Y, Abner EL, Aung KZ, Claas SA, Qiao Q, Heberle BA, Brandon JA, Page ML, Hohman TJ, Mukherjee S, Mayeux RP, Farrer LA, Schellenberg GD, Haines JL, Kukull WA, Nho K, Saykin AJ, Bennett DA, Schneider JA, National Alzheimer’s Coordinating Center, Ebbert MTW, Nelson PT, Fardo DW
Fazekas scale magnetic resonance imaging assessment in Alzheimer's disease and primary age-related tauopathy.
(2024 Sep 26)
Neuroradiology
Quintas-Neves M, Almeida FC, Gauthreaux K, Teylan MA, Mock CN, Kukull WA, Crary JF, Oliveira TG
(2024 Sep 26)
Neuroradiology
Quintas-Neves M, Almeida FC, Gauthreaux K, Teylan MA, Mock CN, Kukull WA, Crary JF, Oliveira TG
Field-of-view extension for brain diffusion MRI via deep generative models.
(2024 Jul)
J Med Imaging (Bellingham) 11(4): 044008
Gao C, Bao S, Kim ME, Newlin NR, Kanakaraj P, Yao T, Rudravaram G, Huo Y, Moyer D, Schilling K, Kukull WA, Toga AW, Archer DB, Hohman TJ, Landman BA, Li Z
(2024 Jul)
J Med Imaging (Bellingham) 11(4): 044008
Gao C, Bao S, Kim ME, Newlin NR, Kanakaraj P, Yao T, Rudravaram G, Huo Y, Moyer D, Schilling K, Kukull WA, Toga AW, Archer DB, Hohman TJ, Landman BA, Li Z
Evolution of white matter hyperintensity segmentation methods and implementation over the past two decades; an incomplete shift towards deep learning.
(2024 Jul 31)
Brain Imaging Behav
Rahmani M, Dierker D, Yaeger L, Saykin A, Luckett PH, Vlassenko AG, Owens C, Jafri H, Womack K, Fripp J, Xia Y, Tosun D, Benzinger TLS, Masters CL, Lee JM, Morris JC, Goyal MS, Strain JF, ADOPIC, ADNI Investigators, Kukull W, Weiner M, Biostats, Database and Bioinformatics, Burnham S, CoxDoecke TJ, Fedyashov V, Fripp J, Shishegar R, Xiong C, Marcus D, Raniga P, Li S, Cognition, Aschenbrenner A, Hassenstab J, Lim YY, Maruff P, Sohrabi H, Robertson J, Markovic S, Imaging, Bourgeat P, Doré V, Mayo CJ, Mussoumzadeh P, Rowe C, Villemagne V, CSF and Blood, Bateman R, Fowler C, Li QX, Martins R, Schindler S, Shaw L, Genetics, Cruchaga C, Harari O, Laws S, Porter T, O'Brien E, Neuropathology, Perrin R, NACC, Kukull W, DIAN, Bateman R, McDade E, Cerebrovascular Disease (CVD) Risk, Jack C, Morris J, Yassi N, Hippocampal Sclerosis (HS-TDP43) Risk, Bourgeat P, Perrin R, Roberts B, Villemagne V, Artificial Intelligence and Machine Learning, Fedyashov V, Goudey B
(2024 Jul 31)
Brain Imaging Behav
Rahmani M, Dierker D, Yaeger L, Saykin A, Luckett PH, Vlassenko AG, Owens C, Jafri H, Womack K, Fripp J, Xia Y, Tosun D, Benzinger TLS, Masters CL, Lee JM, Morris JC, Goyal MS, Strain JF, ADOPIC, ADNI Investigators, Kukull W, Weiner M, Biostats, Database and Bioinformatics, Burnham S, CoxDoecke TJ, Fedyashov V, Fripp J, Shishegar R, Xiong C, Marcus D, Raniga P, Li S, Cognition, Aschenbrenner A, Hassenstab J, Lim YY, Maruff P, Sohrabi H, Robertson J, Markovic S, Imaging, Bourgeat P, Doré V, Mayo CJ, Mussoumzadeh P, Rowe C, Villemagne V, CSF and Blood, Bateman R, Fowler C, Li QX, Martins R, Schindler S, Shaw L, Genetics, Cruchaga C, Harari O, Laws S, Porter T, O'Brien E, Neuropathology, Perrin R, NACC, Kukull W, DIAN, Bateman R, McDade E, Cerebrovascular Disease (CVD) Risk, Jack C, Morris J, Yassi N, Hippocampal Sclerosis (HS-TDP43) Risk, Bourgeat P, Perrin R, Roberts B, Villemagne V, Artificial Intelligence and Machine Learning, Fedyashov V, Goudey B
Sex, racial, and APOE-ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease.
(2024 Jun 12)
bioRxiv
Peterson A, Sathe A, Zaras D, Yang Y, Durant A, Deters KD, Shashikumar N, Pechman KR, Kim ME, Gao C, Khairi NM, Li Z, Yao T, Huo Y, Dumitrescu L, Gifford KA, Wilson JE, Cambronero F, Risacher SL, Beason-Held LL, An Y, Arfanakis K, Erus G, Davatzikos C, Tosun D, Toga AW, Thompson PM, Mormino EC, Zhang P, Schilling K, Alzheimer’s Disease Neuroimaging Initiative (ADNI), BIOCARD Study Team, Alzheimer’s Disease Sequencing Project (ADSP), Albert M, Kukull W, Biber SA, Landman BA, Johnson SC, Schneider J, Barnes LL, Bennett DA, Jefferson AL, Resnick SM, Saykin AJ, Hohman TJ, Archer DB
(2024 Jun 12)
bioRxiv
Peterson A, Sathe A, Zaras D, Yang Y, Durant A, Deters KD, Shashikumar N, Pechman KR, Kim ME, Gao C, Khairi NM, Li Z, Yao T, Huo Y, Dumitrescu L, Gifford KA, Wilson JE, Cambronero F, Risacher SL, Beason-Held LL, An Y, Arfanakis K, Erus G, Davatzikos C, Tosun D, Toga AW, Thompson PM, Mormino EC, Zhang P, Schilling K, Alzheimer’s Disease Neuroimaging Initiative (ADNI), BIOCARD Study Team, Alzheimer’s Disease Sequencing Project (ADSP), Albert M, Kukull W, Biber SA, Landman BA, Johnson SC, Schneider J, Barnes LL, Bennett DA, Jefferson AL, Resnick SM, Saykin AJ, Hohman TJ, Archer DB
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In the News
Population neuroscience approach to dementia research
ASPPH, 03/08/2018
ASPPH, 03/08/2018
National Alzheimer's Coordinating Center Receives $19.7 Million Grant
ASPPH Friday Letter, 08/28/2014
ASPPH Friday Letter, 08/28/2014
Close Up July 2014: Walter Kukull
SPH News, 06/26/2014
SPH News, 06/26/2014
UW Work Contributes To Largest International Study of Alzheimer's Genes
UW Today, 10/28/2013
UW Today, 10/28/2013