Renee Heffron

Associate Professor, Epidemiology
Associate Professor, Global Health



PhD Epidemiology, University of Washington, 2012
MPH Tulane University, 2004



Ninth and Jefferson Building
325 Ninth Avenue, Box 359927
Seattle, WA 98104


Dr. Heffron is a member of the faculty of Global Health and jointly appointed in Epidemiology and she has been working within the International Clinical Research Center since 2008. Her research, teaching, and mentoring focuses on advancing the field of HIV prevention, often by leveraging intersections with reproductive health. Currently, she has been particularly focused on oral PrEP and utilizing a variety of methods from the fields of clinical epidemiology and implementation science, including clinical trials and observational studies, causal inference, qualitative research, to study effectiveness and optimizing delivery of oral PrEP among young women and HIV serodiscordant couples in sub-Saharan Africa. For all of this work, she collaborates extensively with colleagues in Kenya, Uganda, South Africa, and Lesotho. She teaches HIV/STI Research Methods in Spring Quarter and mentors PhD and MPH students from her departments.Renee Heffron, MPH, PhD, focuses on epidemiologic questions that bridge the areas of reproductive health and HIV prevention including recent work on hormonal contraception and pregnancy and their effect on HIV risk. Dr. Heffron collaborates extensively with investigators in Kenya and Uganda, as well as colleagues in the International Clinical Research Center at UW.

Research Interests

  • HIV prevention
  • PrEP
  • ART
  • HIV and pregnancy
  • HIV and hormonal contraception

Recent Publications (PubMed)

Comparison of Female Genital Tract Cytokine and Microbiota Signatures Induced by Initiation of Intramuscular DMPA and NET-EN Hormonal Contraceptives - a Prospective Cohort Analysis.
Front Immunol 12(): 760504
Dabee S, Tanko RF, Brown BP, Bunjun R, Balle C, Feng C, Konstantinus IN, Jaumdally SZ, Onono M, Nair G, Palanee-Phillips T, Gill K, Baeten JM, Bekker LG, Passmore JS, Heffron R, Jaspan HB, Happel AU

Incidence of herpes simplex virus type 2 infection among African women using depot medroxyprogesterone acetate, a copper intrauterine device, or a levonorgestrel implant for contraception: a nested randomized trial.
(2021 Dec 15)
Clin Infect Dis
Mugo NR, Stalter RM, Heffron R, Rees H, Scoville CW, Morrison C, Kourtis AP, Bukusi E, Beksinka M, Philip NM, Beesham I, Deese J, Edward V, Donnell D, Baeten JM, Evidence for Contraceptive Options and HIV Outcomes (ECHO) Trial Consortium.

Adolescent girls and young women's PrEP-user journey during an implementation science study in South Africa and Kenya.
PLoS One 16(10): e0258542
Rousseau E, Katz AWK, O'Rourke S, Bekker LG, Delany-Moretlwe S, Bukusi E, Travill D, Omollo V, Morton JF, O'Malley G, Haberer JE, Heffron R, Johnson R, Celum C, Baeten JM, van der Straten A

Recent Advances and New Challenges in Cisgender Women's Gynecologic and Obstetric Health in the Context of HIV.
(2021 Sep 1)
Clin Obstet Gynecol 64(3): 475-490
Deese J, Heffron R, Jaspan H, Masson L, Smit JA, Sibeko S

ART initiation among women newly diagnosed with HIV in a contraceptive trial in sub-Saharan Africa.
(2021 Jun 27)
Beesham I, Issema R, Palanee-Phillips T, Onono M, Evans S, Beksinska M, Ahmed K, Kasaro MP, Batting J, Deese J, Dlamini L, Yankurije B, Thomas KK, Heffron R, *ECHO Trial Consortium.

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