Paul K. Drain

Adjunct Associate Professor, Epidemiology
Associate Professor, Global Health



MD Medicine (MD), University of Washington, 2007
MPH Epidemiology and International Health, University of Washington, 2001
BA Microbiology, Miami University (Ohio), 1996



Box 359927
325 Ninth Ave
Seattle, WA 98104
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Paul Drain’s research group focuses on development, evaluation and implementation of diagnostic testing and clinic-based screening, including novel point-of-care technologies, to improve clinical care and patient-centered outcomes for tuberculosis and HIV in resource-limited settings. He is the Director of Clinical and Translational Research at the International Center for Clinical Research (ICRC) and the Director of the Clinical and Translational Science Core within the Tuberculosis Research Advancement Center (SEA-TRAC) at the University of Washington. He currently teaches “Global Population Health” in the School of Public Health, and teaches “Clinical Global Health and Social Medicine” for medical students. He research has been supported by several institutes of the National Institutes of Health, the Infectious Disease Society of America, Bill and Melinda Gates Foundation, the US Centers for Disease Control and Prevention, the US Department of Defense, the NIH Center for AIDS Research, as well as several corporations. He has authored several global health books and received awards from the Global Health Education Consortium, the Infectious Disease Society of America, and a Faculty Teaching Award from Harvard Medical School. Paul completed his medicine training at Stanford University and his infectious disease training at Massachusetts General Hospital and Brigham and Women’s Hospital at Harvard Medical School in Boston.

Research Interests

  • Infectious diseases
  • Improve the diagnosis and treatment for tuberculosis, HIV, and HIV-related opportunistic infections

Research Group Website

Recent Publications (PubMed)

The elusive allure of a rapid host blood signature for tuberculosis disease.
(2024 Feb 14)
J Clin Microbiol 62(2): e0128923
Drain PK, Dalmat RR

Correction: Performance of novel antibodies for lipoarabinomannan to develop diagnostic tests for Mycobacterium tuberculosis.
PLoS One 19(1): e0297828
Cantera JL, Lillis LM, Peck RB, Moreau E, Schouten JA, Davis P, Zheng RB, Lowary TL, Drain PK, Andama A, Pinter A, Kawasaki M, Källenius G, Sundling C, Dobos KM, Flores D, Chatterjee D, Murphy E, Halas OR, Boyle DS

Urine tenofovir and dried blood spot tenofovir diphosphate concentrations and viraemia in people taking efavirenz and dolutegravir based antiretroviral therapy.
(2023 Dec 19)
Dorward J, Govender K, Moodley P, Lessells R, Samsunder N, Sookrajh Y, Fanshawe TR, Turner PJ, Butler CC, Drain PK, Hayward GN, Garrett N

No extraction? No problem. Direct to PCR processing of tongue swabs for diagnosis of tuberculosis disease as an alternative to sputum collection.
(2024 Jan 11)
Microbiol Spectr 12(1): e0310723
Ahls CL, Emsweller D, Helfers SJ, Niu X, Wilson D, Padgett LR, Drain PK

A Call to Improve Usability, Accuracy, and Equity of Self-Testing for COVID-19 and Other Rapid Diagnostic Tests.
Health Equity 7(1): 731-734
Drain PK, Adams AK, Kessler L, Thompson M

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