Faculty

Silvia de Sanjose Llongueras

Affiliate Professor, Epidemiology


Education

MD Medicine & Surgery, University of Barcelona, 1980
MSc Epidemiology, London School of Hygiene & Tropical Medicine (UK), 1986
PhD Epidemiology, London School of Hygiene & Tropical Medicine (UK), 1989

Contact


ISGlobal
Barcelona,

Bio

Dr. de Sanjose is a Medical Doctor from the University of Barcelona, Spain and PhD from the London University, UK. She is an epidemiologist working on HPV-related diseases for over 35 years. She has been employed at WHO- IARC, at the Catalan Institute of Oncology in Barcelona, Spain, at PATH in Seattle, and at the USA National Cancer Institute. She is the Past President of the International PapillomaVirus Society (2015-18). She is an associated researcher at ISGlobal in Barcelona, Spain and has a grant with Dr Margaret Madeline and Ann Durr from the Fred Hutch.

She is interested in the pathways of cervical cancer prevention and all HPV-related cancers through vaccination and secondary prevention and adequate management. She co-leads a Moonshoot-related project, the PAVE project, which primarily emphasizes the utilization of HPV detection through self-sampling, extended genotype information, and, for women who test positive for HPV, the automated evaluation of cervical images using AI-based solutions to enhance visual assessment with acetic acid. She is involved in shaping the World Health Organization's living guidelines for cervical cancer screening and the Code of Cancer Prevention for Europe.

Research Areas

Research Interests

I am interested in the pathways of cervical cancer prevention and all HPV-related cancers through vaccination and secondary prevention and adequate management. In particular I am involved in improving cervical cancer screening in poor resource settings.

Recent Publications (PubMed)

Role of Reserve Cells in Metaplasia and the Development of Human Papillomavirus-Associated High-Grade Squamous Intraepithelial Lesions at the Cervical Transformation Zone.
(2025 Apr 9)
Lab Invest 105(7): 104166
Aiyenuro A, Griffin H, Schichl K, Omar T, Ordi J, Kelly H, Walker C, Pino MD, Desai K, de Sanjosé S, Schiffman M, Doorbar J
Initial evaluation of a new cervical screening strategy combining human papillomavirus genotyping and automated visual evaluation: the Human Papillomavirus-Automated Visual Evaluation Consortium.
(2025 Mar 18)
J Natl Cancer Inst
Befano B, Kalpathy-Cramer J, Egemen D, Inturrisi F, Jeronimo J, Rodríguez AC, Campos N, Cremer M, Ribeiro A, Ajenifuja KO, Goldstein A, Haider A, Yeates K, Madeleine M, Norris T, Figueroa J, Alfaro K, Raiol T, Adepiti C, Norman J, Chilinda GK, Mchome B, Donastorg Y, Dlamini X, Conzuelo G, Banjo AA, Chone P, Mremi A, Benitez A, Rosberger Z, Vantha T, Prieto-Egido I, Boyd-Morin J, Clark C, Kinder S, Wentzensen N, Desai K, Perkins R, de Sanjosé S, Schiffman M, PAVE Consortium
Generalizable deep neural networks for image quality classification of cervical images.
(2025 Feb 21)
Sci Rep 15(1): 6312
Ahmed SR, Befano B, Egemen D, Rodriguez AC, Desai KT, Jeronimo J, Ajenifuja KO, Clark C, Perkins R, Campos NG, Inturrisi F, Wentzensen N, Han P, Guillen D, Norman J, Goldstein AT, Madeleine MM, Donastorg Y, Schiffman M, de Sanjose S, Kalpathy-Cramer J, PAVE Study Group
Acceptability and somatic mutations in cervicovaginal self-sampling for early endometrial cancer detection in women with Lynch syndrome.
(2025 May 1)
Int J Cancer 156(9): 1791-1801
Peremiquel-Trillas P, Martínez JM, Paytubi S, Frias-Gomez J, Pelegrina B, Marin F, Benavente Y, Ibáñez R, Barahona M, Fernandez-Gonzalez S, Cárdenas L, Taltavull A, Darder E, de Sanjosé S, Widschwendter M, Matias-Guiu X, Bosch X, Pineda M, Ponce J, Brunet J, Alemany L, Costas L
Long-Term Reassurance with Negative High-Risk Human Papillomavirus (HR-HPV) and Clear Margins After Large Loop Excision of the Transformation Zone (LLETZ).
(2025 Feb 1)
Cancers (Basel) 17(3):
Heydari F, de Sanjosé S, Peñafiel Muñoz J, Fernández-Montolí ME
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