Faculty

Silvia de Sanjose Llongueras

Affiliate Professor, Epidemiology

206-285-3500
sdesanjose@path.org

Education

MD Medicine & Surgery, University of Barcelona, 1980
MSc Epidemiology, London School of Hygiene & Tropical Medicine (UK), 1986
PhD Epidemiology, London School of Hygiene & Tropical Medicine (UK), 1989

Contact

206-285-3500
sdesanjose@path.org

PATH
Reproductive Health Global Program
2201 Westlake Avenue
Seattle, WA 98121

Research Interests

As medical epidemiologist, I have been involved in multiple research projects that relate to HPV and cancer, including the first studies showing the causal association of the virus with cancer, such as the IARC multi-centric case-control study on invasive cervical cancer, the IARC multi-centric prevalence study, the ICO/HPV information center, and several other projects related to HPV in various areas around the world. Among these projects, I have coordinated the ICO International genotype studies (RIS HPV TT, VVAP) on HPV-related cancers including cervical cancer, vulva, vagina, anal and penile cancers that involve the collaboration of more  than 50 countries.
 
I have been involved in research projects exploring the relationship between HIV and HPV and  have been external advisor in the HPV in Africa Research Partnership (HARP) study carried out in Burkina Faso and South Africa, and have explores the association of antiretroviral therapy with high-risk human papillomavirus, cervical intraepithelial neoplasia, and invasive cervical cancer in women living with  HIV.
 
I have mentored 16 PhD, at the London University, McGill University, University of Barcelona and Pompeu Fabra University. I am actually supervising one PhD student and one Marie Curie grantee.

I am the Director of the Scale-Up project  aiming to  introduce and scale-up efficient and high-quality cervical cancer screening in low- and middle-income countries (LMICs); this project is mostly based in Central American region. I am also the currently  coordinating a srtudy in Honduras that explores thermal ablation as an accessible and highly-effective treatment approach for pre-neoplasic lesions in LMICs.  I am co-chairing the forthcoming IPVC 2020 conference in Barcelona.

Recent Publications (PubMed)

IPVS policy statement on HPV nucleic acid testing guidance for those utilising/considering HPV as primary precancer screening: Quality assurance and quality control issues.
(2023 Feb)
J Clin Virol 159(): 105349
Garland SM, Iftner T, Cuschieri K, Kaufmann AM, Arbyn M, de Sanjose S, Poljak M, Dillner J, Unger ER, IPVS Policy Committee

Improving the repeatability of deep learning models with Monte Carlo dropout.
(2022 Nov 18)
NPJ Digit Med 5(1): 174
Lemay A, Hoebel K, Bridge CP, Befano B, De Sanjosé S, Egemen D, Rodriguez AC, Schiffman M, Campbell JP, Kalpathy-Cramer J

Image Quality Classification for Automated Visual Evaluation of Cervical Precancer.
(2022 Sep)
Milland Workshop (2022) 13559(): 206-217
Xue Z, Angara S, Guo P, Rajaraman S, Jeronimo J, Rodriguez AC, Alfaro K, Charoenkwan K, Mungo C, Domgue JF, Wentzensen N, Desai KT, Ajenifuja KO, Wikström E, Befano B, de Sanjosé S, Schiffman M, Antani S

Acting on the call for cervical cancer elimination: Planning tools for low- and middle- income countries to increase the coverage and effectiveness of screening and treatment.
(2022 Oct 14)
BMC Health Serv Res 22(1): 1246
Herrick T, Thomson KA, Shin M, Gannon S, Tsu V, de Sanjosé S

Diagnostic accuracy of cervical cancer screening strategies for high-grade cervical intraepithelial neoplasia (CIN2+/CIN3+) among women living with HIV: A systematic review and meta-analysis.
(2022 Nov)
EClinicalMedicine 53(): 101645
Kelly H, Jaafar I, Chung M, Michelow P, Greene S, Strickler H, Xie X, Schiffman M, Broutet N, Mayaud P, Dalal S, Arbyn M, de Sanjosé S

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