Silvia de Sanjose Llongueras

Affiliate Professor, Epidemiology



MD Medicine & Surgery, University of Barcelona, 1980
MSc Epidemiology, London School of Hygiene & Tropical Medicine (UK), 1986
PhD Epidemiology, London School of Hygiene & Tropical Medicine (UK), 1989



Reproductive Health Global Program
2201 Westlake Avenue
Seattle, WA 98121

Research Interests

As medical epidemiologist, I have been involved in multiple research projects that relate to HPV and cancer, including the first studies showing the causal association of the virus with cancer, such as the IARC multi-centric case-control study on invasive cervical cancer, the IARC multi-centric prevalence study, the ICO/HPV information center, and several other projects related to HPV in various areas around the world. Among these projects, I have coordinated the ICO International genotype studies (RIS HPV TT, VVAP) on HPV-related cancers including cervical cancer, vulva, vagina, anal and penile cancers that involve the collaboration of more  than 50 countries.
I have been involved in research projects exploring the relationship between HIV and HPV and  have been external advisor in the HPV in Africa Research Partnership (HARP) study carried out in Burkina Faso and South Africa, and have explores the association of antiretroviral therapy with high-risk human papillomavirus, cervical intraepithelial neoplasia, and invasive cervical cancer in women living with  HIV.
I have mentored 16 PhD, at the London University, McGill University, University of Barcelona and Pompeu Fabra University. I am actually supervising one PhD student and one Marie Curie grantee.

I am the Director of the Scale-Up project  aiming to  introduce and scale-up efficient and high-quality cervical cancer screening in low- and middle-income countries (LMICs); this project is mostly based in Central American region. I am also the currently  coordinating a srtudy in Honduras that explores thermal ablation as an accessible and highly-effective treatment approach for pre-neoplasic lesions in LMICs.  I am co-chairing the forthcoming IPVC 2020 conference in Barcelona.

Recent Publications (PubMed)

The combined finding of HPV 16, 18, or 45 and cytologic Atypical Glandular Cells (AGC) indicates a greatly elevated risk of in situ and invasive cervical adenocarcinoma.
(2023 May 25)
Gynecol Oncol 174(): 253-261
Schiffman M, Mirabello L, Egemen D, Befano B, Xiao Y, Wentzensen N, Raine-Bennett T, Nayar R, Cheung LC, Rositch A, Beaty T, Perkins RB, de Sanjose S, Lorey T, Castle PE, Burk RD

Do GWAS-Identified Risk Variants for Chronic Lymphocytic Leukemia Influence Overall Patient Survival and Disease Progression?
(2023 Apr 28)
Int J Mol Sci 24(9):
Cabrera-Serrano AJ, Sánchez-Maldonado JM, Ter Horst R, Macauda A, García-Martín P, Benavente Y, Landi S, Clay-Gilmour A, Niazi Y, Espinet B, Rodríguez-Sevilla JJ, Pérez EM, Maffei R, Blanco G, Giaccherini M, Cerhan JR, Marasca R, López-Nevot MÁ, Chen-Liang T, Thomsen H, Gámez I, Campa D, Moreno V, de Sanjosé S, Marcos-Gragera R, García-Álvarez M, Dierssen-Sotos T, Jerez A, Butrym A, Norman AD, Luppi M, Slager SL, Hemminki K, Li Y, Berndt SI, Casabonne D, Alcoceba M, Puiggros A, Netea MG, Försti A, Canzian F, Sainz J

Cost-effectiveness analysis of molecular testing in minimally invasive samples to detect endometrial cancer in women with postmenopausal bleeding.
(2023 May 10)
Br J Cancer
Peremiquel-Trillas P, Gómez D, Martínez JM, Fernández-González S, Frias-Gomez J, Paytubi S, Pelegrina B, Pineda M, Brunet J, Ponce J, Matias-Guiu X, Bosch X, de Sanjosé S, Bruni L, Alemany L, Costas L, Díaz M

Use of risk-based cervical screening programs in resource-limited settings.
(2023 Jun)
Cancer Epidemiol 84(): 102369
Perkins RB, Smith DL, Jeronimo J, Campos NG, Gage JC, Hansen N, Rodriguez AC, Cheung LC, Egemen D, Befano B, Novetsky AP, Martins S, Kalpathy-Cramer J, Inturrisi F, Ahmed SR, Marcus J, Wentzensen N, de Sanjose S, Schiffman M

COVID-19 as a catalyst for reimagining cervical cancer prevention.
(2023 Apr 18)
Elife 12():
Luckett R, Feldman S, Woo YL, Moscicki AB, Giuliano AR, de Sanjosé S, Kaufmann AM, Leung SOA, Garcia F, Chan K, Bhatla N, Stanley M, Brotherton J, Palefsky J, Garland S, International Papillomavirus Society (IPVS) Policy Committee

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