Helen Y Chu

Adjunct Professor, Epidemiology
Professor, Medicine - Allergy and Infectious Dis.
Adjunct Professor, Global Health



MPH Epidemiology, University of Washington, 2012
MD Medicine, Duke University Medical Center, Durham, NC, 2005
BA Cornell University, 2001



Box 359779
R&T Bldg, 300 9th Ave
Seattle, WA 98104
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Research Interests

Dr. Chu's research is focused on maternal immunization, in particular vaccines against influenza and respiratory syncytial virus (RSV). She studies the virologic and immunologic correlates of protection from respiratory viral infections in pregnant women, infants, and older adults, and performs clinical trials of vaccine candidates in both domestic and international sites, including Nepal and Bangladesh. She has developed immunologic assays to study transplacental transfer and decay kinetics of RSV antibody, and nosocomial and household transmission of respiratory viruses by genotypic analysis and molecular sequencing.

Recent Publications (PubMed)

Neutralization, effector function and immune imprinting of Omicron variants.
(2023 Sep)
Nature 621(7979): 592-601
Addetia A, Piccoli L, Case JB, Park YJ, Beltramello M, Guarino B, Dang H, de Melo GD, Pinto D, Sprouse K, Scheaffer SM, Bassi J, Silacci-Fregni C, Muoio F, Dini M, Vincenzetti L, Acosta R, Johnson D, Subramanian S, Saliba C, Giurdanella M, Lombardo G, Leoni G, Culap K, McAlister C, Rajesh A, Dellota E Jr, Zhou J, Farhat N, Bohan D, Noack J, Chen A, Lempp FA, Quispe J, Kergoat L, Larrous F, Cameroni E, Whitener B, Giannini O, Cippà P, Ceschi A, Ferrari P, Franzetti-Pellanda A, Biggiogero M, Garzoni C, Zappi S, Bernasconi L, Kim MJ, Rosen LE, Schnell G, Czudnochowski N, Benigni F, Franko N, Logue JK, Yoshiyama C, Stewart C, Chu H, Bourhy H, Schmid MA, Purcell LA, Snell G, Lanzavecchia A, Diamond MS, Corti D, Veesler D

Anamnestic humoral correlates of immunity across SARS-CoV-2 variants of concern.
(2023 Aug 31)
mBio 14(4): e0090223
McNamara RP, Maron JS, Boucau J, Roy V, Webb NE, Bertera HL, Barczak AK, Positives Study Staff T, Franko N, Logue JK, Kemp M, Li JZ, Zhou L, Hsieh CL, McLellan JS, Siedner MJ, Seaman MS, Lemieux JE, Chu HY, Alter G

Risk of Subsequent Respiratory Virus Detection After Primary Virus Detection in a Community Household Study - King County, Washington 2019-2021.
(2023 Aug 2)
J Infect Dis
Heimonen J, Chow EJ, Wang Y, Hughes JP, Rogers J, Emanuels A, O'Hanlon J, Han PD, Wolf CR, Logue JK, Ogokeh CE, Rolfes MA, Uyeki TM, Starita L, Englund JA, Chu HY

Streptococcus pneumoniae nasal carriage patterns with and without common respiratory virus detections in households in Seattle, WA, USA before and during the COVID-19 pandemic.
Front Pediatr 11(): 1198278
Bennett JC, Emanuels A, Heimonen J, O'Hanlon J, Hughes JP, Han PD, Chow EJ, Ogokeh CE, Rolfes MA, Lockwood CM, Pfau B, Uyeki TM, Shendure J, Hoag S, Fay K, Lee J, Sibley TR, Rogers JH, Starita LM, Englund JA, Chu HY

Previous Health Care Experiences' Influence on Health Care Perceptions Among Residents of Six Homeless Shelters in Seattle, Washington, July-October 2021.
(2023 Summer)
J Patient Cent Res Rev 10(3): 111-120
Meehan AA, Cox SN, Thuo NB, Rogers JH, Link AC, Martinez MA, Lo NK, Manns BJ, Rolfes MA, Chow EJ, Chu HY, Mosites E, Al Achkar M

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