Faculty

Helen Y Chu

Professor, Epidemiology
Professor, Medicine - Allergy and Infectious Dis.
Program Lead, Infectious Disease, Brotman Baty Institute, Medicine - Allergy and Infectious Dis.
Term Professorship, Medicine - Allergy and Infectious Dis.
Associate Dean for Research, School of Public Health


Education

MPH Epidemiology, University of Washington, 2012
MD Medicine, Duke University Medical Center, Durham, NC, 2005
BA Cornell University, 2001

Research Areas

Research Interests

Dr. Chu's research is focused on maternal immunization, in particular vaccines against influenza and respiratory syncytial virus (RSV). She studies the virologic and immunologic correlates of protection from respiratory viral infections in pregnant women, infants, and older adults, and performs clinical trials of vaccine candidates in both domestic and international sites, including Nepal and Bangladesh. She has developed immunologic assays to study transplacental transfer and decay kinetics of RSV antibody, and nosocomial and household transmission of respiratory viruses by genotypic analysis and molecular sequencing.

Recent Publications (PubMed)

Nirmatrelvir-ritonavir targeting viral persistence in post-COVID-19 condition (long COVID) in the USA (RECOVER-VITAL): a randomised, double-blind, placebo-controlled, phase 2 trial.
(2026 Aug 31)
Lancet Infect Dis
Baden LR, Shah NS, Liu STH, Cohen J, Moy J, Kumar A, McComsey GA, Chen P, Floris-Moore M, Singer NG, Fernandez I, Slandzicki AJ, Wiley Z, Kadl A, Kaminsky DA, Hsu H, Walker TA, Hope AA, Ostrosky-Zeichner L, Goldman JD, Peluso MJ, Patterson TF, Parthasarathy S, Mullington JM, Bolin P Jr, Jolley SE, Krishnan JA, Castro M, Hodder SL, Pemu P, Chu HY, Risbano MG, Jerath MR, Mylonakis E, Hurt RT, Alicic R, Azad NS, Sala MA, Harkins MS, Parsonnet J, Stafford N, Robinson P, Hussain S, Qiao X, Hawk ST, Lillestol M, Erdmann N, Gebo KA, Sudhindra P, Sassine J, Marshall GD, Chatterjee T, Morse CG, Kedar E, Stringer WW, Frontera JA, Jordan M, Blaskewicz C, Santana JL, Foot RA, Wongtrakool C, McCarthy MW, Mehari A, Amon A, Cohen AK, Jain N, Maughan C, Lindsay D, Olson R, Broderick S, Rowe P, O'Brien SM, Walt DR, Levy BD, Jason LA, Low PA, Shibao CA, Make B, Bateman L, Redline S, Knopman D, Hernandez AF, Nolen TL, Reist C, Berdan L, Whitley R, Zimmerman KO, RECOVER-VITAL Clinical Trial Group
A Hat Trick for RSV Vaccines - Prevention of Disease, Hospitalization, and Beyond.
(2026 Aug 29)
NEJM Evid
Chu HY, Erlandson K
Household Transmission of Human Metapneumovirus and Human Parainfluenza Viruses 1-4 in the United States, 2022-2024.
(2026 Aug 3)
medRxiv
Roychoudhury P, Elias-Warren A, Wetzler E, Kim HG, Kong K, Xie H, Spring C, Mills MG, Harteloo A, Frivold C, Hollcroft M, Drummond M, Hatchie T, Clark E, Ehmen B, Han PD, Gamboa L, Grindstaff S, Stone J, Hoffman KL, Greninger AL, Starita LM, Lockwood C, Englund JA, Weil AA, Reich SL, Mularski RA, Schmidt MA, Kuntz JL, Naleway AL, Chu HY
Crisis as Catalyst: The future of the NIH driving scientific discovery.
(2026 Jul 31)
J Infect Dis
Weil AA, Baker SM, Buckner FS, Gottlieb GS, Hybiske K, Koelle DM, Reid TB, Sabo MC, Seshadri C, Shah JA, Van Voorhis WC, Chu HY
Epidemiology of symptomatic respiratory viral codetections among children and adults in the United States: a post-hoc analysis of a prospective cohort study from 2022-2024.
(2026 Jul 30)
Clin Microbiol Infect
Erlianti CP, Wetzler EA, Weil AA, Naleway AL, Carone M, Chu HY
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