Faculty

Helen Chu

Adjunct Associate Professor, Epidemiology
Associate Professor, Medicine - Allergy and Infectious Dis.
Adjunct Associate Professor, Global Health

206-685-8702
helenchu@uw.edu

Education

MPH Epidemiology, University of Washington, 2012
MD Medicine, Duke University Medical Center, Durham, NC, 2005
BA Cornell University, 2001

Contact

206-685-8702
helenchu@uw.edu

Box 359779
R&T Bldg, 300 9th Ave
Seattle, WA 98104

Research Interests

Dr. Chu's research is focused on maternal immunization, in particular vaccines against influenza and respiratory syncytial virus (RSV). She studies the virologic and immunologic correlates of protection from respiratory viral infections in pregnant women, infants, and older adults, and performs clinical trials of vaccine candidates in both domestic and international sites, including Nepal and Bangladesh. She has developed immunologic assays to study transplacental transfer and decay kinetics of RSV antibody, and nosocomial and household transmission of respiratory viruses by genotypic analysis and molecular sequencing.

Recent Publications (PubMed)

Comparison of Symptoms and RNA Levels in Children and Adults With SARS-CoV-2 Infection in the Community Setting.
(2021 Jun 11)
JAMA Pediatr
Chung E, Chow EJ, Wilcox NC, Burstein R, Brandstetter E, Han PD, Fay K, Pfau B, Adler A, Lacombe K, Lockwood CM, Uyeki TM, Shendure J, Duchin JS, Rieder MJ, Nickerson DA, Boeckh M, Famulare M, Hughes JP, Starita LM, Bedford T, Englund JA, Chu HY

Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection.
(2021 Jun 8)
Sci Transl Med
Greaney AJ, Loes AN, Gentles LE, Crawford KHD, Starr TN, Malone KD, Chu HY, Bloom JD

Seroprevalence of SARS-CoV-2 antibodies in Seattle, Washington: October 2019-April 2020.
(2021)
PLoS One 16(5): e0252235
McCulloch DJ, Jackson ML, Hughes JP, Lester S, Mills L, Freeman B, Rasheed MAU, Thornburg NJ, Chu HY

Humoral immunogenicity of the seasonal influenza vaccine before and after CAR-T-cell therapy.
(2021 May 11)
medRxiv
Walti CS, Loes AN, Shuey K, Krantz EM, Boonyaratanakornkit J, Keane-Candib J, Loeffelholz T, Wolf CR, Taylor JJ, Gardner RA, Green DJ, Cowan AJ, Maloney DG, Turtle CJ, Pergam SA, Chu HY, Bloom JD, Hill JA

High-resolution profiling of pathways of escape for SARS-CoV-2 spike-binding antibodies.
(2021 May 27)
Cell 184(11): 2927-2938.e11
Garrett ME, Galloway J, Chu HY, Itell HL, Stoddard CI, Wolf CR, Logue JK, McDonald D, Weight H, Matsen FA 4th, Overbaugh J

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