Faculty

Helen Y Chu

Professor, Epidemiology
Professor, Medicine - Allergy and Infectious Dis.
Adjunct Professor, Global Health
Term Professorship, Medicine - Allergy and Infectious Dis.


Education

MPH Epidemiology, University of Washington, 2012
MD Medicine, Duke University Medical Center, Durham, NC, 2005
BA Cornell University, 2001

Research Areas

Research Interests

Dr. Chu's research is focused on maternal immunization, in particular vaccines against influenza and respiratory syncytial virus (RSV). She studies the virologic and immunologic correlates of protection from respiratory viral infections in pregnant women, infants, and older adults, and performs clinical trials of vaccine candidates in both domestic and international sites, including Nepal and Bangladesh. She has developed immunologic assays to study transplacental transfer and decay kinetics of RSV antibody, and nosocomial and household transmission of respiratory viruses by genotypic analysis and molecular sequencing.

Recent Publications (PubMed)

Absenteeism and Health Behavior Trends Associated With Acute Respiratory Illness Before and During the COVID-19 Pandemic in a Community Household Cohort, King County, Washington.
(2024 Aug)
AJPM Focus 3(4): 100248
Chung E, Wang Y, Chow EJ, Emanuels A, Heimonen J, Ogokeh CE, Rolfes MA, Hughes JP, Uyeki TM, Starita LM, Hoag S, Boeckh M, Englund JA, Chu HY, Seattle Flu Study Investigators
Age-dependent heterogeneity in the antigenic effects of mutations to influenza hemagglutinin.
(2024 Jul 16)
Cell Host Microbe
Welsh FC, Eguia RT, Lee JM, Haddox HK, Galloway J, Van Vinh Chau N, Loes AN, Huddleston J, Yu TC, Quynh Le M, Nhat NTD, Thi Le Thanh N, Greninger AL, Chu HY, Englund JA, Bedford T, Matsen FA 4th, Boni MF, Bloom JD
Spike deep mutational scanning helps predict success of SARS-CoV-2 clades.
(2024 Jul)
Nature 631(8021): 617-626
Dadonaite B, Brown J, McMahon TE, Farrell AG, Figgins MD, Asarnow D, Stewart C, Lee J, Logue J, Bedford T, Murrell B, Chu HY, Veesler D, Bloom JD
Antibody responses to respiratory syncytial virus: a population-based cross-sectional serological study in Southern China, 2021.
(2024 Jun 7)
Clin Microbiol Infect
Wang Q, Liu N, Wang Y, Ruckwardt TJ, Xu M, Wu J, Zhang J, Tong X, Zhou J, Lin J, Liang Y, Yang J, Yi L, Chu HY, Yu H
Evaluation of a novel university-based testing platform to increase access to SARS-CoV-2 testing during the COVID-19 pandemic in a cohort study.
(2024 Jun 4)
BMJ Open 14(6): e081837
Bennett JC, O'Hanlon J, Acker Z, Han PD, McDonald D, Wright T, Luiten KG, Regelbrugge L, McCaffrey KM, Pfau B, Wolf CR, Gottlieb GS, Hughes JP, Carone M, Starita LM, Chu HY, Weil AA
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