Faculty

Helen Y Chu

Professor, Epidemiology
Professor, Medicine - Allergy and Infectious Dis.
Adjunct Professor, Global Health
Term Professorship, Medicine - Allergy and Infectious Dis.


Education

MPH Epidemiology, University of Washington, 2012
MD Medicine, Duke University Medical Center, Durham, NC, 2005
BA Cornell University, 2001

Research Areas

Research Interests

Dr. Chu's research is focused on maternal immunization, in particular vaccines against influenza and respiratory syncytial virus (RSV). She studies the virologic and immunologic correlates of protection from respiratory viral infections in pregnant women, infants, and older adults, and performs clinical trials of vaccine candidates in both domestic and international sites, including Nepal and Bangladesh. She has developed immunologic assays to study transplacental transfer and decay kinetics of RSV antibody, and nosocomial and household transmission of respiratory viruses by genotypic analysis and molecular sequencing.

Recent Publications (PubMed)

Infant CD4 T-cell response to SARS-CoV-2 mRNA vaccination is restricted in cytokine production and modified by vaccine manufacturer.
(2025 Apr 4)
bioRxiv
Peters MQ, Young AL, Stolarczuk JE, Glad M, Layton E, Logue JK, Minkah NK, Chu HY, Englund JA, Sather DN, Seshadri C, Kachikis A, Harrington WE
Epidemiology of Symptomatic Human Metapneumovirus Infection in the CASCADIA Community-Based Cohort - Oregon and Washington, 2022-2024.
(2025 Apr 3)
MMWR Morb Mortal Wkly Rep 74(11): 188-193
Shakya M, Chu HY, Englund JA, Briggs-Hagen M, Carone M, Kuntz JL, Lockwood T, Midgley CM, Schmidt MA, Starita L, Weil AA, Wiegand RE, Naleway AL, Plumb ID
SARS-CoV-2 neutralizing antibody specificities differ dramatically between recently infected infants and immune-imprinted individuals.
(2025 Apr 15)
J Virol 99(4): e0010925
Dadonaite B, Burrell AR, Logue J, Chu HY, Payne DC, Haslam DB, Staat MA, Bloom JD
Household Transmission and Genomic Diversity of Respiratory Syncytial Virus (RSV) in the United States, 2022-2023.
(2025 Mar 14)
Clin Infect Dis
Cox SN, Roychoudhury P, Frivold C, Acker Z, Babu TM, Boisvert CL, Carone M, Ehmen B, Englund JA, Feldstein LR, Gamboa L, Grindstaff S, Grioni HM, Han PD, Hoffman KL, Kim HG, Kuntz JL, Lo NK, Lockwood CM, McCaffrey K, Mularski RA, Hatchie TL, Reich SL, Schmidt MA, Smith N, Starita LM, Varga A, Yetz N, Naleway AL, Weil AA, Chu HY
Corrigendum to "Reopening schools safely and educating youth (ROSSEY) study: Protocol for a community-based, cluster randomized controlled trial" [Contemporary Clinical Trials, 139 (2024) 107480].
(2025 May)
Contemp Clin Trials 152(): 107873
Ramirez M, Shah PD, Chu HY, Garza L, Linde S, Garrison MM, Zhou C, Bishop S, Ibarra G, Ko LK
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