Faculty

Helen Y Chu

Professor, Epidemiology
Professor, Medicine - Allergy and Infectious Dis.
Adjunct Professor, Global Health
Term Professorship, Medicine - Allergy and Infectious Dis.


Education

MPH Epidemiology, University of Washington, 2012
MD Medicine, Duke University Medical Center, Durham, NC, 2005
BA Cornell University, 2001

Research Areas

Research Interests

Dr. Chu's research is focused on maternal immunization, in particular vaccines against influenza and respiratory syncytial virus (RSV). She studies the virologic and immunologic correlates of protection from respiratory viral infections in pregnant women, infants, and older adults, and performs clinical trials of vaccine candidates in both domestic and international sites, including Nepal and Bangladesh. She has developed immunologic assays to study transplacental transfer and decay kinetics of RSV antibody, and nosocomial and household transmission of respiratory viruses by genotypic analysis and molecular sequencing.

Recent Publications (PubMed)

Health and Economic Impact of COVID-19 Surveillance Testing in Seattle Homeless Shelters: A Cost-Effectiveness Analysis.
(2025 Apr)
AJPM Focus 4(2): 100307
Cox SN, Chow EJ, Rolfes MA, Mosites E, Sharma M, Chu HY, Zimmermann M
T cell immune response to influenza vaccination when administered prior to and following autologous CAR-T cell therapy.
(2025 Mar 1)
Transplant Cell Ther
Kinoshita H, Walti CS, Webber K, Pezzella G, Jensen-Wachspress M, Lang H, Shuey K, Boonyaratanakornkit J, Pergam SA, Chu HY, Bollard CM, Keller MD, Hill JA
Generation of antigen-specific paired chain antibody sequences using large language models.
(2025 Feb 17)
bioRxiv
Wasdin PT, Johnson NV, Janke AK, Held S, Marinov TM, Jordaan G, Vandenabeele L, Pantouli F, Gillespie RA, Vukovich MJ, Holt CM, Kim J, Hansman G, Logue J, Chu HY, Andrews SF, Kanekiyo M, Sautto GA, Ross TM, Sheward DJ, McLellan JS, Abu-Shmais AA, Georgiev IS
Knowledge About Respiratory Syncytial Virus and Acceptance of Infant Monoclonal Antibody for RSV and RSV Vaccination During Pregnancy.
(2025 Feb 1)
Pediatr Infect Dis J 44(2S): S162-S166
Kuntz JL, Babu TM, Feldstein LR, Englund JA, Frivold CJ, Groom HC, Smith N, Varga AM, Cox SN, Fortmann SP, Mularski RA, Schmidt MA, Weil AA, Boisvert CL, Hollcroft M, Hatchie TL, Lo N, MacMillan MP, Reich S, Yetz N, Chu HY, Naleway AL
APMAT analysis reveals the association between CD8 T cell receptors, cognate antigen, and T cell phenotype and persistence.
(2025 Feb 6)
Nat Commun 16(1): 1402
Xie J, Chen DG, Chour W, Ng RH, Zhang R, Yuan D, Choi J, McKasson M, Troisch P, Smith B, Jones L, Webster A, Rasheed Y, Li S, Edmark R, Hong S, Murray KM, Logue JK, Franko NM, Lausted CG, Piening B, Algren H, Wallick J, Magis AT, Watanabe K, Mease P, Greenberg PD, Chu H, Goldman JD, Su Y, Heath JR
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