Trevor Bedford

Affiliate Professor, Epidemiology
Affiliate Professor, Genome Sciences


PhD Biology, Harvard University, 2008
BA Biological Sciences, University of Chicago, 2002


Fred Hutchinson Cancer Research Center
Box M2-C200
Arnold Building Room M1-B861
1100 Fairview Ave N
Seattle, WA 98109


Trevor Bedford is an Assistant Member at the Fred Hutchinson Cancer Research Center affiliated with the Vaccine and Infectious Disease Division and with the Computational Biology Program.

Research Interests

Dr. Bedford works at the interface of evolution, epidemiology and immunology. His research applies computational and statistical methods to understand viral dynamics. He is interested in using pathogen sequence data to make detailed inferences of pathogen transmission patterns. Previous research has focused on understanding antigenic drift in influenza virus, geographic spread of Ebola and within-host evolution of HIV.

Recent Publications (PubMed)

Positive selection underlies repeated knockout of ORF8 in SARS-CoV-2 evolution.
(2024 Apr 13)
Nat Commun 15(1): 3207
Wagner C, Kistler KE, Perchetti GA, Baker N, Frisbie LA, Torres LM, Aragona F, Yun C, Figgins M, Greninger AL, Cox A, Oltean HN, Roychoudhury P, Bedford T

Estimating the reproduction number and transmission heterogeneity from the size distribution of clusters of identical pathogen sequences.
(2024 Apr 9)
Proc Natl Acad Sci U S A 121(15): e2305299121
Tran-Kiem C, Bedford T

Integrating dynamical modeling and phylogeographic inference to characterize global influenza circulation.
(2024 Mar 15)
Parino F, Gustani-Buss E, Bedford T, Suchard MA, Trovão NS, Rambaut A, Colizza V, Poletto C, Lemey P

Comparative diagnostic utility of SARS-CoV-2 rapid antigen and molecular testing in a community setting.
(2024 Mar 26)
J Infect Dis
Kim AE, Bennett JC, Luiten K, O'Hanlon JA, Wolf CR, Magedson A, Han PD, Acker Z, Regelbrugge L, McCaffrey KM, Stone J, Reinhart D, Capodanno BJ, Morse SS, Bedford T, Englund JA, Boeckh M, Starita LM, Uyeki TM, Carone M, Weil A, Chu HY

Local-scale phylodynamics reveal differential community impact of SARS-CoV-2 in a metropolitan US county.
(2024 Mar)
PLoS Pathog 20(3): e1012117
Paredes MI, Perofsky AC, Frisbie L, Moncla LH, Roychoudhury P, Xie H, Bakhash SAM, Kong K, Arnould I, Nguyen TV, Wendm ST, Hajian P, Ellis S, Mathias PC, Greninger AL, Starita LM, Frazar CD, Ryke E, Zhong W, Gamboa L, Threlkeld M, Lee J, Stone J, McDermot E, Truong M, Shendure J, Oltean HN, Viboud C, Chu H, Müller NF, Bedford T

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