Trevor Bedford

Affiliate Associate Professor, Epidemiology
Affiliate Associate Professor, Genome Sciences


PhD Biology, Harvard University, 2008
BA Biological Sciences, University of Chicago, 2002


Trevor Bedford is an Assistant Member at the Fred Hutchinson Cancer Research Center affiliated with the Vaccine and Infectious Disease Division and with the Computational Biology Program.

Research Interests

Dr. Bedford works at the interface of evolution, epidemiology and immunology. His research applies computational and statistical methods to understand viral dynamics. He is interested in using pathogen sequence data to make detailed inferences of pathogen transmission patterns. Previous research has focused on understanding antigenic drift in influenza virus, geographic spread of Ebola and within-host evolution of HIV.

Recent Publications (PubMed)

Rapid and parallel adaptive mutations in spike S1 drive clade success in SARS-CoV-2.
(2021 Sep 14)
Kistler KE, Huddleston J, Bedford T

Emergence and expansion of SARS-CoV-2 B.1.526 after identification in New York.
(2021 Aug 24)
Annavajhala MK, Mohri H, Wang P, Nair M, Zucker JE, Sheng Z, Gomez-Simmonds A, Kelley AL, Tagliavia M, Huang Y, Bedford T, Ho DD, Uhlemann AC

Acute SARS-CoV-2 infections harbor limited within-host diversity and transmit via tight transmission bottlenecks.
(2021 Aug)
PLoS Pathog 17(8): e1009849
Braun KM, Moreno GK, Wagner C, Accola MA, Rehrauer WM, Baker DA, Koelle K, O'Connor DH, Bedford T, Friedrich TC, Moncla LH

SARS-CoV-2 Variants in Patients with Immunosuppression.
(2021 Aug 5)
N Engl J Med 385(6): 562-566
Corey L, Beyrer C, Cohen MS, Michael NL, Bedford T, Rolland M

SwabExpress: An end-to-end protocol for extraction-free covid-19 testing.
(2021 Jul 21)
Clin Chem
Srivatsan S, Heidl S, Pfau B, Martin BK, Han PD, Zhong W, van Raay K, McDermot E, Opsahl J, Gamboa L, Smith N, Truong M, Cho S, Barrow KA, Rich LM, Stone J, Wolf CR, McCulloch DJ, Kim AE, Brandstetter E, Sohlberg SL, Ilcisin M, Geyer RE, Chen W, Gehring J, Seattle Flu Study Investigators., Kosuri S, Bedford T, Rieder MJ, Nickerson DA, Chu HY, Konnick EQ, Debley JS, Shendure J, Lockwood CM, Starita LM

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