Ruanne Barnabas

Affiliate Professor, Epidemiology



DPhil Epidemiology, University of Oxford, 2005
MSc Epidemiology, University of Oxford, 2000
MBChB Medicine & Surgery, University of Cape Town (South Africa), 1997



55 Fruit St.
Boston, MA 02114
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Dr. Ruanne Barnabas is a South African physician-scientist and the Chief of the Division of Infectious Diseases at Massachusetts General Hospital (MGH).

Over the last 15 years, her research has focused on interventions for HIV and STD treatment and prevention and, more recently, on COVID-19 prevention. She is particularly interested in novel approaches that increase access to services. She has led clinical trials with companion health economic modeling to assess interventions' potential health and economic impact. For example, the Delivery Optimization for Antiretroviral therapy (DO ART) Study evaluated the efficacy and cost-effectiveness of decentralized, community-based ART initiation compared to standard clinic-based care. She also leads work assessing innovative strategies to increase access to care, including lottery incentives, home delivery, and ART monitoring. She is the Principal Investigator of the KEN SHE Study to assess the impact of single-dose human papillomavirus (HPV) vaccination in Kenya. Recently, her work has extended to COVID-19 prevention within households. Her work aims to identify effective and scalable HIV, HPV, and infectious disease treatment and prevention strategies to increase access across diverse communities and promote equity in health.

In addition to leading clinical trials and companion health economic modeling as an independently funded investigator, she also serves as an advisor to the World Health Organization and UNAIDS on cervical cancer elimination and treatment and prevention of HIV. She is on the planning committee for the AIDS 2022 conference. She was honored as a Fellow of the Infectious Diseases Society of America in 2020.

Dr. Barnabas graduated from the University of Cape Town, South Africa, where she received her medical degree. She received her research doctorate in medicine and clinical epidemiology from the University of Oxford, where she was a Rhodes Scholar. She completed her residency in South Africa and her fellowship in Infectious Diseases at the University of Washington, where she joined the faculty and was promoted to Professor of Global Health and Medicine before joining MGH in January 2022.  


Recent Publications (PubMed)

Results of a cluster randomized trial testing the Systems Analysis and Improvement Approach to increase cervical cancer screening in family planning clinics in Mombasa County, Kenya.
(2023 Nov 27)
Implement Sci 18(1): 66
Eastment MC, Wanje G, Richardson BA, Mwaringa E, Patta S, Sherr K, Barnabas RV, Mandaliya K, Jaoko W, Mcclelland RS

Adaptation of the sexual and reproductive empowerment scale for adolescents and young adults in Kenya.
PLOS Glob Public Health 3(10): e0001978
Harrington EK, Congo O, Kimanthi S, Dollah A, Onono M, Mugo N, Barnabas RV, Bukusi EA, Upadhyay UD

Simultaneous LC-MS/MS method for the quantitation of Azithromycin, Hydroxychloroquine and its metabolites in SARS-CoV-2(-/ +) populations using dried blood spots.
(2023 Sep 30)
Sci Rep 13(1): 16428
Chhonker YS, Aldhafiri WN, Soni D, Trivedi N, Steinbronn C, Johnson C, Karita HCS, Paasche-Orlow MK, Barnabas R, Arnold SL, Murry DJ

Prevalence and correlates of condom use at last sexual intercourse pre- and post-COVID-19 lockdown among adolescent girls and young women in central and western Kenya.
(2023 Jun)
Afr J Reprod Health 27(6): 70-76
Kimanthi S, Onono M, Otieno G, Barnabas RV, Njoroge B, Congo O, Biwott C, Mugo N, Harrington EK

State of the science and future directions for research on HIV and cancer: Summary of a joint workshop sponsored by IARC and NCI.
(2023 Sep 15)
Int J Cancer
Engels EA, Shiels MS, Barnabas RV, Bohlius J, Brennan P, Castilho J, Chanock SJ, Clarke MA, Coghill AE, Combes JD, Dryden-Peterson S, D'Souza G, Gopal S, Jaquet A, Lurain K, Makinson A, Martin J, Muchengeti M, Newton R, Okuku F, Orem J, Palefsky JM, Ramaswami R, Robbins HA, Sigel K, Silver S, Suneja G, Yarchoan R, Clifford GM

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