Ruanne Barnabas

Affiliate Professor, Epidemiology



DPhil Epidemiology, University of Oxford, 2005
MSc Epidemiology, University of Oxford, 2000
MBChB Medicine & Surgery, University of Cape Town (South Africa), 1997



55 Fruit St.
Boston, MA 02114
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Dr. Ruanne Barnabas is a South African physician-scientist and the Chief of the Division of Infectious Diseases at Massachusetts General Hospital (MGH).

Over the last 15 years, her research has focused on interventions for HIV and STD treatment and prevention and, more recently, on COVID-19 prevention. She is particularly interested in novel approaches that increase access to services. She has led clinical trials with companion health economic modeling to assess interventions' potential health and economic impact. For example, the Delivery Optimization for Antiretroviral therapy (DO ART) Study evaluated the efficacy and cost-effectiveness of decentralized, community-based ART initiation compared to standard clinic-based care. She also leads work assessing innovative strategies to increase access to care, including lottery incentives, home delivery, and ART monitoring. She is the Principal Investigator of the KEN SHE Study to assess the impact of single-dose human papillomavirus (HPV) vaccination in Kenya. Recently, her work has extended to COVID-19 prevention within households. Her work aims to identify effective and scalable HIV, HPV, and infectious disease treatment and prevention strategies to increase access across diverse communities and promote equity in health.

In addition to leading clinical trials and companion health economic modeling as an independently funded investigator, she also serves as an advisor to the World Health Organization and UNAIDS on cervical cancer elimination and treatment and prevention of HIV. She is on the planning committee for the AIDS 2022 conference. She was honored as a Fellow of the Infectious Diseases Society of America in 2020.

Dr. Barnabas graduated from the University of Cape Town, South Africa, where she received her medical degree. She received her research doctorate in medicine and clinical epidemiology from the University of Oxford, where she was a Rhodes Scholar. She completed her residency in South Africa and her fellowship in Infectious Diseases at the University of Washington, where she joined the faculty and was promoted to Professor of Global Health and Medicine before joining MGH in January 2022.  


Recent Publications (PubMed)

Efficacy and immunogenicity of a single dose of human papillomavirus vaccine compared to multidose vaccination regimens or no vaccination: An updated systematic review of evidence from clinical trials.
(2024 Aug)
Vaccine X 19(): 100486
Whitworth HS, Mounier-Jack S, Choi EM, Gallagher KE, Howard N, Kelly H, Mbwanji G, Kreimer AR, Basu P, Barnabas R, Drolet M, Brisson M, Watson-Jones D

Preventing tuberculosis with community-based care in an HIV-endemic setting: a modelling analysis.
(2024 Jun)
J Int AIDS Soc 27(6): e26272
Ross JM, Greene C, Broshkevitch CJ, Dowdy DW, van Heerden A, Heitner J, Rao DW, Roberts DA, Shapiro AE, Zabinsky ZB, Barnabas RV

Costs of home-delivered antiretroviral therapy refills for persons living with HIV: evidence from a pilot randomized controlled trial in KwaZulu-Natal, South Africa.
(2024 Jun 1)
Tseng AS, Barnabas RV, van Heerden A, Ntinga X, Sahu M

Cost-Effectiveness and Budget Impact Analysis of the Implementation of Differentiated Service Delivery Models for HIV Treatment in Mozambique: a Modelling Study.
(2024 May)
J Int AIDS Soc 27(5): e26275
Moiana Uetela DA, Zimmermann M, Chicumbe S, Gudo ES, Barnabas R, Uetela OA, Dinis A, Augusto O, Gaveta S, Couto A, Gaspar I, Macul H, Hughes JP, Gimbel S, Sherr K

Enhanced cervical cancer and HIV interventions reduce the disproportionate burden of cervical cancer cases among women living with HIV: A modeling analysis.
PLoS One 19(5): e0301997
Broshkevitch CJ, Barnabas RV, Liu G, Palanee-Phillips T, Rao DW

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