Faculty

Ruanne Barnabas

Affiliate Professor, Epidemiology

617-724-3467

Education

DPhil Epidemiology, University of Oxford, 2005
MSc Epidemiology, University of Oxford, 2000
MBChB Medicine & Surgery, University of Cape Town (South Africa), 1997

Contact

617-724-3467

55 Fruit St.
Boston, MA 02114
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Bio

Dr. Ruanne Barnabas is a South African physician-scientist and the Chief of the Division of Infectious Diseases at Massachusetts General Hospital (MGH).

Over the last 15 years, her research has focused on interventions for HIV and STD treatment and prevention and, more recently, on COVID-19 prevention. She is particularly interested in novel approaches that increase access to services. She has led clinical trials with companion health economic modeling to assess interventions' potential health and economic impact. For example, the Delivery Optimization for Antiretroviral therapy (DO ART) Study evaluated the efficacy and cost-effectiveness of decentralized, community-based ART initiation compared to standard clinic-based care. She also leads work assessing innovative strategies to increase access to care, including lottery incentives, home delivery, and ART monitoring. She is the Principal Investigator of the KEN SHE Study to assess the impact of single-dose human papillomavirus (HPV) vaccination in Kenya. Recently, her work has extended to COVID-19 prevention within households. Her work aims to identify effective and scalable HIV, HPV, and infectious disease treatment and prevention strategies to increase access across diverse communities and promote equity in health.

In addition to leading clinical trials and companion health economic modeling as an independently funded investigator, she also serves as an advisor to the World Health Organization and UNAIDS on cervical cancer elimination and treatment and prevention of HIV. She is on the planning committee for the AIDS 2022 conference. She was honored as a Fellow of the Infectious Diseases Society of America in 2020.

Dr. Barnabas graduated from the University of Cape Town, South Africa, where she received her medical degree. She received her research doctorate in medicine and clinical epidemiology from the University of Oxford, where she was a Rhodes Scholar. She completed her residency in South Africa and her fellowship in Infectious Diseases at the University of Washington, where she joined the faculty and was promoted to Professor of Global Health and Medicine before joining MGH in January 2022.  

 

Recent Publications (PubMed)

Meeting report: Considerations for trial design and endpoints in licensing therapeutic HPV16/18 vaccines to prevent cervical cancer.
(2024 Jul 13)
Vaccine
Dull PM, Achilles SL, Ahmed R, Barnabas RV, Campos NG, Chirgwin K, Cohen JA, de Sanjosé S, Doorbar J, Einstein MH, Emerson CI, Gottlieb SL, Hildesheim A, Qiao Y, Ruff P, Sampson JN, Sasieni P, Schiffman M, Shin H, Stanley MA, Trimble CL, Wentzensen N, Riemer AB, Schiller JT, Kreimer AR

Women's preferences for HIV prevention service delivery in pharmacies during pregnancy in Western Kenya: a discrete choice experiment.
(2024 Jul)
J Int AIDS Soc 27 Suppl 1(Suppl 1): e26301
Mugambi ML, Odhiambo BO, Dollah A, Marwa MM, Nyakina J, Kinuthia J, Baeten JM, Weiner BJ, John-Stewart G, Barnabas RV, Hauber B

State-level disparities in cervical cancer prevention and impact on outcomes in the U.S.: A modeling study.
(2024 Jun 12)
medRxiv
Alarid-Escudero F, Gracia V, Wolf M, Zhao R, Easterly CW, Kim JJ, Canfell K, de Kok IMCM, Barnabas RV, Kulasingam S

Estimating the Effect of COVID-19 Pandemic Restrictions on Self-reported Antiretroviral Therapy Use and Late Refill Visits Among People Living With HIV in Rural South Africa.
(2024 Aug 1)
J Acquir Immune Defic Syndr 96(4): 318-325
Tseng AS, Mugwanya KK, Szpiro AA, van Heerden A, Ntinga X, Schaafsma TT, Barnabas RV

Efficacy and immunogenicity of a single dose of human papillomavirus vaccine compared to multidose vaccination regimens or no vaccination: An updated systematic review of evidence from clinical trials.
(2024 Aug)
Vaccine X 19(): 100486
Whitworth HS, Mounier-Jack S, Choi EM, Gallagher KE, Howard N, Kelly H, Mbwanji G, Kreimer AR, Basu P, Barnabas R, Drolet M, Brisson M, Watson-Jones D

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