MS
May 16, 2022
Shifting Perspective – Can Behavioral Health Care Resources Reduce State Firearm Homicide Rates?
IntroductionFirearm homicide rates have risen steadily over the last decade. Two potential forms of intervention discussed by policy makers include firearm safety legislation and behavioral health resources. We sought to determine if a relationship exists between a state’s behavioral health resources and firearm related homicide rate.MethodsWe conducted a time-series cross-sectional analysis using the state and…
Life’s Simple 7 in relation to supraventricular and ventricular arrhythmias on extended ambulatory cardiac monitoring: The Multi-Ethnic Study of Atherosclerosis
Background: The Life’s Simple 7 (LS7) metric consists of seven health behaviors and measures that are known risk factors for cardiovascular disease. Relatively little is known about the association of LS7 score with cardiac arrhythmias.Methods: In the setting of the Multi-Ethnic Study of Atherosclerosis (MESA), we studied LS7 score, assessed at the 2010-2102 study visit,…
The Utilization and Safety of Per Oral Endoscopic Myotomy (POEM) for Achalasia in the US
Background: Clinical trials show that per oral endoscopic myotomy (POEM) has similar efficacy to pneumatic dilation (PD) and laparoscopic heller myotomy (LHM) for relief of achalasia symptoms. We describe the diffusion of POEM into clinical practice and evaluate unanswered questions regarding safety and the burden of healthcare utilization after POEM.Methods: Retrospective cohort study of achalasia…
Effect of Human Immunodeficiency Virus Infection on Human Papillomavirus Clearance among Women in Senegal, West Africa
Background. Persistent infection with human papillomavirus (HPV) is associated with development of cervical-related disease.Methods. A total of 174 Senegalese women completed health questionnaires and were tested for Human Immunodeficiency Virus (HIV) upon enrollment, as well as were tested HPV at baseline and during follow up. The 2-year cumulative incidence of clearance of type-specific HPV infection…
May 14, 2022
Socioeconomic Factors and Adherence to Healthcare Recommendations in Adolescent and Young Adult Cancer Survivors
Introduction: The majority of adolescent and young adult (AYA) cancer survivors do not receive recommended healthcare surveillance after completing cancer therapy. The impact of socioeconomic status and social support factors such as income, education, marital status, and insurance on healthcare adherence among AYA cancer survivors is unknown. Methods: Five cancer centers invited eligible survivors diagnosed…
May 12, 2022
Effect of Internal Standard Normalization of Microbiome Data on Outcomes of a Controlled Feeding Study and a Longitudinal Study in a Multiethnic Cohort
Standardization would benefit the interpretability of human microbiome data because unintended variability can be introduced at each level of data production and processing. One way to bring standardization to microbiome studies is with internal standards (IS). In three microbiome sequencing methods—16S rRNA gene sequencing, and metagenomic and metatranscriptomic sequencing—this standardization can involve the addition of…
Association of CPS Post-Response Daycare Services with Child Physical Abuse Recidivism
Introduction: Provision of services to families is a tool used by child welfare agencies after child maltreatment is reported, with an intention of preventing future child maltreatment reports. Little is known about the effectiveness of individual services in preventing child physical abuse recidivism.Methods: A retrospective cohort study was performed of data from 23 states contributing…
May 10, 2022
Hyperoxia After Pediatric Cardiac Arrest: Association with Survival and Neurological Outcomes
Objective: To evaluate the association between hyperoxia in the first 24 hours after in-hospital pediatriccardiac arrest and mortality and poor neurological outcome. Design: Retrospective cohort study. Setting: Tertiary care freestanding children’s hospital. Patients: Patients younger than 18 years of age with in-hospital cardiac arrest between December 2012 and December 2019, who achieved return of circulation…
August 5, 2021
Investigating Health Inequality in Primary Care Spatial Accessibility Among Races and Ethnicities in King County Using a Geospatial Approach
Distance to healthcare providers is a significant barrier to health care access in the U.S. Healthcare utilization and disease burden have been found to increase as the distance between patients and primary care physicians increase. Although spatial accessibility to primary care resources has been studied using different methods in recent decades, few studies have addressed…
An investigation of expression quantitative trait loci in interferon genes in childhood asthma using RNA-sequencing data
Background: Asthma is the most common chronic disease among children and yet, many of the underlying mechanisms of severe disease remain poorly understood. Expression quantitative trait loci (eQTL) can provide mechanistic insight into the consequences of asthma risk variants and help explain variation in asthma severity. We identified and evaluated eQTLs in interferon molecular networks…
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