MPH
September 18, 2024
Modification of Firearm Law-Firearm Injury Association by Economic Disadvantage
To assess whether the association between firearm law restrictiveness and firearm-related events in the US is modified by community distress and economic connectedness (EC).Methods: National cross-sectional study of firearm incidents (interpersonal and unintentional firearm events) occurring between 1/2015-12/2021 using the Gun Violence Archive (GVA). Exposures were community distress (Distressed Communities Index, DCI), EC, and year-state-level…
Association Between Time of Day of Combination Immune Checkpoint Inhibitor Administration and Overall Survival in Advanced Melanoma Patients
Immune checkpoint inhibitor (ICI) therapy has significantly improved the median overall survival of melanoma patients; however, many patients do not have clinical benefit from ICI therapy. The prognostic role of modifiable factors, such as the time of ICI administration, in immunotherapy treatment outcomes has not been well examined. Recent studies suggest that administration of ICIs…
Characterizing Sociodemographic, Behavioral Correlates, and Trends of Non-binary/genderqueer Patients at Public Health Seattle and King County Sexual Health Clinic
Non-binary/genderqueer (NB/GQ) individuals are a distinct but understudied population within the LGBTQ+ community. We sought to characterize sociodemographic behaviors and STI outcomes for NB/GQ patients attending the Sexual Health Clinic (SHC) and examine how gender identity among SHC patients has evolved over time. Methods: We used Public Health Seattle-King County (PHSKC) SHC data from 2016-2023…
Physical Inactivity and Obesity in Relation to Tumor Site and Age Onset for CRC on the Rising Incidence of Early-onset Colon Cancer and Early-onset Rectal Cancer
Overall incidence of colorectal cancer (CRC) has declined in recent decades; however, the incidence of early-onset CRC, particularly early-onset rectal cancer, has been increasing steadily since the mid-1990s among younger adults. The factors underlying observed increases in early-onset rectal cancer remain unclear. This study assessed the association of physical activity and obesity with early-onset rectal…
Building Demolitions and Police-reported Crime in Philadelphia, 2013-2023
Vacant properties in urban cities have been shown to be associated with increases in all police-reported crime and violent police-reported crime incidents. Building demolitions conducted in the name of blight removal are of increasing interest as non-carceral violence prevention methods. Objective: Our study aim was to examine if buildings demolished for safety reasons in Philadelphia…
Rectal Douching is not associated with Incident Rectal Gonorrhea or Chlamydia among Men Who Have Sex with Men (MSM)
Prior studies have identified an association between rectal douching and prevalent rectal Neisseria gonorrhoeae (GC) and Chlamydia trachomatis (CT), but few studies have examined associations with incident infections. We implemented a case-crossover study nested within the ExGen study, a 48-week cohort study conducted in Seattle, Washington, 2016-2018. Each week, ExGen participants completed a survey and…
Diagnostic Test Evaluation of Urine and Clinical Swab HPV Tests for Detection of HPV DNA and Pre-Invasive Cervical Lesions in Women in Senegal, 1998 – 2001
Cervical cancer remains a significant health challenge, particularly in Western Africa, where resources for screening are limited. This cross-sectional study evaluated the efficacy of urine HPV tests compared to swab HPV tests as diagnostic and screening tools for cervical cancer among 1,397 women aged 35 to 80 attending health centers in Dakar, Senegal, from 1998…
Examining the Association Between Perceived School Safety and Adolescent Electronic Cigarette Use in Washington State High School Students: 2023 Washington State Healthy Youth Survey
In the United States, adolescent substance use continues to be an important factor in negative health outcomes in adolescents. While previous research has established an association between school climate and adolescent use of alcohol, marijuana, and tobacco, minimal research has been conducted on the influences of school safety on adolescent electronic cigarette (e-cigarette) use in…
Associations of Pregnancy History and Complications with Incident Cardiovascular Disease Among American Indian Women: The Strong Heart Family Study
In the United States, cardiovascular disease is a leading cause of death among American Indian women. We examined the associations of parity (0/1, 2-4, >=5) and pregnancy complications (history of preeclampsia, protein in urine; eclampsia or seizures; gestational diabetes, hypertension) with incident cardiovascular disease (myocardial infarction, coronary heart disease, congestive heart failure, ischemic stroke) among…
Epidemiology of Human Metapneumovirus Infection in a Community-Based Setting, Seattle, WA, USA
To better quantify human metapneumovirus (hMPV) prevalence, associated risk factors, and genomic epidemiology in a community setting. Methods: This is a secondary analysis using data from the Seattle Flu Study (SFS). SFS was a community-based observational surveillance study for respiratory infections among clinical and community populations across the greater Seattle area from 2018-2022. SFS utilized…
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