MPH
November 24, 2020
Early Management of Community-Acquired Sepsis in a Regional Thai Referral Hospital: a Prospective Observational Study
PURPOSE The epidemiology and management of sepsis is poorly characterized in low- and middle-income countries. METHODS We performed a prospective observational cohort study of adults with community-acquired sepsis in a 1,420-bed regional referral hospital in northeast Thailand. Sepsis was defined as suspected infection plus organ dysfunction. RESULTS Between March 2013 and February 2014, 932 patients…
Evaluation of an mHealth SMS dialogue strategy to meet women’s and couples’ postpartum contraceptive needs in Kenya (Mobile WACh XY): A randomized controlled trial
OBJECTIVE To evaluate the effect of a two-way SMS intervention on postpartum contraceptive use among individual women and couple dyads. METHODS Mobile WACh XY was an unblinded randomized controlled trial conducted in two public county hospitals in western Kenya. Pregnant, HIV-negative women at least 14 years of age with estimated gestational age ≥28 weeks who…
Analysis of types of Tumor-Infiltrating Immune Cells in Oral Squamous Cell Carcinoma (OSCC) and their associations with survival of OSCC patients
BACKGROUND The 5-year survival associated with oral cancer (OSCC) is relatively low. Recent investigations have implicated the presence of tumor infiltrating lymphocytes (TILs) as independent prognostic markers in several malignancies, including oral cancer. However, the studies of oral cancer evaluated only a limited number of immune cell types as prognostic markers. CIBERSORT, a computational software…
Exploring Factors Associated with the Prioritization of South-to-South Partnerships by International Global Health Institutions in the Southern Hemisphere
INTRODUCTION Academic global health programs in North America have proliferated substantially since the turn of the century. Recent studies have sought to better understand the sustainability and impact of these programs and to evaluate the extent to which partnerships between global health academic institutions in North America and international institutions were mutually developed and are…
Evaluation of Zika Virus Testing Through the Washington State Department of Health
OBJECTIVES We used Washington State Department of Health (DOH) Zika surveillance data from January 1 to October 31, 2016 to (1) describe the population of individuals for whom Zika testing was requested, (2) determine whether health care provider (HCP) disciplines differ in appropriate referral practices for Zika testing, and (3) determine whether HCP disciplines differ…
The impact of HIV infection on cervical cancer presentation and survival in Uganda
OBJECTIVES To determine how HIV infection impacts cervical cancer stage and overall survival (OS) among Ugandan women. METHODS/MATERIALS Women diagnosed with cervical cancer were followed between 2013 and 2015 at the Uganda Cancer Institute (UCI). A Poisson regression model was fit to calculate prevalence ratios (PR) for the association between HIV infection and late stage…
Short and long-term patient outcomes following inhalation injury among burn patients
OBJECTIVE Our aim was to assess the effect of inhalation injury on in-hospital and post-discharge morbidity and mortality among burn patients. SUMMARY OF BACKGROUND DATA: There has been no systematic assessment of long-term outcomes following inhalation injury. Additionally, the literature remains sparse regarding many non-mortality in-hospital outcomes. Methods: This was a retrospective cohort study of…
Comprehensive characterization of humoral correlates of human immunodeficiency virus 1 superinfection acquisition in high-risk Kenyan women
HIV-1 superinfection, in which an infected individual acquires a second HIV-1 infection from a different partner, is one of the only settings in which HIV acquisition occurs in the context of a pre-existing immune response to natural HIV infection. There is evidence that initial infection provides some protection from superinfection, particularly after 6 months of…
November 23, 2020
Management of GNR bacteremia in HCT: shifting patterns for outpatient antibiotic therapy in the modern era
Gram-negative rod bacteremia (GNRB) is a leading cause of morbidity and mortality in recipients of an allogeneic hematopoietic cell transplant (HCT). Treatment for these patients has historically occurred in the inpatient setting; however, shifts have been made towards outpatient care as it is associated with lower rates of hospital acquired infections (HAIs) and better use…
The Association Between Maternal Work Precarity and Infant Low Birth Weight in a Nationally Representative Cohort of Women in the United States
As a larger proportion of women enter and remain in the workforce, consideration should be given to how work characteristics can affect pregnancy outcomes. We investigated the association between maternal work precarity and delivery of a low birth weight infant. Data on work characteristics and covariates were collected from 2,871 women enrolled in the National…
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