Department of Epidemiology

MPH


November 24, 2020

Short and long-term patient outcomes following inhalation injury among burn patients

OBJECTIVE Our aim was to assess the effect of inhalation injury on in-hospital and post-discharge morbidity and mortality among burn patients. SUMMARY OF BACKGROUND DATA: There has been no systematic assessment of long-term outcomes following inhalation injury. Additionally, the literature remains sparse regarding many non-mortality in-hospital outcomes. Methods: This was a retrospective cohort study of…


Comprehensive characterization of humoral correlates of human immunodeficiency virus 1 superinfection acquisition in high-risk Kenyan women

HIV-1 superinfection, in which an infected individual acquires a second HIV-1 infection from a different partner, is one of the only settings in which HIV acquisition occurs in the context of a pre-existing immune response to natural HIV infection. There is evidence that initial infection provides some protection from superinfection, particularly after 6 months of…


November 23, 2020

Management of GNR bacteremia in HCT: shifting patterns for outpatient antibiotic therapy in the modern era

Gram-negative rod bacteremia (GNRB) is a leading cause of morbidity and mortality in recipients of an allogeneic hematopoietic cell transplant (HCT). Treatment for these patients has historically occurred in the inpatient setting; however, shifts have been made towards outpatient care as it is associated with lower rates of hospital acquired infections (HAIs) and better use…


The Association Between Maternal Work Precarity and Infant Low Birth Weight in a Nationally Representative Cohort of Women in the United States

As a larger proportion of women enter and remain in the workforce, consideration should be given to how work characteristics can affect pregnancy outcomes. We investigated the association between maternal work precarity and delivery of a low birth weight infant. Data on work characteristics and covariates were collected from 2,871 women enrolled in the National…


Risk of Delirium and Use of Regional Analgesia in Geriatric Trauma Patients with Multiple Rib Fractures

OBJECTIVE To examine the risk of delirium in geriatric trauma patients with rib fractures treated with systemic opioids alone compared to those treated with regional analgesia (RA). METHODS Cohort study of patients ≥ 65 years with ≥ 3 rib fractures admitted to Harborview Medical Center from 2011-2016. The primary outcome was delirium positive ICU days….


Examining psychological distress across intersections of immigrant generational status, race, poverty, and gender

INTRODUCTION While many studies have documented the health outcomes of immigrants, little is known about the direct and intersectional influences of generational status on mental health. METHODS We conducted a population-based cross-sectional study using data from the California Health Interview Survey from 2015-2016 (N=41,754) to examine the prevalence of psychological distress (self-reported experience in the…


Feeding practices among vulnerable newborns in Vietnam: a pre- and post-evaluation of integrating a human milk bank into newborn care services

INTRODUCTION Infant feeding practices and lactation support when mother’s own milk is unavailable, especially among vulnerable infants in neonate intensive care unit situations (i.e. pre-term, low birthweight) are not well understood globally. Integration of human milk banking services and provision of donor human milk as early essential newborn care may offer the support and resources…


The Association of Sleep Apnea and Cancer in Veterans

OBJECTIVE To test the association between pre-existing obstructive sleep apnea (OSA) and subsequent cancer in a large, long-term cohort of veteran patients. METHODS This retrospective matched cohort study included all veteran patients diagnosed with OSA 1993-2013 by ICD-9 codes in any Veterans Affairs facility and probability matched veteran patients without OSA. Cancer diagnoses were identified…


The Effect of the Shikamana Peer-and-Provider Intervention on Depressive Symptoms, Alcohol Use, and Other Drug Use among Gay, Bisexual, and Other Men Who Have Sex with Men (GBMSM) in Kenya

Kenyan gay, bisexual, and other men who have sex with men (GBMSM) face unique stigma and discrimination, which may contribute to adverse mental health symptoms, and could limit antiretroviral therapy (ART) adherence among GBMSM living with HIV. This secondary analysis of data from a randomized pilot study evaluated whether the Shikamana peer-and-provider intervention was associated…


Alcohol, Tobacco, and Illicit Drug Use as Risk Factors for Onward HIV Transmission Among Men Who Have Sex with Men & Transgender Women in Lima, Peru

In 2016, there were about 70,000 (55,00–94,000) people living with HIV in Peru, with a prevalence of 16.4% among men who have sex with men (MSM) and 18.5% among transgender people.1 The aim of this study was to assess the association of heavy drinking, AUDIT score, tobacco use, and illicit drug use as independent risk…



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