MPH
May 14, 2022
Fusobacterium Nucleatum Enrichment in Colorectal Cancer and its Relationship with Tumor Attributes
Background: Aspects of the human gut microbiome have recently been linked to the etiology of colorectal cancer (CRC). Specifically, the commensal microbe Fusobacterium nucleatum (F. nucleatum) has been implicated in the development and progression of CRC, and has been found to be enriched in colorectal tumor tissue. Reflecting the fact that CRC is a heterogenous…
May 12, 2022
The association between smartphone-derived population-level mobility and COVID-19 in 2020: a census tract-level analysis of King County
Stay-at-home orders were an important tool in mitigating the COVID-19 pandemic. This ecological study used small area estimation models to estimate the associations between mobility and social vulnerability with COVID-19 case counts under different lockdown conditions for all 397 census tracts in King County, Washington in 2020. Data was used from Safegraph’s Social Distancing Metrics…
COVID-19 Vaccine Hesitancy in a US Public University Cohort
COVID-19 is a threat to university reopening. Universities are sites of dense human contact, congregate living, and heterogenous mixing patterns that may increase risk of viral transmission within and between social groups. Understanding attitudes toward vaccine uptake is critical to strategic reopening. At the University of Washington, we conducted a prospective observational study of SARS-CoV-2…
Characterization of patients seeking care at a Sexual Health Clinic who report engaging in exchange sex
Background: People who exchange sex (PWES) for money or drugs are at increased risk of HIV and other sexually transmitted infections (STIs) and may need tailored prevention and care services. Our objective was to characterize patients in the Public Health – Seattle & King County Sexual Health Clinic who reported engaging in exchange sex and…
May 10, 2022
Contraceptive Use Among Cisgender Women with Bacterial Sexually Transmitted Infections: A Cross-Sectional Study
Little is known about contraceptive use among women with bacterial sexually transmitted infections (STIs), despite their high risk for unplanned pregnancy. This analysis describes contraceptive use and interest in long-acting reversible contraception (LARC) among women with bacterial STIs. This cross-sectional study included 1,623 women ages 13 to 45 with bacterial STIs who completed a public…
Hepatitis C Prevalence, Correlates, and Social Networks among Cisgender Women who Participate in Sex Work in Seattle, WA
Background: Globally, injection drug use (IDU) is common among cisgender women who participate in sex work (CWSW), placing them at heightened risk of HCV acquisition and transmission. However, the epidemiology of HCV among CWSW in the United States is not well understood. In this study among CWSW in Seattle, we sought to estimate HCV prevalence,…
A prospective study of the association between living with an adult who misuses alcohol during childhood and major depressive disorder in adulthood: Evaluating the role of child maltreatment, sex, school bonding, and neighborhood bonding
Purpose: This prospective cohort study evaluated (1) the association between living with adult alcohol misuse during childhood and chronicity of major depressive disorder (MDD) during one’s thirties, (2) whether the association is explained by child maltreatment, and (3) whether the association is moderated by sex, school bonding, and neighborhood bonding during childhood. Methods: Longitudinal data…
January 14, 2021
Evaluating Measures of HIV Risk Perception with a Mixed Method Approach Among Adolescent Girls and Young Women Using PrEP in Kenya
Introduction: Pre-exposure prophylaxis (PrEP) for HIV prevention is a promising HIV prevention option for young African women. The evidence of effective PrEP use in this population group is mixed, and has been tied to poor adherence. Discordance between assessed HIV risk and the actual experience of risk may underlie the dissonance observed between epidemiologic risk,…
Prenatal Exposure to Ambient Air Pollution, Gestational Weight Gain, and Offspring Birth Weight
Background. Ankylosing spondylitis (AS) patients have elevated cardiovascular (CV) morbidity and mortality compared to general population comparators of the same age and sex. Although obesity is an important and modifiable CV risk factor, there are few prospective studies addressing the impact of higher body mass index (BMI) on clinical outcomes in AS. The aim of…
Adverse Childhood Experiences and Systemic Inflammation in Adults in the United States
Background and significance: Adverse childhood experiences (ACEs) are associated with poor behavioral and physical health outcomes in adulthood. Though not fully elucidated, systemic inflammation is one mechanism through which ACEs are thought to affect health outcomes in adulthood. The objective of this study was to assess the relationship between ACEs and systemic inflammation and if…
Previous page Next page