Department of Epidemiology

Graduate


November 18, 2020

Health care service utilization of individuals in permanent supportive housing in Seattle, WA accessing care through Public Health – Seattle and King County’s Health Care for the Homeless Network

Introduction: Permanent supportive housing (PSH) programs combine non-time limited housing with optional supportive services, including case management and health care, and are designed for those facing barriers to housing stability. Prior studies suggest that PSH can reduce emergency room visits and health care expenditures for an individual while improving their housing stability and well-being. However,…


Engaging Male Partners in Home-based Couple Education and Testing for Syphilis and HIV

For HIV and other sexually transmitted infections (STIs), men seek care at more advanced stages of disease and are less likely to initiate treatment.1-4 Male partner participation in antenatal care (ANC) has been shown to increase male and female HIV testing,5,6 identification of HIV-discordant couples,7,8 female participation in ANC and uptake of PMTCT services1,9 as…


Receptiveness and Responsiveness of Using Social Media for Safe Firearm Storage Outreach in Washington State: A Mixed-Methods Study

Background: Childhood and adolescent firearm injury and death have increased over the past decade and become a major public health concern in the United States. There is a growing disparity in the incidence of these events occurring in rural compared to urban areas. Safe firearm storage have shown to be an effective measure to prevent…


Investigation of Pertussis Resurgence in King County, Washington

Introduction: Pertussis or “whooping cough” is an infectious disease caused by bacterium Bordetella pertussis. Despite widespread vaccination since the 1950s, it continues to cause epidemics in several countries. In fact, in the last three decades, many countries with high vaccination coverage have reported a resurgence in pertussis activity. Understanding the factors that led to pertussis…


Diet, inflammation, and genetic predictors of tissue-specific gene expression: A functionally-informed gene-environment interaction analysis for risk of colorectal cancer.

Colorectal cancer (CRC) is the second most commonly diagnosed cancer in both sexes combined worldwide, as well as the second leading cause of cancer deaths. Pathogenesis of CRC can be attributed to both genetic (G) and environmental (E) factors. Among environmental risk factors, dietary factors contribute significantly to the etiology of CRC. Extensive research has…


Serum Concentrations of Novel Vitamin D Biomarkers and Detection of Prevalent High-Risk HPV Infection

Introduction: Vitamin D has potential immunomodulating benefits in infection. While one prior population-based cross-sectional study showed a protective association between serum concentrations of 25(OH)D and high-risk HPV (hrHPV) infection, additional biomarkers present at different stages along the vitamin D metabolic pathway may more completely characterize vitamin D status than 25(OH)D alone. We evaluated cross-sectional associations…


Racial/Ethnic Disparities in Risk of Breast Cancer Mortality by Molecular Subtype and Stage at Diagnosis

Previous research has found significant survival disparities between African-American and white women among select stages and subtypes of breast cancer, however other racial/ethnic groups have been less well-studied. This study expands on previous research, examining differences in breast cancer-specific mortality across multiple racial and ethnic groups. Women diagnosed with a first primary invasive breast cancer…


Longitudinal Association between Greenspace and Type 2 Diabetes: Evidence from MESA

This study aimed to evaluate the longitudinal association between the abundance of nearby greenspace in urban and suburban environments and incident type 2 diabetes mellitus (T2DM). Data was used from the Multi-Ethnic Study of Atherosclerosis (MESA). Normal Difference Vegetation Index (NDVI) was used as a proxy for greenspace. Exposure categories used NDVI median values from…


A Retrospective Cohort Study of Race and Ethnicity, Pre-pregnancy Weight, and Pregnancy Complications

Objective: To examine relationships between race/ethnicity, pre-pregnancy overweight/obesity status, and pregnancy complications: gestational diabetes (GDM), preeclampsia, and cesarean-delivery. Methods: We conducted a large retrospective population-based cohort study among mothers who delivered a singleton live birth in hospitals that participated in the Obstetrics Clinical Outcomes Assessment Program database (N=57,144). Race/ethnicity was categorized into mutually exclusive groups…


Assessing Optimal Intervention Targets for Respiratory Infections in Structured Populations

Background: Respiratory Viral Infections (RVI) are one of the most common health conditions globally, and are an enormous burden to health systems and society in terms of direct medical expenses and indirect productivity losses. Despite progress made in the 20th century with the introduction of antibiotics, vaccines, and antivirals there are no specific interventions for…



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