Graduate
November 18, 2020
Sex Misclassification in the BRFSS and its Implications for Assessing Transgender and Gender Nonconforming Reproductive Health: A Quantitative Bias Analysis
National surveys based on probability sampling methods, such as the Behavior Risk Factor and Surveillance Survey (BRFSS), are crucial tools for unbiased estimates of disparities in health and healthcare access among gender minorities. The BRFSS began offering an optional sexual orientation and gender identity module in 2014, capturing transgender and gender nonconforming (TGNC) identity among…
Hospital Resource Utilization and Presence of Advance Directives at the End of Life for Adults with Congenital Heart Disease
OBJECTIVE Overall healthcare resource utilization by adults with congenital heart disease has increased dramatically in the last two decades. No prior studies have examined utilization at the end of life. The objective of this study is to better understand the patterns and influences on the intensity of care at the end of life for adults…
Transplant-Associated Thrombotic Microangiopathy (TA-TMA) is a Multifactorial Disease Unresponsive to Immunosuppressant Withdrawal
Background: Transplant-associated thrombotic microangiopathy (TA-TMA) after allogeneic hematopoietic cell transplantation (HCT) has not been well-characterized in large population studies with clinically adjudicated cases. Methods: We performed a retrospective cohort study of adults who underwent allogeneic HCT between 2006 and 2015 to determine the incidence of and risk factors for TA-TMA, and to describe its natural…
Proton Pump Inhibitors (PPI), H2 Blocker Use, and Risk of Inflammatory Bowel Disease (IBD) in Children
BACKGROUND Previous longitudinal and cross-sectional studies have shown that changes in the composition of the gut microbiota are associated with IBD. Thus, it is plausible that drugs that alter the microbiome may increase the risk of future IBD. Previous studies have examined the association of Proton Pump Inhibitors (PPIs) and H2-receptor antagonists (H2 blockers) with…
Awareness of HIV Pre-Exposure Prophylaxis (PrEP) and Predictors of Interest in PrEP Among HIV-negative Persons Who Inject Drugs in Seattle, Washington
Background: HIV pre-exposure prophylaxis (PrEP) is safe and effective for use in people who inject drugs (PWID), but studies indicate that PrEP is underutilized in this population. We assessed awareness of PrEP and investigated predictors of interest in PrEP among PWID in Seattle, Washington. Methods: This study analyzed data from a 2019 survey of PWID…
Rotavirus vaccines in low-income settings
BACKGROUND An estimated 200,000 deaths due to rotavirus diarrhea occur annually in children with most of the burden in low-income settings. Rotavirus is a double stranded RNA virus transmitted via the fecal-oral route. Without a vaccine, nearly all children <5 years old become infected with rotavirus and recurrent infection is common. Rotavirus vaccines continue to…
Investigating the sexual partnerships of transgender women in Lima, Peru to improve targeted HIV interventions
Background: Transgender women (TW) have a high burden of HIV but remain understudied in HIV research. One poorly understood aspect of HIV risk among TW is the source of HIV infection in epidemics driven by sexual transmission. TW primarily report sexual partnerships with hetero- or bisexual cisgender men, populations that generally have a low HIV…
Integrating data systems to improve HIV care engagement in King County, WA
Continuous engagement in HIV care and treatment is crucial for the health of persons living with HIV (PLWH) and for preventing HIV transmission to others. However, in the United States (US), care engagement, or retention in care, represents the biggest drop off in the HIV care continuum, which maps out the care process from HIV…
POLST-Discordant Intensive Care Near the End of Life: A Retrospective Cohort Study
Importance: Patients with chronic life-limiting illness frequently use the Physician Orders for Life Sustaining Treatment (POLST) to document preferences for limiting intensive care. However, the incidence and predictors of POLST-discordant care near the end of life are not known. Objective: To describe the incidence, predictors, and intensity of POLST-discordant intensive care among patients hospitalized near…
The Vaginal Microbiome: The Influence of Intramuscular Depot-medroxyprogesterone Acetate Initiation on Vaginal Microbiota and A Comparison of PCR Approaches for Use in Predicting HIV Acquisition
The vaginal microbiome is a key factor in women’s reproductive health and hormones may play an important role in the composition of vaginal bacterial communities. The vaginal microbiome is commonly evaluated using broad-range polymerase chain reaction (PCR) with next generation sequencing (NGS) or taxon-specific quantitative PCR (qPCR); both approaches have advantages and disadvantages. We sought…
Previous page Next page