Graduate
September 11, 2025
Amruta Sardeshmukh
August 26, 2025
Outcomes of lung cancer screening in a nation-wide matched cohort of people with HIV compared to people without HIV
Background: People with HIV are at higher risk for lung cancer than the general population; however, it remains uncertain whether they have similar outcomes from lung cancer screening. Objective: To compare lung cancer screening findings and outcomes in a nationwide matched cohort of people with and without HIV. Methods: This was a retrospective analysis of…
The association of gender-affirming care with PrEP use among transgender women in Seattle
Transgender women are inequitably burdened with HIV worldwide. Pre-exposure prophylaxis (PrEP) issafe and effective at preventing HIV acquisition, but uptake is low. Integrating HIV care and gender- affirming care may increase PrEP uptake. We conducted a cross-sectional study using the Seattle 2023- 2024 National HIV Behavioral Surveillance (NHBS-Trans) survey (N = 149). A composite score…
The Paradox of Resilience: Lower Mortality Among Unhoused Trauma Patients in the Pacific Northwest
There is a gap in knowledge in the role chronic stress plays in response to subsequent acute stressors, with equipoise as to whether chronic stress may be protective. To study the possibility that individuals who experience chronic stress may be more resilient to an acute stressor, we aim to measure the time-to-event differences between housed…
Tumor Microbial Biodiversity and Microsatellite Instability in Colorectal Cancer
Background: There is growing interest in characterizing how the gut microbiome is related to colorectal cancer (CRC) progression and etiology after several species have been found to be strongly enriched in certain molecular subtypes of CRC tumors. DNA mismatch repair deficiency in CRC is associated with a favorable prognosis and positive response to immunotherapy, and…
Establishing Age-Specific Normative Data for the NIH Toolbox among Urban-Dwelling American Indian and Alaska Native Elders in the URBANE Study
This study presents group norms for fluid, crystallized, and total cognition scores on the NIH Toolbox among urban-dwelling American Indian and Alaska Native (AI/AN) Elders. From 2021 to 2024, the URBan Native Elders study recruited 1007 (n = 994) Elders to elucidate risk and protective factors for Alzheimer’s Disease and related dementias (ADRD). Volunteers self-identified…
Users of a Container-Based Sanitation Service Experience High Sanitation-Related Quality of Life: A Prospective Cohort Study in Cap Haitien, Haiti
Sanitation users often value improved sanitation interventions for social benefits, such as improved safety and dignity. Some sanitation providers have started using well-being measurements to evaluate service impacts beyond infectious disease outcomes. In particular, the Sanitation Quality of Life (SanQoL) Index explores five attributes associated with sanitation wellbeing: health, disgust, shame, safety, and privacy. In…
Clinical Sub-Phenotypes of Acute Lung Allograft Dysfunction Associated with Chronic Lung Allograft Dysfunction
Background:Chronic lung allograft dysfunction (CLAD) is the leading cause of mortality after the first year following lung transplantation (LTx). Acute lung allograft dysfunction (ALAD), defined by a ≥10% decline in FEV₁ from baseline best for at least 3 weeks, is a precursor to CLAD. However, only 40% of LTx recipients with ALAD progress to CLAD…
August 12, 2025
Comparison of Three Treatment Regimens for Latent Syphilis of Late or Unknown Duration Using Public Health Surveillance Data
Background: The CDC recommends treating latent syphilis of late/unknown duration (LSUD) with three doses of intramuscular benzathine penicillin G (BPG) or twenty-eight days of oral doxycycline. This recommendation lacks high-quality evidence. Methods: Using public health surveillance data from King County, Washington, we conducted a retrospective cohort study comparing rates of serological cure (>=2-titer RPR decline)…
A study on the association between educational attainment and substance use disorder from ages 33 to 47, and the moderating role of perceived neighborhood social cohesion
A study on the association between educational attainment and substance use disorder from ages 33 to 47, and the moderating role of perceived neighborhood social cohesion. Shawna Hui Chair of the Supervisory Committee:Isaac Rhew Department of Epidemiology & Department of Psychiatry and Behavioral Sciences Purpose: Examine the association between educational attainment at age 27 and…
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