Graduate
December 22, 2023
Characterizing modifiable risk factors of breast cancer recurrence and mortality in a cohort of women with luminal, triple-negative, and HER2-overexpressing breast cancer
Breast cancer is the most common cancer diagnosed among women in the United States; ten to 20% of survivors will experience a recurrence in the decade after diagnosis. To improve the understanding of the relationship between modifiable risk factors and breast cancer recurrence and mortality, overall and by subtype, we evaluated the relationship between smoking,…
Evaluating the Association between Smoking Behaviors and Anal or Vulvar High-Grade Squamous Intraepithelial Lesion (HSIL) Recurrence
HPV-induced high-grade squamous intraepithelial lesions (HSILs) of the anus and vulva have high rates of recurrence after treatment. While many studies have demonstrated the positive association between smoking and primary lesion development, research on its association with anal and vulvar HSIL recurrence is limited. Methods: We used data from a randomized controlled trial assessing the…
Patterns of acute kidney injury and functional outcome scores in pediatric patients hospitalized with acute respiratory failure
Acute kidney injury (AKI) is diagnosed in up to 30% of children admitted to pediatric intensive care units (PICU) and is strongly associated with morbidity and mortality. In recent years, there has been an increased focus on patient-centered outcomes and quality of life among survivors of AKI. One study of pediatric sepsis patients with AKI…
December 21, 2023
Multiple adverse childhood experiences and maternal mental health outcomes among Kenyan mothers with and without HIV
Adverse childhood experiences (ACEs) reflect childhood exposure to abuse, neglect, and family stressors, and there is consistent evidence that ACEs are associated with subsequent poor mental health outcomes. ACEs experienced by women who are mothers (referred to as maternal ACEs) can have lasting effects for mothers and may have impacts transmitted to their children. Few…
Historical redlining and survival among children, adolescents, and young adults with cancer diagnosed between 2007-2019 in Seattle/Tacoma
Historic redlining has been associated with inferior survival in adult-onset cancers, however whether there is an association in pediatric, adolescent, and young-adult-onset cancers is unknown. Methods: Cancer cases among individuals living in Seattle and Tacoma between 2007-2019 were identified via Cancer Surveillance System. Case redlining status was determined using Home Owner Loans Corporation (HOLC) data…
Outcomes of Kidney Transplantation Among Undocumented Immigrants in the United States
Kidney transplantation is the optimal treatment for end-stage kidney disease (ESKD), but undocumented immigrants in the United States are often excluded from health insurance coverage necessary to undergo kidney transplantation. Arguments in favor of such policies are based on concern that undocumented immigrants face increased risk for graft loss, but transplant outcomes in this population…
Association Between Isolation Source, Clonal Composition, and Antibiotic Resistance Genes in Escherichia coli Samples Collected in Washington State
The growing prevalence of antimicrobial resistance (AMR) represents a significant global health problem. AMR is caused by the overuse of antibiotics in humans, animals, and the environment, making it necessary to apply a One Health approach to address the problem. Methods: We used whole genome sequencing (WGS) data from 1,449 Escherichia coli (E. coli) isolates…
Tiny but Mighty: Association between fine particulate matter (PM2.5) and infant mortality in a North Carolina Birth Cohort (2003-2015)
Many studies have quantified the association between fine particulate matter (PM2.5) and adult mortality. Several studies have evaluated particulate matter (PM10) and postneonatal mortality, but there are relatively few studies about PM2.5 and infant mortality. We investigated the association between long-term PM2.5 exposure and all infant mortality, neonatal mortality and postneonatal mortality.Methods: We conducted an…
Long COVID in young adults on a university campus
To determine the prevalence of long COVID in young adults in a university setting and to describe risk factors for long COVID in this population Methods: This is a prospective cohort study conducted between December 2021 and February 2023 among research study participants in the Husky Coronavirus Testing (HCT) program at the University of Washington…
Workplace Suicides Before and During the COVID-19 Pandemic: Results from the National Violent Death Reporting System, 2013-2020
This study examines the occurrence of workplace suicides and their contextual factors before and during the COVID-19 pandemic using data from the Centers for Disease Control’s National Violent Death Reporting System (NVDRS). The study analyzes demographic, geographical, occupation, and circumstantial factors in workplace suicides and explores changes in these factors during the pandemic. The data…
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