Graduate
December 22, 2023
Trajectories, predictors, and impact on neurocognition of viral control among children living with HIV in Kenya
Children with HIV have poorer viral control than adults. Early initiation of effective antiretroviral therapy (ART) is essential for suppressing virus and recovering immunity; however, children are less likely to attain viral suppression than adults due to inadequate treatment dosing for weight, drug resistance, and barriers to adherence. Similar to adults, during viral suppression replication-competent…
Multilevel sociodemographic and socioeconomic disparities in COVID-19 outcomes in the Central Puget Sound region, 2020-2021
Presence of at least one underlying health condition (UHC) is positively associated with severe COVID-19. Although disparities in severe COVID-19 outcomes by race, ethnicity, and socioeconomic position (SEP) are extensively documented, there is little research examining these associations beyond the effect of UHCs. Studies also show regions of lower SEP and higher racial residential segregation…
Mental Health Care Utilization in Latinx Young Adults Who Grew Up in Rural or Small-Town U.S. Communities by Racial/Ethnic Immigrant Generational Status
To evaluate (1) differences in mental health care utilization across young adulthood by racial/ethnic immigrant generational status for young adults who grew up in a rural setting, (2) whether these differences are explained by language barriers and health insurance coverage, and (3) whether these differences vary longitudinally over the young adulthood period.Methods: Four years of…
Characterizing modifiable risk factors of breast cancer recurrence and mortality in a cohort of women with luminal, triple-negative, and HER2-overexpressing breast cancer
Breast cancer is the most common cancer diagnosed among women in the United States; ten to 20% of survivors will experience a recurrence in the decade after diagnosis. To improve the understanding of the relationship between modifiable risk factors and breast cancer recurrence and mortality, overall and by subtype, we evaluated the relationship between smoking,…
Evaluating the Association between Smoking Behaviors and Anal or Vulvar High-Grade Squamous Intraepithelial Lesion (HSIL) Recurrence
HPV-induced high-grade squamous intraepithelial lesions (HSILs) of the anus and vulva have high rates of recurrence after treatment. While many studies have demonstrated the positive association between smoking and primary lesion development, research on its association with anal and vulvar HSIL recurrence is limited. Methods: We used data from a randomized controlled trial assessing the…
Patterns of acute kidney injury and functional outcome scores in pediatric patients hospitalized with acute respiratory failure
Acute kidney injury (AKI) is diagnosed in up to 30% of children admitted to pediatric intensive care units (PICU) and is strongly associated with morbidity and mortality. In recent years, there has been an increased focus on patient-centered outcomes and quality of life among survivors of AKI. One study of pediatric sepsis patients with AKI…
December 21, 2023
Multiple adverse childhood experiences and maternal mental health outcomes among Kenyan mothers with and without HIV
Adverse childhood experiences (ACEs) reflect childhood exposure to abuse, neglect, and family stressors, and there is consistent evidence that ACEs are associated with subsequent poor mental health outcomes. ACEs experienced by women who are mothers (referred to as maternal ACEs) can have lasting effects for mothers and may have impacts transmitted to their children. Few…
Historical redlining and survival among children, adolescents, and young adults with cancer diagnosed between 2007-2019 in Seattle/Tacoma
Historic redlining has been associated with inferior survival in adult-onset cancers, however whether there is an association in pediatric, adolescent, and young-adult-onset cancers is unknown. Methods: Cancer cases among individuals living in Seattle and Tacoma between 2007-2019 were identified via Cancer Surveillance System. Case redlining status was determined using Home Owner Loans Corporation (HOLC) data…
Outcomes of Kidney Transplantation Among Undocumented Immigrants in the United States
Kidney transplantation is the optimal treatment for end-stage kidney disease (ESKD), but undocumented immigrants in the United States are often excluded from health insurance coverage necessary to undergo kidney transplantation. Arguments in favor of such policies are based on concern that undocumented immigrants face increased risk for graft loss, but transplant outcomes in this population…
Association Between Isolation Source, Clonal Composition, and Antibiotic Resistance Genes in Escherichia coli Samples Collected in Washington State
The growing prevalence of antimicrobial resistance (AMR) represents a significant global health problem. AMR is caused by the overuse of antibiotics in humans, animals, and the environment, making it necessary to apply a One Health approach to address the problem. Methods: We used whole genome sequencing (WGS) data from 1,449 Escherichia coli (E. coli) isolates…
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