Graduate
December 22, 2023
Factors associated with guideline-concordant biomarker testing in patients with stage IB-IIIA non-small cell lung cancer
Even with recent advances in identifying oncogenic genomic alterations and developing targeted therapies for non-small cell lung cancer (NSCLC), the uptake of molecular testing remains suboptimal among patients with advanced NSCLC, and comparable estimates for molecular testing in earlier stage NSCLC have not previously been published. This study describes and identifies factors associated with the…
Reliability of IgG serum antibodies, the electronic health record, and self-report in estimating urogenital and extragenital Chlamydia trachomatis infections in men who have sex with men
Few studies have examined the systemic antibody response in extragenital Chlamydia trachomatis (CT) infections. We estimate seroprevalence of IgG serum antibodies to CT among a cohort of men who have sex with men (MSM) with and without current infections stratified by anatomic site. We also examine the reliability of IgG serum antibodies, the electronic health…
Elevated body mass index, dementia risk, and post-mortem neuropathology
Over two-thirds of Americans aged 20 and over are considered overweight or obese. Compared to those who are within the healthy weight range as determined by body mass index (BMI), overweight and obese individuals are higher risk for poorer cognitive performance and structural brain pathology on neuroimaging studies. In addition, previous studies have shown a…
Associations of Mental Health Disorders, and Social Support with Retention in HIV Care Following Routine HIV Testing in a Refugee Settlement in Uganda
Uganda hosts a large refugee population, including individuals from neighboring countries with high HIV prevalence. Retention in HIV care for this population is crucial to improve health outcomes and reduce HIV transmission rates. Retention is essential to decreasing viral load and adverse health outcomes, all of which are difficult to manage with the complexities of…
Associations of Magnesium Intake with Acyclic Pelvic Pain and Dysmenorrhea
Pelvic pain (with or without endometriosis) is responsible for the deterioration of quality of life, chronic absenteeism and truancy, and loss of intimate relationships. Magnesium is a mineral that aids in muscular relaxation and can relieve cramps in a variety of muscles, including those in the pelvic floor. Little is known about the role of…
Cofactors of neonatal mortality and hospitalization in western Kenya
Although global neonatal mortality has been declining over the past several decades, it remains a major contributor to infant and childhood mortality rates. Determining the biological, psychosocial, and behavioral cofactors of neonatal mortality and hospitalization can help identify high-risk populations and behaviors associated with adverse neonatal health outcomes and will be relevant to research and…
Association of Neighborhood Disadvantage and COVID-19 and Influenza Vaccine Uptake and Positivity Among Kaiser Permanente Washington Flu Vaccine Effectiveness Subjects, 2018 – 2022
Neighborhoods with high Area Deprivation Index (ADI) scores have been linked to an increased risk of viral transmission and lower vaccine uptake. Subsequently, ADI has informed public health efforts and interventions at the neighborhood level, especially in the context of the COVID-19 pandemic. Understanding granular patterns and disparities in vaccine uptake and viral transmission is…
Factors associated with costly and potentially burdensome hospital care among patients with dementia and respiratory failure
Understanding contributors to costly and potentially burdensome hospital care for critically ill patients with dementia is of interest to healthcare systems and may facilitate efforts to ensure care is concordant with patients’ goals. We conducted an electronic health record (EHR)-based retrospective cohort study of 298 adults with dementia identified using International Classification of Diseases codes….
Comparison of Chlamydia trachomatis Seroprevalence and Risk Factors for Infection Among Women who have Sex with Women and Women who have Sex with Men in the 2013-2016 cycles of the National Health and Nutrition Examination Survey, United States
Little is known about the lifetime prevalence and risk factors for sexually transmitted infections (STIs) among cisgender women who have sex with women (WSW), despite this subpopulation being at risk for STIs. Using data from a large, nationally-representative survey, we estimated the seroprevalence of Chlamydia trachomatis (CT) among WSW and compared it to seroprevalence in…
Associations of Total Testosterone with Cardiometabolic Biomarkers among Women with Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) affects 6–12% of women of reproductive age in the United States. Women with PCOS are at a higher risk of experiencing cardiovascular and metabolic diseases such as diabetes; however, mechanisms linking PCOS to the development of diabetes remain unclear. This study aimed to investigate the association of total testosterone with cardiometabolic…
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