Department of Epidemiology

Graduate


December 26, 2023

Exploring the online and in-person epidemiology and etiology of white supremacy

Racism, a common facet of white supremacy, is increasingly understood to be a major threat to both the health of democracy in the United States and to the public’s health. However, our understanding of white supremacy and white supremacy culture is still limited. In this dissertation, we examine two violent examples of where and how…


Examining the Interplay of Social Support, Depression, and Blood Pressure: The Strong Heart Family Study

Compared to the general US population, American Indian (AI) adults have disproportionately higher rates of mental health symptoms, including depression. In 2019, over 18% (n=260,000) of surveyed American Indians/Alaska Natives (AI/AN) 18 years of age or older experienced mental illness during the past year. Several cross-sectional studies have also shown that depression is common in…


Improving the Efficiency and Effectiveness of Assisted Partner Services for HIV in Western Kenya

To control the HIV epidemic in Sub-Saharan Africa, it is crucial to increase the proportion of people who know their serostatus. In Kenya, approximately 1.6 million people are living with HIV (PLWH), of whom it is estimated that 21% are unaware of their status. Assisted partner services (APS) are programs that help to identify and…


Sexual Orientation and Influenza Vaccine Uptake in the Southern United States

Research at the national level suggests that gay or lesbian adults are significantly more likely to receive a flu vaccine compared to straight individuals, however, this relationship has not been explored at the regional level. The American South is known for its health disparities, high level of poverty, and social conservatism, which may impact the…


Associations Between Structural and Social Determinants of Health with Pediatric Surgical Site Infections

Determine if disparities exist in surgical site infections (SSI) for pediatric patients from minoritized language and racial and ethnic groups, and for those with a public insurance payor. Design, Setting, and Participants: This single-center cohort study retrospectively examined outcomes of patients undergoing eligible inpatient and outpatient surgical procedures from October 1, 2015 to September 30,…


Predictors of Mortality and Discharge Location for Patients Supported by Venoarterial Extracorporeal Membrane Oxygenation

Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a form of advanced life support that is increasingly used to treat cardiac or pulmonary failure, however morbidity and mortality for patients supported by VA-ECMO remains high. Elucidation of predictors of mortality and discharge location for survivors may aid clinicians, patients, and families in prognostication for patients supported by…


Adverse pregnancy outcomes, non-retention, eligibility of differentiated care and virologic failure among women living with HIV in prevention of vertical transmission programs

Provision of antiretroviral treatment (ART) to women living with HIV (WLWH) before and during pregnancy is key to prevention of vertical HIV transmission (or prevention of mother-to-child transmission [PMTCT]), including suppressed maternal HIV viral loads (VL) and improved maternal health. Studies have reported that ART use during pregnancy may affect the risks of adverse pregnancy…


Polygenic risk scores and current exogenous estrogen use on the risk of venous thromboembolism in the Heart and Vascular Health Study: a case-only approach

Venous thromboembolism (VTE) is a serious condition characterized by blood clot formation in veins. Exogenous hormone use is known to increase VTE risk, and understanding the interplay between genetic variants and hormone use can enhance our understanding of VTE development. Gene-environment interactions (GxE) can reveal how genetic factors modify the effect of environmental exposures, such…


KRAS Codon 12 and Codon 13 Mutations in Relation to Overall Survival among Colorectal Cancer Patients: A Systematic Review and Meta-Analysis

Oncogenic mutations in KRAS codon 12 and codon 13 within exon 2 are frequently occurring mutations in colorectal cancer (CRC). However, the existing published data on the association of KRAS codon 12 and codon 13 mutations on the survival of CRC patients remains inconclusive. To address this, we conducted a systematic PubMed search and meta-analysis….


Cofactors of Longitudinal Linear Growth Among Infants with and Without In-utero HIV/Antiretroviral Exposure in Kenya

Effective treatments have decreased vertical transmission of HIV and most infants born to women living with HIV (WLH) are HIV-exposed but uninfected (HEU). There is evidence that HEU infants have poorer growth than HIV-unexposed uninfected children (HUU). The biological and social mechanisms for growth deficits in HEU are unclear. There are few large studies comparing…



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