Faculty

Christopher Li

Research Professor, Epidemiology

206-667-7444

Education

MD Medicine, University of California (San Francisco), 2000
PhD Epidemiology, University of Washington, 2003
MPH Epidemiology, University of Washington, 2000

Contact

206-667-7444

Fred Hutch Cancer Center
Box 358080
1100 Fairview Ave N., M4-C308
P.O. 19024
Seattle, WA 98109
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Research Interests

Dr. Li is a cancer epidemiologist based at the Fred Hutchinson Cancer Research Center with research projects spanning cancer early detection/screening, etiology, and survivorship. He has significant expertise in cancer epidemiology and substantial experience in the design, leadership, and completion of multidisciplinary studies of cancer. Current research projects include: 1. A large population-based study of different molecular subtypes of breast cancer aimed at elucidating their risk factors and identifying novel subtype-specific tumor markers useful for predicting risk of disease recurrence (DOD Collaborative Innovator Award); 2. A nested case-control study of women with DCIS who did and did not go on to develop a second breast cancer aimed at developing novel epidemiologic, clinical, and molecular approaches for guiding clinical decision making for DCIS patients (R01); 3. Discovering and validating novel blood-based markers useful for the early detection of breast, colorectal, and ovarian cancers (U01); 4. Characterizing risk factors for second primary breast, lung, colorectal, and endometrial cancers among breast cancer survivors (R01); and 5. Discovering and validating novel biomarkers useful for assessing risk of recurrence among colorectal cancer survivors (R01 and U01). Selected leaderships activities include: 1. Serving as the co-PI of the Cancer Surveillance System (CSS), the Seattle-Puget Sound Surveillance, Epidemiology and End Results (SEER) cancer registry, 2. Chairing the DOD Breast Cancer Research Program’s Integration Panel (FY 2017), and 3. Co-chairing the 2017 AACR Conference on the Science of Cancer Health Disparities.

Recent Publications (PubMed)

Multi-ancestry transcriptome-wide association studies uncover insights into breast cancer genetics and biology.
(2026 May 30)
Nat Commun
Ping J, Jia G, Cai Q, Guo X, Wang J, Tao R, Li B, Bauer JA, Xie Y, Ambs S, Barnard ME, Chen Y, Choi JY, Gao YT, Garcia-Closas M, Gu J, Hu JJ, Iwasaki M, John EM, Kweon SS, Li CI, Matsuda K, Matsuo K, Nathanson KL, Nemesure B, Olopade OI, Pal T, Park SK, Park B, Press MF, Sanderson M, Sandler DP, Yao S, Zheng Y, Ahearn T, Brewster AM, Falusi A, Hennis AJM, Ito H, Kubo M, Lee ES, Makumbi T, Mapoko BSE, Noh DY, O'Brien KM, Ojengbede O, Olshan AF, Park MH, Reid S, Yamaji T, Zirpoli G, Butler EN, Huang M, Low SK, Obafunwa J, Weinberg CR, Zhang H, Zhao H, Ambrosone CB, Cote ML, Huo D, Haiman CA, Kang D, Palmer JR, Troester MA, Shu XO, Long J, Zheng W

Body Mass Index and Initiation of Cancer Screening: A Closer Look at Differences by Race, Ethnicity, and Sex in a Multi-Center Population.
(2026 May 25)
Am J Prev Med
Oshiro CE, Cushing-Haugen KL, Vecchio NJD, Alonge OD, Ghai NR, Green BB, Honda SA, Neslund-Dudas C, Ritzwoller DP, Skinner CS, Tao M, Vachani A, Chubak J, Corley DA, Haas JS, Li CI, Tiro JA, Rendle KA

Distinct Symptom Occurrence Subgroups Among Patients With Colorectal Cancer: Differences in Social Determinants of Health and Diet Quality.
(2026 May 26)
Res Nurs Health
Lee Y, Yang Q, Kay M, Bailey DE, Gigic B, Hardikar S, Toriola AT, Shibata D, Li CI, Byrd DA, Figueiredo JC, Strehli I, Mclaws M, Florou V, Ilozumba M, Erickson P, Medhe A, Ulrich CM, Gonzalez-Guarda RM

Isolation of a highly virulent colibactin-positive tumor-promoting strain of Escherichia coli from the gut microbiota of an adult.
(2026 May 26)
mSphere 11(5): e0021926
Weis AM, Matthews OJ, Bell R, Pershing NL, Dankwardt A, Fleming BA, Gigic B, Schneider M, Hardikar S, Toriola AT, Shibata D, Li CI, Byrd DA, Stephens WZ, Ulrich CM, Mulvey MA, Round JL

Racial and ethnic differences in gastric cancer by stage of diagnosis in the United States (2009-2019).
(2026 Apr 2)
Cancer Epidemiol Biomarkers Prev
Urujeni C, Epplein M, Li CI, Pete D

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