Faculty

Christopher I-Fu Li

Research Professor, Epidemiology

206-667-7444

Education

MD Medicine, University of California (San Francisco), 2000
PhD Epidemiology, University of Washington, 2003
MPH Epidemiology, University of Washington, 2000

Contact

206-667-7444

Fred Hutch Cancer Center
Box 358080
1100 Fairview Ave N., M4-C308
P.O. 19024
Seattle, WA 98109
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Research Interests

Dr. Li is a cancer epidemiologist based at the Fred Hutchinson Cancer Research Center with research projects spanning cancer early detection/screening, etiology, and survivorship. He has significant expertise in cancer epidemiology and substantial experience in the design, leadership, and completion of multidisciplinary studies of cancer. Current research projects include: 1. A large population-based study of different molecular subtypes of breast cancer aimed at elucidating their risk factors and identifying novel subtype-specific tumor markers useful for predicting risk of disease recurrence (DOD Collaborative Innovator Award); 2. A nested case-control study of women with DCIS who did and did not go on to develop a second breast cancer aimed at developing novel epidemiologic, clinical, and molecular approaches for guiding clinical decision making for DCIS patients (R01); 3. Discovering and validating novel blood-based markers useful for the early detection of breast, colorectal, and ovarian cancers (U01); 4. Characterizing risk factors for second primary breast, lung, colorectal, and endometrial cancers among breast cancer survivors (R01); and 5. Discovering and validating novel biomarkers useful for assessing risk of recurrence among colorectal cancer survivors (R01 and U01). Selected leaderships activities include: 1. Serving as the co-PI of the Cancer Surveillance System (CSS), the Seattle-Puget Sound Surveillance, Epidemiology and End Results (SEER) cancer registry, 2. Chairing the DOD Breast Cancer Research Program’s Integration Panel (FY 2017), and 3. Co-chairing the 2017 AACR Conference on the Science of Cancer Health Disparities.

Recent Publications (PubMed)

Racial and ethnic differences in gastric cancer by stage of diagnosis in the United States (2009-2019).
(2026 Apr 2)
Cancer Epidemiol Biomarkers Prev
Urujeni C, Epplein M, Li CI, Pete D

Dietary patterns associated with weight loss among patients with colorectal cancer during the first six months post-diagnosis: A cross-sectional analysis from the ColoCare Study.
(2026 Mar 30)
J Acad Nutr Diet
Hoobler R, Tabung FK, Lin T, Gigic B, Smith KS, Woodruff K, Crowder SL, Hardikar S, Byrd DA, Coletta AM, Sanchez A, Chaix A, Greathouse KL, Ilozumba MN, Ose J, Damerell V, Strehli I, McLaws M, Florou V, Huang LC, Shibata D, Figueiredo JC, Toriola AT, Li CI, Ulrich CM, Playdon MC

The phylum Fusobacteriota is associated with CRC-specific mortality: Results from the Translational Research Program in Cancer Differences across Populations.
(2026 Apr 1)
Cancer Epidemiol Biomarkers Prev
Thomas CE, LoroƱa NC, LaBrie SD, Curtis KR, Yin H, Ma N, Randolph TW, Qu C, Huyghe JR, Thomas S, Hsu L, Koehne AL, Nayemi S, Ammar H, Kahsai OJ, Redwood D, Li CI, Li L, Peters U, Figueiredo JC, Thomas TK, Phipps AI, Hullar MAJ

Up-to-date prevalence at recommended ages for discontinuing routine colorectal, cervical and lung cancer screening.
(2026 Feb 16)
J Natl Cancer Inst
Pocobelli G, Del Vecchio NJ, Cushing-Haugen K, Kamineni A, Corley DA, Rendle KA, Halm EA, Li CI, Oshiro CES, Carroll NM, Silver MI, Greenlee RT, Neslund-Dudas C, Breslau ES, Chubak J

Blood DNA methylation-predicted plasma protein levels and colorectal cancer survival.
(2026 Feb 1)
Clin Epigenetics 18(1): 24
Richards AR, Gomez MF, Dowling BI, Jean-Baptiste E, Gigic B, Figueiredo JC, Li CI, Shibata D, Toriola AT, Byrd DA, Ulrich CM, Stewart PA, Siegel EM, Kresovich JK

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