Faculty

Johanna W Lampe

Research Professor, Epidemiology
Adjunct Research Professor, Env. and Occ. Health Sciences

206-667-6580

Education

PhD Nutritional Science, University of Minnesota, 1990
MS Nutrition, University of Minnesota, 1986
BS Nutritional Science, University of Minnesota, 1982

Contact

206-667-6580

Fred Hutch Cancer Center
Box 358080
1100 Fairview Ave N., Arnold Building
PO Box 19024, Mailstop: M4-B402
Seattle, WA 98109

Research Interests

Dr. Lampe's research interests relate to the mechanisms by which components of diet, particularly constituents of plant food, alter susceptibility to and risk of cancer. Her primary research activities include using controlled dietary interventions in humans to determine how individual variation in biochemical response to high-plant food diets (e.g., biotransformation enzyme modulation, colonic environment changes) may explain differences in disease risk. The Lampe lab also studies the effect of diet on gut microbial community and the relationship of the gut microbiome to biomarkers of cancer risk and routinely measures isoflavones, lignans, and other biomarkers of plant-food intake for population-based studies.

Recent Publications (PubMed)

Stability and Variability of the Human Fecal Microbiome Over Two Years in the Multiethnic Cohort Study: A Metagenomic Analysis.
(2025 May 22)
Cancer Epidemiol Biomarkers Prev
Moosavi D, Curtis KR, Randolph TW, Kahsai OJ, Ammar H, Lim U, Cheng I, Wilkens LR, Le Marchand L, Lampe JW, Hullar MAJ

Highly sensitive DNA testing of Fusobacterium nucleatum (Fn) in colorectal tumors.
(2025 May 15)
Cancer Epidemiol Biomarkers Prev
Hullar MA, Kahsai OJ, Hill C, Levy L, Malen RC, Curtis KR, Ammar H, Sillah A, Reedy AM, Lampe JW, Ogino S, Potter JD, Newcomb PA, Phipps AI

Best Practices and Considerations for Conducting Research on Diet-Gut Microbiome Interactions and Their Impact on Health in Adult Populations: An Umbrella Review.
(2025 May)
Adv Nutr 16(5): 100419
Diacova T, Cifelli CJ, Davis CD, Holscher HD, Kable ME, Lampe JW, Latulippe ME, Swanson KS, Karl JP

Energy intake is associated with dietary macronutrient densities: inversely with protein and monounsaturated fat and positively with polyunsaturated fat and carbohydrate among postmenopausal females.
(2025 May)
Am J Clin Nutr 121(5): 1165-1175
Prentice RL, Aragaki AK, Zheng C, Manson JE, Tinker LF, Schoeller DA, Ravelli MN, Raftery D, Gowda GN, Navarro SL, Huang Y, Mossavar-Rahmani Y, Wallace RB, Johnson KC, Lampe JW, Neuhouser ML

Metagenomic estimation of absolute bacterial biomass in the mammalian gut through host-derived read normalization.
(2025 Jan 7)
bioRxiv
Tang G, Carr AV, Perez C, Sarmiento KR, Levy L, Lampe JW, Diener C, Gibbons SM

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In the News

Eating Fatty Fish Linked to Reduced Risk of Death
American Journal of Epidemiology, 02/03/2014
Joint Supplements May Prevent Colorectal Cancer
Cancer Causes & Control, 06/01/2013