Faculty

Walter A Kukull

Professor, Epidemiology

206-543-4560

Education

PhD Epidemiology, University of Washington, 1983
MS Psychology, Western Washington University, 1974

Contact

206-543-4560

Box 357236
Dept. of Epidemiology
1959 NE Pacific Street
Health Sciences, F-261G
Seattle, WA 98195
National Alzheimer's Coordinating Center
Box 354983
4311 11th Avenue NE #300
Seattle, WA 98105
View Website »

Research Interests

Dr Kukull's research is principally in the neurodegenerative, vascular and other conditions causing dementia and cognitive impairment. These conditions include Alzheimer's disease, Parkinson's/Lewy body disease, frontotemporal lobar degeneration, and cerebrovascular disease. Since 1999, as Director and PI of the National Alzheimer's Coordinating Center [U01AG016976], he is closely tied to the ~30 Alzheimer's Disease Centers nationwide, funded by National Institute on Aging. In addition to NACC work, he is an investigator with a number of other NIH grants.

Recent Publications (PubMed)

The effect of Alzheimer's disease genetic factors on limbic white matter microstructure.
(2025 Apr)
Alzheimers Dement 21(4): e70130
Lorenz A, Sathe A, Zaras D, Yang Y, Durant A, Kim ME, Gao C, Newlin NR, Ramadass K, Kanakaraj P, Khairi NM, Li Z, Yao T, Huo Y, Dumitrescu L, Shashikumar N, Pechman KR, Jackson TB, Workmeister AW, Risacher SL, Beason-Held LL, An Y, Arfanakis K, Erus G, Davatzikos C, Habes M, Wang D, Tosun D, Toga AW, Thompson PM, Mormino EC, Zhang P, Schilling K, Alzheimer's Disease Neuroimaging Initiative (ADNI)The BIOCARD Study TeamThe Alzheimer's Disease Sequencing Project (ADSP), Albert M, Kukull W, Biber SA, Landman BA, Johnson SC, Bendlin B, Schneider J, Barnes LL, Bennett DA, Jefferson AL, Resnick SM, Saykin AJ, Hohman TJ, Archer DB

Amyloid PET predicts longitudinal functional and cognitive trajectories in a heterogeneous cohort.
(2025 Mar)
Alzheimers Dement 21(3): e70075
Younes K, Johns E, Young CB, Kennedy G, Mukherjee S, Vossler HA, Winer J, Cody K, Henderson VW, Poston KL, Betthauser TJ, Bevis B, Brooks WM, Burns JM, Coombes SA, DeCarli C, DiFilippo FP, Duara R, Fan AP, Gibbons LE, Golde T, Johnson SC, Lepping RJ, Leverenz J, McDougall S, Rogalski E, Sanders E, Pasaye J, Sridhar J, Saykin AJ, Sridharan A, Swerdlow R, Trittschuh EH, Vaillancourt D, Vidoni E, Wang WE, Mez J, Hohman TJ, Tosun D, Biber S, Kukull WA, Crane PK, Mormino EC

Novel modelling approaches to elucidate the genetic architecture of resilience to Alzheimer's disease.
(2025 Mar 20)
Brain
Phillips JM, Dumitrescu LC, Archer DB, Regelson AN, Mukherjee S, Lee ML, Choi SE, Scollard P, Trittschuh EH, Kukull WA, Biber S, Mez J, Mahoney ER, Clifton M, Libby JB, Walters S, Bush WS, Engelman CD, Lu Q, Fardo DW, Widaman KF, Buckley RF, Mormino EC, Sanders RE, Clark LR, Gifford KA, Vardarajan B, Cuccaro ML, Pericak-Vance MA, Farrer LA, Wang LS, Schellenberg GD, Haines JL, Jefferson AL, Johnson SC, Albert MS, Keene CD, Saykin AJ, Risacher SL, Larson EB, Sperling RA, Mayeux R, Goate AM, Renton AE, Marcora E, Fulton-Howard B, Patel T, Bennett DA, Schneider JA, Barnes LL, Cruchaga C, Hassenstab J, Belloy ME, Andrews SJ, Resnick SM, Bilgel M, An Y, Beason-Held LL, Walker KA, Duggan MR, Klinedinst BS, Crane PK, Hohman TJ

Genome-wide pleiotropy analysis of longitudinal blood pressure and harmonized cognitive performance measures.
(2025 Feb 13)
medRxiv
Kang M, Ang TFA, Devine SA, Sherva R, Mukherjee S, Trittschuh EH, Gibbons LE, Scollard P, Lee M, Choi SE, Klinedinst B, Nakano C, Dumitrescu LC, Hohman TJ, Cuccaro ML, Saykin AJ, Kukull WA, Bennett DA, Wang LS, Mayeux RP, Haines JL, Pericak-Vance MA, Schellenberg GD, Crane PK, Au R, Lunetta KL, Mez J, Farrer LA

Evaluating the association of APOE genotype and cognitive resilience in SuperAgers.
(2025 Jan 7)
medRxiv
Durant A, Mukherjee S, Lee ML, Choi SE, Scollard P, Klinedinst BS, Trittschuh EH, Mez J, Farrer LA, Gifford KA, Cruchaga C, Hassenstab J, Naj AC, Wang LS, Johnson SC, Engelman CD, Kukull WA, Keene CD, Saykin AJ, Cuccaro ML, Kunkle BW, Pericak-Vance MA, Martin ER, Bennett DA, Barnes LL, Schneider JA, Bush WS, Haines JL, Mayeux R, Vardarajan BN, Albert MS, Thompson PM, Jefferson AL, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Alzheimer’s Disease Genetics Consortium (ADGC), The Alzheimer’s Disease Sequencing Project (ADSP), Crane PK, Dumitrescu L, Archer DB, Hohman TJ, Gaynor LS

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