Faculty

Holly R Harris

Affiliate Associate Professor, Epidemiology

206-667-2712

Education

ScD Harvard T.H. Chan,
MPH University of Southern California, 2005
BA Macalester College, 2000

Contact

206-667-2712

Fred Hutchinson Cancer Research Center
Box M4-B859
Program in Epidemiology, Division of Public Health Sciences
1100 Fairview Avenue North
Seattle, WA 98109

Research Interests

I am broadly interested in the impact of lifestyle, nutrition, and genetic factors on women’s health. Specifically, I have focused on ovarian and breast cancer, as well as on hormonally related conditions that have shared reproductive risk factors with these diseases, including endometriosis and uterine fibroids. Much of my research to date has focused on understanding the role of the potentially modifiable risk factors of diet and lifestyle on the risk of these conditions. A more recent facet of my research is to explore the interrelatedness of these conditions and their shared risk factors. As ovarian cancer is rare, I am particularly interested in identifying women, such as those with endometriosis, who may be at higher risk because these women may benefit from screening modalities for ovarian cancer which are currently not appropriate for population-based use. Identification of women at high risk for ovarian cancer and breast cancer is also important as it allows for targeted prevention strategies and can guide clinical decisions regarding frequency of screening and chemoprevention strategies for both of these cancers. Finally, understanding the influence of genetic factors, both alone or as a part of gene-environment interactions may facilitate prevention and help identify women most at risk for ovarian and breast cancer.

Recent Publications (PubMed)

Menopausal Hormone Therapy and Ovarian and Endometrial Cancers: Long-Term Follow-Up of the Women's Health Initiative Randomized Trials.
(2024 Aug 22)
J Clin Oncol
Chlebowski RT, Aragaki AK, Pan K, Haque R, Rohan TE, Song M, Wactawski-Wende J, Lane DS, Harris HR, Strickler H, Kauntiz AM, Runowicz CD

Risk factors for long COVID syndrome in postmenopausal women with previously reported diagnosis of COVID-19.
(2024 Aug 12)
Ann Epidemiol 98(): 36-43
Neuhouser ML, Butt HI, Hu C, Shadyab AH, Garcia L, Follis S, Mouton C, Harris HR, Wactawski-Wende J, Gower EW, Vitolins M, Von Ah D, Nassir R, Karanth S, Ng T, Paskett E, Manson JE, Chen Z

Pre-diagnosis tea and coffee consumption and survival after a diagnosis of ovarian cancer: results from the Ovarian Cancer Association Consortium.
(2024 Jul 18)
Br J Cancer
Nagle CM, Ibiebele TI, Bandera EV, Cramer D, Doherty JA, Giles GG, Goodman MT, Hanley GE, Harris HR, Jensen A, Kjaer SK, Lee AW, Milne RL, Qin B, Richardson J, Sasamoto N, Sieh W, Terry KL, Titus L, Trabert B, Wentzensen N, Wu AH, Berchuck A, Pike M, Pearce CL, Webb PM

Concurrent RB1 Loss and BRCA Deficiency Predicts Enhanced Immunologic Response and Long-term Survival in Tubo-ovarian High-grade Serous Carcinoma.
(2024 Aug 15)
Clin Cancer Res 30(16): 3481-3498
Saner FAM, Takahashi K, Budden T, Pandey A, Ariyaratne D, Zwimpfer TA, Meagher NS, Fereday S, Twomey L, Pishas KI, Hoang T, Bolithon A, Traficante N, Australian Ovarian Cancer Study Group, Alsop K, Christie EL, Kang EY, Nelson GS, Ghatage P, Lee CH, Riggan MJ, Alsop J, Beckmann MW, Boros J, Brand AH, Brooks-Wilson A, Carney ME, Coulson P, Courtney-Brooks M, Cushing-Haugen KL, Cybulski C, El-Bahrawy MA, Elishaev E, Erber R, Gayther SA, Gentry-Maharaj A, Gilks CB, Harnett PR, Harris HR, Hartmann A, Hein A, Hendley J, Hernandez BY, Jakubowska A, Jimenez-Linan M, Jones ME, Kaufmann SH, Kennedy CJ, Kluz T, Koziak JM, Kristjansdottir B, Le ND, Lener M, Lester J, Lubiński J, Mateoiu C, Orsulic S, Ruebner M, Schoemaker MJ, Shah M, Sharma R, Sherman ME, Shvetsov YB, Soong TR, Steed H, Sukumvanich P, Talhouk A, Taylor SE, Vierkant RA, Wang C, Widschwendter M, Wilkens LR, Winham SJ, Anglesio MS, Berchuck A, Brenton JD, Campbell I, Cook LS, Doherty JA, Fasching PA, Fortner RT, Goodman MT, Gronwald J, Huntsman DG, Karlan BY, Kelemen LE, Menon U, Modugno F, Pharoah PDP, Schildkraut JM, Sundfeldt K, Swerdlow AJ, Goode EL, DeFazio A, Köbel M, Ramus SJ, Bowtell DDL, Garsed DW

History of Infertility and Risk of Colorectal Cancer.
(2024 Aug 1)
Cancer Epidemiol Biomarkers Prev 33(8): 1129-1131
Farland LV, Lind KE, Roe DJ, Saquib N, Strickler HD, Qi L, Thomson CA, Harris HR

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