School of Public Health

EPI 524 CANCER: EPIDEMIOLOGY AND BIOLOGY

EPI 524 Cancer: Epidemiology And Biology (3)

Explores the epidemiology of major cancers (infection-related, breast, prostate, lung, colon, melanoma), with an emphasis on milestones in cancer mechanisms (such as tumor viruses, cell cycle, DNA repair, and metastasis). Integrates knowledge from different fields of cancer research, with guest lectures from experts in epidemiology and cancer biology. Prerequisite: either EPI 511 or EPI 512; either undergraduate biology coursework or instructor permission.

Winter 2018

Line Number Section ID Credits Days/Times Room/Bldg Instructor
14600A3.0Monday, Wednesday @ 10:30am - 11:50amT473 (HST)MARGARET M. MADELEINE
For a complete listing of Epidemiology courses, their elective categories, and when they are typically offered, please see the Epidemiology Course Planning Sheet

Additional Course Details

Combines an evaluation of the descriptive epidemiology of disparate cancers with an introduction to the biology of cancer. We build on concepts central to cancer biology to develop a comprehensive understanding of factors associated with cancer etiology and prevention.    

Topics Covered

  • Epidemiology of cancers of the breast, colon, lung, and pathogen-related cancers
  • Cancer biology topics include apoptosis, inflammation, invasion and metastasis and other cancer hallmarks.
  • Analyzing publicly available cancer registry data.

Learning Objectives

  • Describe and compare the epidemiology of several cancer types.
  • Explain the differences between normal and cancerous cells, and the progression from a normal cell to a cancerous cell.
  • Use publicly available cancer registry data and be able to plan studies using these data.
  • Describe several key mechanisms that underlie carcinogenesis of different cancers (e.g., DNA repair defects, activation of proto-oncogenes, inherited mutations, growth factors and their receptors)
  • Advance abilities to critically evaluate and interpret findings reported in the scientific literature on cancer research topics  
  • Demonstrate detailed knowledge regarding a particular cancer type and cancer risk factors.

Course Format

Lecture and discussion  

How You Will Be Evaluated

  • Participation in discussion of readings
  • 3 short essay assignments
  • Final project presentation/paper

Contact the Instructor

Margaret M. Madeleine (mmadelei@fredhutch.org)