Faculty

Nona Sotoodehnia

Adjunct Professor, Epidemiology
Professor, Medicine - Cardiology
John Laughlin Endowed Professorship in Cardiovascular Research, Medicine - Cardiology

206-287-2777

Education

MPH Harvard School of Public Health, 1996
MD Harvard Medical School, 1996
BS Massachusetts Institute of Technology, 1991

Contact

206-287-2777

Box 359748
WA

Bio

Dr. Sotoodehnia, the John and Cookie Laughlin Endowed Professor in Cardiology, is co-director of the Cardiovascular Health Research Unit. She is a general cardiologist at Harborview Medical Center.

She conducts research on the genomics and epidemiology of cardiovascular diseases and risk factors. Her research focus includes cardiac arrhythmias and sudden cardiac arrest, diabetes and coronary heart disease. She and her group are leading efforts in precision medicine, examining drug-gene interactions, risk prediction and drug safety. Her work investigates gender and ethnic differences in cardiovascular risk and outcomes. In addition, she has a long interest in international health and is helping lead efforts in cardiovascular treatments in Nepal.

Research Interests

  • Preventive cardiology
  • Arrhythmias including sudden cardiac death and atrial fibrillation
  • Coronary heart disease
  • Precision medicine
  • International health
  • Diabetes and gender 
  • Ethnic differences in cardiovascular risk and outcomes

Recent Publications (PubMed)

Long COVID and recovery from Long COVID: quality of life impairments and subjective cognitive decline at a median of 2 years after initial infection.
(2024 Nov 5)
BMC Infect Dis 24(1): 1241
Szewczyk W, Fitzpatrick AL, Fossou H, Gentile NL, Sotoodehnia N, Vora SB, West TE, Bertolli J, Cope JR, Lin JS, Unger ER, Vu QM

Circulating Blood Plasma Profiling Reveals Proteomic Signature and a Causal Role for SVEP1 in Sudden Cardiac Death.
(2024 Oct)
Circ Genom Precis Med 17(5): e004494
Duong T, Austin TR, Brody JA, Shojaie A, Battle A, Bader JS, Hong YS, Ballantyne CM, Coresh J, Gerszten RE, Tracy RP, Psaty BM, Sotoodehnia N, Arking DE

Genome-Wide Interaction Analyses of Serum Calcium on Ventricular Repolarization Time in 125 393 Participants.
(2024 Sep 3)
J Am Heart Assoc 13(17): e034760
Young WJ, van der Most PJ, Bartz TM, Bos MM, Biino G, Duong T, Foco L, Lominchar JT, Müller-Nurasyid M, Nardone GG, Pecori A, Ramirez J, Repetto L, Schramm K, Shen X, van Duijvenboden S, van Heemst D, Weiss S, Yao J, Benjamins JW, Alonso A, Spedicati B, Biggs ML, Brody JA, Dörr M, Fuchsberger C, Gögele M, Guo X, Ikram MA, Jukema JW, Kääb S, Kanters JK, Lifelines Cohort Study, Lin HJ, Linneberg A, Nauck M, Nolte IM, Pianigiani G, Santin A, Soliman EZ, Tesolin P, Vaccargiu S, Waldenberger M, van der Harst P, Verweij N, Arking DE, Concas MP, De Grandi A, Girotto G, Grarup N, Kavousi M, Mook-Kanamori DO, Navarro P, Orini M, Padmanabhan S, Pattaro C, Peters A, Pirastu M, Pramstaller PP, Heckbert SR, Sinner M, Snieder H, Völker U, Wilson JF, Gauderman WJ, Lambiase PD, Sotoodehnia N, Tinker A, Warren HR, Noordam R, Munroe PB

Trimethylamine N-Oxide and Related Gut Microbe-Derived Metabolites and Incident Heart Failure Development in Community-Based Populations.
(2024 Aug)
Circ Heart Fail 17(8): e011569
Tang WHW, Lemaitre RN, Jensen PN, Wang M, Wang Z, Li XS, Nemet I, Lee Y, Lai HTM, de Oliveira Otto MC, Fretts AM, Sotoodehnia N, DiDonato JA, Bäckhed F, Psaty BM, Siscovick DS, Budoff MJ, Mozaffarian D, Hazen SL

Epigenome-wide DNA Methylation Association Study of CHIP Provides Insight into Perturbed Gene Regulation.
(2024 Jul 16)
Res Sq
Levy D, Kirmani S, Huan T, Van Amburg J, Joehanes R, Uddin MM, Nguyen NQ, Yu B, Brody J, Fornage M, Bressler J, Sotoodehnia N, Ong D, Puddu F, Floyd J, Ballantyne C, Psaty B, Raffield L, Natarajan P, Conneely K, Carson A, Lange L, Ferrier K, Heard-Costa N, Murabito J, Bick A

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