MPH
November 18, 2020
Awareness of HIV Pre-Exposure Prophylaxis (PrEP) and Predictors of Interest in PrEP Among HIV-negative Persons Who Inject Drugs in Seattle, Washington
Background: HIV pre-exposure prophylaxis (PrEP) is safe and effective for use in people who inject drugs (PWID), but studies indicate that PrEP is underutilized in this population. We assessed awareness of PrEP and investigated predictors of interest in PrEP among PWID in Seattle, Washington. Methods: This study analyzed data from a 2019 survey of PWID…
Receptiveness and Responsiveness of Using Social Media for Safe Firearm Storage Outreach in Washington State: A Mixed-Methods Study
Background: Childhood and adolescent firearm injury and death have increased over the past decade and become a major public health concern in the United States. There is a growing disparity in the incidence of these events occurring in rural compared to urban areas. Safe firearm storage have shown to be an effective measure to prevent…
Serum Concentrations of Novel Vitamin D Biomarkers and Detection of Prevalent High-Risk HPV Infection
Introduction: Vitamin D has potential immunomodulating benefits in infection. While one prior population-based cross-sectional study showed a protective association between serum concentrations of 25(OH)D and high-risk HPV (hrHPV) infection, additional biomarkers present at different stages along the vitamin D metabolic pathway may more completely characterize vitamin D status than 25(OH)D alone. We evaluated cross-sectional associations…
Longitudinal Association between Greenspace and Type 2 Diabetes: Evidence from MESA
This study aimed to evaluate the longitudinal association between the abundance of nearby greenspace in urban and suburban environments and incident type 2 diabetes mellitus (T2DM). Data was used from the Multi-Ethnic Study of Atherosclerosis (MESA). Normal Difference Vegetation Index (NDVI) was used as a proxy for greenspace. Exposure categories used NDVI median values from…
A Retrospective Cohort Study of Race and Ethnicity, Pre-pregnancy Weight, and Pregnancy Complications
Objective: To examine relationships between race/ethnicity, pre-pregnancy overweight/obesity status, and pregnancy complications: gestational diabetes (GDM), preeclampsia, and cesarean-delivery. Methods: We conducted a large retrospective population-based cohort study among mothers who delivered a singleton live birth in hospitals that participated in the Obstetrics Clinical Outcomes Assessment Program database (N=57,144). Race/ethnicity was categorized into mutually exclusive groups…
November 17, 2020
Risk factors for health-related quality of life deterioration following pediatric critical illness
Background: Many children experience declines in health-related quality of life (HRQL) after critical illness, but it is unknown what components of HRQL are most affected. We aimed to evaluate risk factors for deterioration between baseline and post-discharge HRQL status in the individual components of common HRQL measures among pediatric survivors of critical illness. Methods: We…
Early diagnosis in infants born to HIV-positive adolescent compared to adult mothers in Kisumu, Kenya
Although many countries have made great efforts to establish prevention of mother to child HIV transmission (PMTCT) services, globally 160,000 children are newly infected with HIV each year. Early infant diagnosis (EID) of HIV is critical to the survival of HIV-positive infants. While adolescent girls, defined by WHO as 10-19 years olds, represent a growing…
Use of Bevacizumab for Newly Diagnosed Ovarian Cancer: A National Analysis
Objective: To describe the use patterns and costs of bevacizumab (BEV) for the upfront treatment of ovarian cancer (OC) in the US. Methods: We identified women ages 18 – 65 with newly diagnosed OC from 2008 to 2016 through the Truven Health MarketScan® database. Of these, women who underwent cancer-directed surgery and platinum-based chemotherapy within…
Evaluation of text message reminders to encourage re-testing for chlamydia and gonorrhea among female patients at the municipal STD Clinic in Seattle, WA
Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC) are bacterial sexually transmitted infections and are the most commonly reported infections in the United States. Infections with CT or GC can lead to adverse health effects for women, including pelvic inflammatory disease (PID), tubal factor infertility, ectopic pregnancy, and chronic pelvic pain. Women are at high risk…
Lethal Means Assessment in Psychiatric Emergency Services: Frequency and Characteristics of Assessment
Lethal means safety is an effective suicide prevention strategy with demonstrated results at the population and policy level, yet uptake at the individual-level is less well understood. Using automated data extraction methods, we conducted an investigation of psychiatric emergency service (PES) patients from 1/1/12 through 12/31/17 at one of the busiest emergency departments in the…
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