MPH
January 14, 2021
Correlates of HIV status non-disclosure by pregnant women living with HIV to their male partners in Uganda: a cross-sectional study
Background: HIV status disclosure by pregnant women living with HIV (PWLHIV) to their male partners is associated with improved maternal and infant outcomes. Understanding relationship factors associated with non-disclosure of HIV status by PWLHIV to their partners can inform the design of interventions to facilitate status disclosure. Methods: We conducted a cross-sectional study using enrollment…
Local-level Association of Social Deprivation and Serious Injuries in Washington State: An Ecological Cross-sectional Study
Background Injuries, a major source of morbidity and mortality, are associated with social determinants of health. To inform strategic prioritization and targeting of injury prevention resources, there is a need to better understand the relationship between specific community-level factors and serious injuries. Methods We conducted an ecological cross-sectional study in ZIP Code Tabulation Areas (ZCTAs)…
January 12, 2021
Non-gonococcal urethritis and its relationship to three novel bacterial vaginosis (BV) associated bacteria
Objective: Non-gonococcal urethritis (NGU) is the most common urethral syndrome in the United States, yet up to 50% of cases are of unknown etiology. Bacterial-vaginosis associated bacteria (BVAB), highly predictive of BV in cisgender women, have been detected in cisgender men and may explain some cases of NGU. We sought to determine the frequency and…
An evaluation of the performance characteristics of World Health Organization syndromic management for C. trachomatis and N. gonorrhoeae infections among female sex workers in Mombasa, Kenya
Abstract An evaluation of the performance characteristics of World Health Organization syndromic management for C. trachomatis and N. gonorrhoeae infections among female sex workers in Mombasa, Kenya Gregory Zane Chair of the Supervisory Committee: Dr. Jennifer Balkus Department of Epidemiology Objectives: To assess the performance characteristics of the World Health Organization’s (WHO) syndromic surveillance algorithms…
Weight gain following antiretroviral therapy (ART) initiation in ART-naive people living with HIV in the current treatment era
Objectives We evaluated weight change among people living with HIV (PLWH) initiating antiretroviral therapy (ART) in the current treatment era. Methods Between 2012-2019, in 8 Centers for AIDS Research Network of Integrated Clinical Systems (CNICS) sites, we identified 3232 ART-naïve PLWH starting 3-drug ART, including efavirenz (EFV), rilpivirine (RPV), atazanavir (ATV), darunavir (DRV), raltegravir (RAL),…
Diet quality and depressive symptoms in a cohort of American Indians: The Strong Heart Family Study
Background: Higher diet quality has been shown to be associated with a lower risk of depression compared to lower diet quality, though this relationship has not been studied in American Indians (AIs). We examined the relationship of diet quality with incidence of depressive symptoms in a prospective, family-based cohort of 1,100 AIs ≥14 years of…
November 25, 2020
Effect modification of the alcohol – colorectal cancer association
INTRODUCTION Alcohol consumption is an established risk factor for colorectal cancer (CRC). However, while studies have consistently reported elevated risk of CRC among heavy drinkers, associations at moderate levels of alcohol consumption are less clear. We conducted a meta-analysis of 16 studies of CRC to examine the shape of the alcohol-CRC association, investigate potential effect…
Trends in incidence of vancomycin-resistant enterococcus colonization and bacteremia among hematopoietic cell transplant recipients at a large comprehensive cancer care center
BACKGROUND Vancomycin-resistant Enterococcus (VRE) are important hospital-acquired pathogens among hematopoietic cell transplant (HCT) recipients. We examined the incidence and outcomes of patients with VRE colonization and bacteremia (VREB) over a ten-year period at a center that routinely screens and uses barrier precautions for VRE. METHODS Adults receiving their first allogeneic HCT at our center between…
Effects of Intubation Location on Risk of Ventilator Associated Events
BACKGROUND Ventilation is a crucial tool in modern medicine that allows for advanced respiratory support in critically ill patients. However, prolonged ventilation has been found to be linked with ventilator-associated conditions (VACs), which in turn are associated with multiple adverse hospital outcomes. OBJECTIVES To evaluate the association between intubation practices (using intubation locations as a…
Stressful Life Events in Pregnancy and Postpartum Depressive Symptoms among Women in Washington State
BACKGROUND Stressful life events (SLEs) such as job loss or death of a loved one are common in pregnancy. Studies have shown that women with SLEs during pregnancy are more likely to develop postpartum depressive symptoms (PDS). This study examined the association between stressful life events (SLEs) experienced one year before delivery and postpartum depressive…
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