MPH
December 21, 2023
Evaluating the association of prenatal PrEP exposure with perinatal and growth outcomes from infancy through early childhood
As pre-exposure prophlaxis (PrEP) implementation continues to scale-up among pregnant populations, accruing safety data following prenatal PrEP exposure remains important. Methods Data from the PrEP Implementation for Mothers in Antenatal Care study (NCT03070600) was analyzed to evaluate the relationship between prenatal PrEP exposure and birth and infant/child outcomes. Women enrolled during pregnancy at 20 maternal…
Relationship between bacterial diversity, specific urethral bacteria and incident NGU in men who have sex with women
Nongonococcal urethritis (NGU) is a common syndrome in men that is not well understood. Prior studies have investigated factors associated with prevalent NGU, but factors associated with incident NGU have rarely been examined. We evaluated potential precursors of incident NGU in a group of men who have sex with women (MSW) attending a sexual health…
Association of Patient Characteristics with Risk of Rheumatic Heart Disease in First-Degree Relatives of Index Cases in Nepal
Rheumatic heart disease (RHD) is associated with significant morbidity and mortality, particularly in low- and middle-income countries. First-degree relatives (FDR) of RHD patients share known risk factors for RHD: poverty, poor living conditions, crowding, poor hygiene, and potential shared genetic characteristics that lead to higher RHD risk. We sought to determine whether FDR screening would…
Association between environmental modifiable risk score and molecular subtypes in colorectal cancer patients
Colorectal cancer (CRC) is associated with several modifiable environmental risks, including dietary and non-dietary factors like calcium intake and smoking habits. It is unknown if the association between overall environmental risk and CRC is differentially associated with certain molecular subtypes.Methods: A total of 6389 cases and 6835 controls of European ancestry from 11 observational studies…
Does Racial Residential Segregation Influence Smoking Behaviors? The Multi-Ethnic Study of Atherosclerosis
Tobacco cigarette smoking remains the leading cause of preventable morbidity and mortality in the United States. Racial residential segregation (RRS) in American cities may be contributing to high rates of smoking in some communities. Yet, limited research exists investigating the association between segregation and smoking behaviors. The aim of this study was to examine the…
The role of multivitamins: an investigation into the association with colorectal cancer survival
Nutritional supplements are used by over half of United States adults, and many patients use supplements for their perceived anti-cancer benefit. Current evidence for the relationship between multivitamin use and colorectal cancer (CRC) survival is sparse. Some studies suggest that multivitamins may divert attention from healthful food-based diets or multivitamin use may be reflected in…
Associations of COVID-19 Status with Risk for Death and Hospitalization Among Prevalent and Incident Cardiovascular Medication Users
The relationship between cardiovascular disease/injury and COVID-19 has been well described, but the use of cardiovascular medication as a proxy for cardiovascular disease and injury has not been explored. Our study used electronic health record (EHR) data in a large prospective cohort of 17,003 patients from University of Washington, Seattle, WA, to assess the risk…
Trends in Chlamydia trachomatis Treatment Prescribing Practices in King County, Washington, 2010 – 2018
Chlamydia trachomatis (CT) is the most commonly reported bacterial sexually transmitted infection in the United States. In 2021, the CDC updated its CT treatment guidelines from equally recommending either azithromycin (1 gram as a single dose) or doxycycline (100mg twice daily for 7 days) to only recommending doxycycline as first line treatment after 2021. We…
Associations between Vaginal Microbiota and Cervicitis
Cervicitis is defined as the inflammation of the cervix. Many cases of cervicitis are caused by sexually transmitted infections (STIs); however, a substantial portion of cervicitis cases have no known etiology. Cervicitis is also known to be associated with bacterial vaginosis (BV), a clinical condition characterized by the transition of the vaginal microbiota from being…
December 20, 2023
Association of Bacterial Vaginosis With Chlamydia trachomatis Infection Among Women in Mombasa, Kenya: A Nested Case-Control Study
Objective: Evidence is mixed regarding the relationship between bacterial vaginosis (BV) and Chlamydia trachomatis (CT) acquisition; therefore, we assessed the relationship between recent BV and subsequent CT infection. Study Design: A nested case-control study was conducted using data and samples from cisgender women who reported engaging in transactional sex and who were participating in the…
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