Graduate
December 21, 2023
Associations of COVID-19 Status with Risk for Death and Hospitalization Among Prevalent and Incident Cardiovascular Medication Users
The relationship between cardiovascular disease/injury and COVID-19 has been well described, but the use of cardiovascular medication as a proxy for cardiovascular disease and injury has not been explored. Our study used electronic health record (EHR) data in a large prospective cohort of 17,003 patients from University of Washington, Seattle, WA, to assess the risk…
Trends in Chlamydia trachomatis Treatment Prescribing Practices in King County, Washington, 2010 – 2018
Chlamydia trachomatis (CT) is the most commonly reported bacterial sexually transmitted infection in the United States. In 2021, the CDC updated its CT treatment guidelines from equally recommending either azithromycin (1 gram as a single dose) or doxycycline (100mg twice daily for 7 days) to only recommending doxycycline as first line treatment after 2021. We…
Hemoptysis and serious outcomes in cystic fibrosis
Hemoptysis is a common and important complication in persons with cystic fibrosis (PwCF). Despite this, there is limited literature on the impact of hemoptysis on contemporary cystic fibrosis (CF) outcomes. We sought to evaluate whether hemoptysis increases risk of lung transplant or death without transplant in PwCF. We reviewed a dataset of PwCF ages 12…
Predictors of Disease Activity in Juvenile Idiopathic Arthritis at 12 and 24 Months After Diagnosis
Identification of characteristics associated with risk of active disease in Juvenile Idiopathic Arthritis (JIA) could inform treatment strategies early in the disease state. This study evaluates JIA disease activity outcomes and patient characteristics associated with active disease at 12- and 24-months post diagnosis from a single large US center. Methods: Disease activity status at 12-…
Association Between Prediagnostic Cigarette Smoking and Colorectal Cancer Survival by Molecular Subtypes and Age-onset Status.
In the United States, colorectal cancer (CRC) remains the third most commonly diagnosed malignancy in both men and women, and approximately 36% of CRC patients die within the first five years after diagnosis. Several factors are known to affect the survival of CRC patients, including smoking history; however, it is unclear whether previously-observed associations between…
Associations between Vaginal Microbiota and Cervicitis
Cervicitis is defined as the inflammation of the cervix. Many cases of cervicitis are caused by sexually transmitted infections (STIs); however, a substantial portion of cervicitis cases have no known etiology. Cervicitis is also known to be associated with bacterial vaginosis (BV), a clinical condition characterized by the transition of the vaginal microbiota from being…
December 20, 2023
Association of Bacterial Vaginosis With Chlamydia trachomatis Infection Among Women in Mombasa, Kenya: A Nested Case-Control Study
Objective: Evidence is mixed regarding the relationship between bacterial vaginosis (BV) and Chlamydia trachomatis (CT) acquisition; therefore, we assessed the relationship between recent BV and subsequent CT infection. Study Design: A nested case-control study was conducted using data and samples from cisgender women who reported engaging in transactional sex and who were participating in the…
December 21, 2022
Heterogeneity in HIV/STI Prevalence, Testing, and PrEP Use among Transgender and Non-binary People and their Partners in the US
Transgender and non-binary (TNB) people in the U.S. are disproportionately impact by HIV and sexually transmitted infections (STIs). As a result of socio-structural stigma, institutional barriers, and fear of mistreatment, and discrimination, TNB people experience significant barriers to engaging in health care, including HIV/STI prevention. In addition, the HIV/STI prevalence and behaviors of their sex…
Heart Rate Variability and Autonomic Function: A Study of Adolescents with Chronic Abdominal Pain and Healthy Adolescents
Background: Chronic abdominal pain is often accompanied by autonomic dysfunction. It is hypothesized that dysregulation of the autonomic nervous system (ANS) results in poorer physiological modulation to physical and psychological stress in the context of persistent pain. Research in adults with chronic pain conditions identified decreased parasympathetic activation using heart rate variability (HRV), as a…
New Insights into Neisseria gonorrhoeae (NG): Geographic heterogeneity in Black-White disparities and spatiotemporal trends among US females and the role of azithromycin use for STI treatment in antibiotic resistance
Gonorrhea (caused by the Neisseria gonorrhoeae (NG) bacterium) is the second most-commonly reported sexually transmitted infection (STI) in the United States (US) and can cause serious, permanent reproductive sequalae in females. Gonorrhea rates have increased rapidly in the US throughout the last 3 decades, while profound racial disparities have stubbornly persisted with non-Hispanic Black (NHB)…
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